| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.330028 |
| LAMB3 | laminin, beta 3 | 0.314436 |
| FLNB | filamin B, beta | 0.166723 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.1316 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.131254 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.120597 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.120576 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.106636 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.100709 |
| KLK10 | kallikrein-related peptidase 10 | 0.0997722 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0961205 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0959577 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0867604 |
| LAMC2 | laminin, gamma 2 | 0.0800546 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0733379 |
| MCL1 | myeloid cell leukemia 1 | 0.0714916 |
| ACTN4 | actinin, alpha 4 | 0.0699379 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0678639 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0662767 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0639976 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0620681 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0602358 |
| MXD1 | MAX dimerization protein 1 | 0.0594936 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0594637 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0559709 |
| PARD3 | par-3 family cell polarity regulator | 0.0542537 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.053719 |
| MUC17 | mucin 17, cell surface associated | 0.0532629 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0499209 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0497636 |
| TJP1 | tight junction protein 1 | 0.0485572 |
| CAPRIN2 | caprin family member 2 | 0.0479961 |
| VCL | vinculin | 0.0476581 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0471434 |
| UBC | ubiquitin C | 0.0469762 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0457751 |
| RASAL2 | RAS protein activator like 2 | 0.045491 |
| MSN | moesin | 0.0447818 |
| RCOR1 | REST corepressor 1 | 0.0441879 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0433508 |
| UPP1 | uridine phosphorylase 1 | 0.0430607 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0425789 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0421815 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0418122 |
| DIAPH1 | diaphanous-related formin 1 | 0.0417234 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0416908 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0413341 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0408904 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0402217 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0398462 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0397439 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0388618 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0385398 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.037479 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0372946 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.037281 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0371526 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0363804 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.036034 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0358212 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0355241 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0351682 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0348908 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0348587 |
| SLMAP | sarcolemma associated protein | 0.0346215 |
| OXSR1 | oxidative stress responsive 1 | 0.0345 |
| CORO1C | coronin, actin binding protein, 1C | 0.0343553 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.034015 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.03399 |
| SEPTIN10 | septin 10 | 0.0339321 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0336828 |
| FAM3C | family with sequence similarity 3, member C | 0.0336516 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0336343 |
| SREK1IP1 | SREK1-interacting protein 1 | 0.0336157 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0324704 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0321874 |
| SNX9 | sorting nexin 9 | 0.0321417 |
| TMEM41B | transmembrane protein 41B | 0.032139 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0320962 |
| ARF4 | ADP-ribosylation factor 4 | 0.0315669 |
| FOXO3 | forkhead box O3 | 0.0312912 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0311683 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0308821 |
| RTN4 | reticulon 4 | 0.0304687 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.030296 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0302857 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0301215 |
| RIOK3 | RIO kinase 3 | 0.0300671 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0299034 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0296333 |
| B2M | beta-2-microglobulin | 0.0295699 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.029561 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0289443 |
| GOLGA4 | golgin A4 | 0.0288912 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.0288888 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.028575 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0275497 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0273109 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0270769 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.026955 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCAN | versican | -0.0984336 |
| TMSB10 | thymosin beta 10 | -0.0784928 |
| S100A10 | S100 calcium binding protein A10 | -0.0738488 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0723521 |
| SQSTM1 | sequestosome 1 | -0.0651802 |
| AHNAK | AHNAK nucleoprotein | -0.0649601 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.063152 |
| NDRG1 | N-myc downstream regulated 1 | -0.062489 |
| DSG2 | desmoglein 2 | -0.0610255 |
| MYOF | myoferlin | -0.0602247 |
| ASPH | aspartate beta-hydroxylase | -0.0578567 |
| PTMA | prothymosin, alpha | -0.0536832 |
| EFNA5 | ephrin-A5 | -0.0522378 |
| RPS2 | ribosomal protein S2 | -0.051762 |
| PRELID2 | PRELI domain containing 2 | -0.0504617 |
| RPS3 | ribosomal protein S3 | -0.0481912 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0466041 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0443534 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0439389 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0428554 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0426172 |
| MATR3 | matrin 3 | -0.0411333 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0406829 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.038628 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0386214 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.036459 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0362572 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0355566 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0355158 |
| SMAD3 | SMAD family member 3 | -0.0353291 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0351065 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0350021 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0347113 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0343516 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0342521 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0341778 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0327392 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0322949 |
| RPS12 | ribosomal protein S12 | -0.030481 |
| IER3 | immediate early response 3 | -0.0301803 |
| RIN2 | Ras and Rab interactor 2 | -0.0289718 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.028752 |
| HPCAL1 | hippocalcin-like 1 | -0.0286461 |
| POTEF | POTE ankyrin domain family, member F | -0.0285465 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0281674 |
| EHBP1 | EH domain binding protein 1 | -0.0280192 |
| ANLN | anillin, actin binding protein | -0.0276026 |
| PLAC8 | placenta-specific 8 | -0.0273781 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0272795 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0268719 |
| ANXA2 | annexin A2 | -0.0265891 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0261221 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0258292 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0257873 |
| NEK7 | NIMA-related kinase 7 | -0.0254725 |
| RIGI | RNA sensor RIG-I | -0.0252138 |
| RPL12 | ribosomal protein L12 | -0.0251287 |
| ANXA4 | annexin A4 | -0.0250211 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0249829 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.024868 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0242924 |
| TMEM123 | transmembrane protein 123 | -0.0242917 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0242403 |
| SLC35F3 | solute carrier family 35, member F3 | -0.024112 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | -0.0239525 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0238894 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0238358 |
| DST | dystonin | -0.0238238 |
| PKM | pyruvate kinase, muscle | -0.023556 |
| ATXN1 | ataxin 1 | -0.0233345 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.0231291 |
| SERTAD2 | SERTA domain containing 2 | -0.0229008 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0228681 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0225172 |
| FAT1 | FAT atypical cadherin 1 | -0.0223459 |
| DIAPH2 | diaphanous-related formin 2 | -0.0223042 |
| KRT19 | keratin 19, type I | -0.0221 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0220359 |
| TOP1 | topoisomerase (DNA) I | -0.0218943 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0217094 |
| RPS23 | ribosomal protein S23 | -0.0215356 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0213105 |
| RPS8 | ribosomal protein S8 | -0.0212935 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0212677 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0211026 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0209814 |
| SDC4 | syndecan 4 | -0.0209531 |
| HMGA2 | high mobility group AT-hook 2 | -0.0207109 |
| ZFR | zinc finger RNA binding protein | -0.0207088 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0205656 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02055 |
| PON2 | paraoxonase 2 | -0.0204283 |
| PCBP2 | poly(rC) binding protein 2 | -0.0201555 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0201489 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0200544 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -0.0199798 |
| ITGB4 | integrin, beta 4 | -0.0199733 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0197536 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.019706 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0196965 |
