| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.152087 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.128278 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.124469 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.113694 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.108296 |
| COG5 | component of oligomeric golgi complex 5 | 0.0973067 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0841537 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0814595 |
| ATP13A3 | ATPase type 13A3 | 0.0810929 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0734072 |
| GOLGA4 | golgin A4 | 0.0731278 |
| GDF15 | growth differentiation factor 15 | 0.0682926 |
| CALU | calumenin | 0.0660009 |
| SPAG9 | sperm associated antigen 9 | 0.0621096 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0619668 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.061695 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0612483 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0606102 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0586202 |
| MSN | moesin | 0.0579934 |
| WDR43 | WD repeat domain 43 | 0.0566761 |
| GPC6 | glypican 6 | 0.0560831 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0557781 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0531404 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0529961 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0529597 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0525706 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0504392 |
| ITGAV | integrin, alpha V | 0.0497409 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0496754 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0495846 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0480508 |
| CDK13 | cyclin-dependent kinase 13 | 0.0475407 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0472857 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0458299 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0451394 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0448167 |
| VMP1 | vacuole membrane protein 1 | 0.044073 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0438456 |
| ARRDC3 | arrestin domain containing 3 | 0.043641 |
| CADM1 | cell adhesion molecule 1 | 0.0432175 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0422277 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0416494 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0405561 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0403846 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0403336 |
| HELZ | helicase with zinc finger | 0.0402277 |
| SRPK2 | SRSF protein kinase 2 | 0.0398772 |
| VIM | vimentin | 0.0396056 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0395957 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0389684 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0389306 |
| FOXO3 | forkhead box O3 | 0.0388784 |
| PTK2 | protein tyrosine kinase 2 | 0.0388095 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0386154 |
| PLK2 | polo-like kinase 2 | 0.0384116 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0383669 |
| RNF220 | ring finger protein 220 | 0.0381511 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0381197 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0379988 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0378723 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0376973 |
| SBF2 | SET binding factor 2 | 0.0376474 |
| LRRC59 | leucine rich repeat containing 59 | 0.0375836 |
| DENND4C | DENN/MADD domain containing 4C | 0.0373197 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.037215 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0370488 |
| YME1L1 | YME1-like 1 ATPase | 0.036725 |
| SEPTIN9 | septin 9 | 0.0366438 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0364043 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.036128 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0361129 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0360829 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0359257 |
| FMNL2 | formin-like 2 | 0.0357808 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0356891 |
| IRS2 | insulin receptor substrate 2 | 0.035514 |
| RHEB | Ras homolog enriched in brain | 0.0354683 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0353397 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0351804 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0351143 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0350287 |
| NOP58 | NOP58 ribonucleoprotein | 0.0349544 |
| CTBP2 | C-terminal binding protein 2 | 0.0346603 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0343869 |
| GOLGA2 | golgin A2 | 0.0343343 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0341334 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0340641 |
| FNBP4 | formin binding protein 4 | 0.0340324 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0339568 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0338294 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0336767 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0336517 |
| COPA | coatomer protein complex, subunit alpha | 0.0335403 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0333169 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0331175 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.0329944 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0328611 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0328451 |
| ATXN2 | ataxin 2 | 0.0327845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.149294 |
| TXNRD1 | thioredoxin reductase 1 | -0.127564 |
| CD44 | CD44 molecule (Indian blood group) | -0.0834359 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.078999 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.078487 |
| TMSB10 | thymosin beta 10 | -0.0721096 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.066696 |
| MX1 | MX dynamin-like GTPase 1 | -0.0625403 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0567201 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0564389 |
| RPS2 | ribosomal protein S2 | -0.0549116 |
| RIGI | RNA sensor RIG-I | -0.0522034 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0497132 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0469446 |
| GLIS3 | GLIS family zinc finger 3 | -0.0469246 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0463032 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0461772 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0459023 |
| POTEF | POTE ankyrin domain family, member F | -0.0458102 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0454004 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0448043 |
| KYNU | kynureninase | -0.0445474 |
| FTL | ferritin, light polypeptide | -0.0414694 |
| RAI14 | retinoic acid induced 14 | -0.0393664 |
| CP | ceruloplasmin (ferroxidase) | -0.0382945 |
| CENPF | centromere protein F, 350/400kDa | -0.0374266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.037099 |
| RNF213 | ring finger protein 213 | -0.0358205 |
| NRP2 | neuropilin 2 | -0.0357346 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0355529 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0353491 |
| RPS6 | ribosomal protein S6 | -0.0349362 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0335989 |
| OSMR | oncostatin M receptor | -0.0335303 |
| SP100 | SP100 nuclear antigen | -0.033398 |
| SLFN5 | schlafen family member 5 | -0.0311966 |
| HMGB1 | high mobility group box 1 | -0.0308942 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0305929 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0304922 |
| IFI44L | interferon-induced protein 44-like | -0.0304295 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0301993 |
| RPL38 | ribosomal protein L38 | -0.0301633 |
| CDCP1 | CUB domain containing protein 1 | -0.0287702 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0286408 |
| MAP1B | microtubule-associated protein 1B | -0.0281175 |
| XAF1 | XIAP associated factor 1 | -0.0280121 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0280072 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.027286 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0268821 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0259712 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0259543 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0254528 |
| EXOC4 | exocyst complex component 4 | -0.0251606 |
| RRM2 | ribonucleotide reductase M2 | -0.0249626 |
| TUSC3 | tumor suppressor candidate 3 | -0.0246804 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0244063 |
| RPL37A | ribosomal protein L37a | -0.0242312 |
| CREB5 | cAMP responsive element binding protein 5 | -0.023584 |
| RPS8 | ribosomal protein S8 | -0.0234779 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0227813 |
| DGKI | diacylglycerol kinase, iota | -0.0227741 |
| S100A10 | S100 calcium binding protein A10 | -0.0227516 |
| TUBA1B | tubulin, alpha 1b | -0.0225978 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0220688 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0219773 |
| IL6 | interleukin 6 | -0.0215493 |
| IFI44 | interferon-induced protein 44 | -0.0214137 |
| SQSTM1 | sequestosome 1 | -0.0212364 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0212261 |
| RPL12 | ribosomal protein L12 | -0.0211537 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0210399 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0207239 |
| VCAN | versican | -0.0206074 |
| MTAP | methylthioadenosine phosphorylase | -0.0205462 |
| DOCK10 | dedicator of cytokinesis 10 | -0.0200427 |
| TLN1 | talin 1 | -0.0198639 |
| MT2A | metallothionein 2A | -0.01978 |
| NLGN1 | neuroligin 1 | -0.0197259 |
| EGR1 | early growth response 1 | -0.0194347 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0193156 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0192283 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.019194 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0190474 |
| NAV3 | neuron navigator 3 | -0.0189713 |
| RPLP1 | ribosomal protein, large, P1 | -0.0189357 |
| PTGR1 | prostaglandin reductase 1 | -0.0189034 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0187502 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0185012 |
| ANLN | anillin, actin binding protein | -0.0183338 |
| EHBP1 | EH domain binding protein 1 | -0.0182073 |
| RPL19 | ribosomal protein L19 | -0.0178959 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0177185 |
| JUN | jun proto-oncogene | -0.0176686 |
| TRIM56 | tripartite motif containing 56 | -0.0173771 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0172852 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0172524 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0171695 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0171657 |
| DSG2 | desmoglein 2 | -0.0171388 |
| HLA-B | major histocompatibility complex, class I, B | -0.0171033 |
