| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.154715 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.106307 |
| PTMA | prothymosin, alpha | 0.100017 |
| MGP | matrix Gla protein | 0.09858 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.07678 |
| B2M | beta-2-microglobulin | 0.0650369 |
| MT2A | metallothionein 2A | 0.0643025 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0642626 |
| RPS12 | ribosomal protein S12 | 0.0617906 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0608402 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0606786 |
| RPS6 | ribosomal protein S6 | 0.0601716 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0598699 |
| IER3 | immediate early response 3 | 0.0592333 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0579215 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.057556 |
| ENO1 | enolase 1, (alpha) | 0.0566142 |
| PGK1 | phosphoglycerate kinase 1 | 0.053796 |
| CALR | calreticulin | 0.0520205 |
| RPLP1 | ribosomal protein, large, P1 | 0.0517095 |
| UBC | ubiquitin C | 0.0513182 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0483008 |
| RACK1 | receptor for activated C kinase 1 | 0.0481512 |
| RPL23 | ribosomal protein L23 | 0.047818 |
| RPS19 | ribosomal protein S19 | 0.0454107 |
| RPL19 | ribosomal protein L19 | 0.0435639 |
| FLNB | filamin B, beta | 0.0427928 |
| RPS3 | ribosomal protein S3 | 0.0399432 |
| RPS13 | ribosomal protein S13 | 0.0398578 |
| TMSB4X | thymosin beta 4, X-linked | 0.0395617 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0393469 |
| TPI1 | triosephosphate isomerase 1 | 0.0391176 |
| RPS8 | ribosomal protein S8 | 0.0388068 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0383101 |
| ASPH | aspartate beta-hydroxylase | 0.03818 |
| RPL26 | ribosomal protein L26 | 0.0374829 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0374063 |
| RPL7A | ribosomal protein L7a | 0.0370671 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0356543 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0355572 |
| RBM39 | RNA binding motif protein 39 | 0.0352167 |
| FNIP1 | folliculin interacting protein 1 | 0.0350386 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0345373 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0345119 |
| RPL11 | ribosomal protein L11 | 0.0343788 |
| RPS23 | ribosomal protein S23 | 0.0342415 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0341395 |
| DST | dystonin | 0.0341232 |
| MCL1 | myeloid cell leukemia 1 | 0.0339928 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0337415 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0331934 |
| S100A9 | S100 calcium binding protein A9 | 0.0324132 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0323671 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0322986 |
| LAMA4 | laminin, alpha 4 | 0.0322931 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0320319 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0317444 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0317424 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.031726 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0317127 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0314066 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0312675 |
| CCNL1 | cyclin L1 | 0.0312393 |
| SQSTM1 | sequestosome 1 | 0.0312175 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310301 |
| RPLP0 | ribosomal protein, large, P0 | 0.0308331 |
| INSIG2 | insulin induced gene 2 | 0.030619 |
| XPO1 | exportin 1 | 0.0302875 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0300006 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0296664 |
| RPL31 | ribosomal protein L31 | 0.0295034 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0294349 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0289112 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0288221 |
| NDRG1 | N-myc downstream regulated 1 | 0.0287339 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0286229 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.028612 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0284055 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0283988 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0280333 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0280045 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0279449 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0277926 |
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.0274446 |
| CCNG2 | cyclin G2 | 0.0272389 |
| OXSR1 | oxidative stress responsive 1 | 0.0270003 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0268495 |
| SETD5 | SET domain containing 5 | 0.0267597 |
| HELZ | helicase with zinc finger | 0.0266464 |
| RPLP2 | ribosomal protein, large, P2 | 0.0265655 |
| LMO7 | LIM domain 7 | 0.0265127 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0264373 |
| FN1 | fibronectin 1 | 0.026067 |
| MED13 | mediator complex subunit 13 | 0.0260085 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259485 |
| RPL12 | ribosomal protein L12 | 0.0259458 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0259001 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0258643 |
| LDHA | lactate dehydrogenase A | 0.0258456 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0258195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.156038 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.142707 |
| HMGA2 | high mobility group AT-hook 2 | -0.102792 |
| CADM2 | cell adhesion molecule 2 | -0.102792 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0948438 |
| MEOX2 | mesenchyme homeobox 2 | -0.0868126 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0660036 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.065779 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0653184 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0644896 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0641029 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0598942 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.058395 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0580968 |
| RANBP17 | RAN binding protein 17 | -0.0562638 |
| SEPTIN11 | septin 11 | -0.0532706 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0502253 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0447105 |
| PCDH7 | protocadherin 7 | -0.0428391 |
| BCOR | BCL6 corepressor | -0.0423823 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0423146 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0421145 |
| TCF12 | transcription factor 12 | -0.0414144 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0410825 |
| SHROOM3 | shroom family member 3 | -0.0403236 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0391645 |
| PHF14 | PHD finger protein 14 | -0.0391301 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0368446 |
| NBEA | neurobeachin | -0.035968 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0356245 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0350485 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0349329 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0347848 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0345474 |
| NFIB | nuclear factor I/B | -0.0342394 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0338381 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0337412 |
| PDGFC | platelet derived growth factor C | -0.0330015 |
| FBXO11 | F-box protein 11 | -0.0329915 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0328629 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0326483 |
| ATG10 | autophagy related 10 | -0.0322903 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0322629 |
| RNF130 | ring finger protein 130 | -0.031814 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0317197 |
| CDK6 | cyclin-dependent kinase 6 | -0.0313019 |
| MATR3 | matrin 3 | -0.0312301 |
| NFIA | nuclear factor I/A | -0.0312204 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.031136 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0308341 |
| HDAC8 | histone deacetylase 8 | -0.0305115 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0302351 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.030231 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0300561 |
| BOC | BOC cell adhesion associated, oncogene regulated | -0.0298435 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0297983 |
| KAZN | kazrin, periplakin interacting protein | -0.029218 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0289343 |
| PARVA | parvin, alpha | -0.028271 |
| KIAA1328 | KIAA1328 | -0.0272151 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.02717 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0268213 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0267409 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0267288 |
| PCM1 | pericentriolar material 1 | -0.026509 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0263739 |
| WDR27 | WD repeat domain 27 | -0.0260986 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0259778 |
| CUX1 | cut-like homeobox 1 | -0.025919 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.025712 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.025375 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0252917 |
| RAD51B | RAD51 paralog B | -0.0251025 |
| VCL | vinculin | -0.0248964 |
| USP47 | ubiquitin specific peptidase 47 | -0.0248521 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0245799 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0245533 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -0.0245455 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0243311 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0241178 |
| ATAD2B | ATPase family, AAA domain containing 2B | -0.0239364 |
| LYPD6 | LY6/PLAUR domain containing 6 | -0.0235493 |
| WDR70 | WD repeat domain 70 | -0.023444 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0230555 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0229509 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0228289 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0228266 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0228191 |
| JMJD1C | jumonji domain containing 1C | -0.0227657 |
| PKP4 | plakophilin 4 | -0.0227185 |
| EXOC4 | exocyst complex component 4 | -0.0227072 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | -0.0225895 |
| LATS2 | large tumor suppressor kinase 2 | -0.0224326 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0224255 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0223294 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0221118 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0219799 |
| WWOX | WW domain containing oxidoreductase | -0.0219204 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0218905 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.021884 |
