| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.16349 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.102344 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0947091 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0788881 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0771978 |
| LDHA | lactate dehydrogenase A | 0.0711517 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0680585 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0625244 |
| NEBL | nebulette | 0.0606812 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0575458 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0562067 |
| RPL11 | ribosomal protein L11 | 0.0557192 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0544592 |
| PGK1 | phosphoglycerate kinase 1 | 0.0540323 |
| NGLY1 | N-glycanase 1 | 0.0530905 |
| SMYD3 | SET and MYND domain containing 3 | 0.0503913 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0499136 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0491979 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0481933 |
| ZNF292 | zinc finger protein 292 | 0.045853 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0452507 |
| OGA | O-GlcNAcase | 0.0450277 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.044892 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0444938 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0441666 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0440168 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0439531 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0435656 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0433359 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0431583 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.042838 |
| RPS6 | ribosomal protein S6 | 0.0426199 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0419508 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0418026 |
| RPS8 | ribosomal protein S8 | 0.0414779 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0411179 |
| NFIA | nuclear factor I/A | 0.0410249 |
| RPS13 | ribosomal protein S13 | 0.0408461 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0407408 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0405587 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0402877 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0397836 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0396822 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0392707 |
| VMP1 | vacuole membrane protein 1 | 0.0390143 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0378416 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0378113 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0376914 |
| RPL7 | ribosomal protein L7 | 0.0370996 |
| PHIP | pleckstrin homology domain interacting protein | 0.0367681 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0366757 |
| FMNL2 | formin-like 2 | 0.0365345 |
| MED13 | mediator complex subunit 13 | 0.0365015 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0364902 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0364343 |
| ATP11A | ATPase, class VI, type 11A | 0.0362822 |
| FOXO3 | forkhead box O3 | 0.0347383 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0346632 |
| ATRN | attractin | 0.0342073 |
| ENO1 | enolase 1, (alpha) | 0.0341798 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0339489 |
| TPI1 | triosephosphate isomerase 1 | 0.0338206 |
| RPL13A | ribosomal protein L13a | 0.0336394 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0336111 |
| VIM | vimentin | 0.0335412 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0332832 |
| RPL5 | ribosomal protein L5 | 0.0329145 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.03277 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0326243 |
| RPS27A | ribosomal protein S27a | 0.0316871 |
| SBF2 | SET binding factor 2 | 0.0315036 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0314574 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0312111 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0306014 |
| KIAA1958 | KIAA1958 | 0.0305952 |
| RPL31 | ribosomal protein L31 | 0.0305417 |
| CABIN1 | calcineurin binding protein 1 | 0.0301803 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0301352 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0299756 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0295974 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0294808 |
| RNF150 | ring finger protein 150 | 0.0294508 |
| SLMAP | sarcolemma associated protein | 0.0294234 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0294187 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0293167 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0292755 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0291531 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0290889 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0289968 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0288501 |
| RPL30 | ribosomal protein L30 | 0.0286819 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0286572 |
| ARFGEF3 | ARFGEF family member 3 | 0.0284442 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0283887 |
| TPD52 | tumor protein D52 | 0.0283636 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.0282754 |
| RPS12 | ribosomal protein S12 | 0.0282035 |
| NUP58 | nucleoporin 58 | 0.0281564 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0281269 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0277978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.224338 |
| CADM2 | cell adhesion molecule 2 | -0.108008 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0839212 |
| RAD51B | RAD51 paralog B | -0.0722664 |
| TENM3 | teneurin transmembrane protein 3 | -0.0544409 |
| CDH18 | cadherin 18, type 2 | -0.0526589 |
| RIGI | RNA sensor RIG-I | -0.0468636 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0442906 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0398227 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0391389 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0356228 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0351527 |
| BNC2 | basonuclin 2 | -0.0347846 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0321215 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0310492 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.030503 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0278861 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0278144 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0268666 |
| TMEM178B | transmembrane protein 178B | -0.0266232 |
| CENPF | centromere protein F, 350/400kDa | -0.0264819 |
| RPL38 | ribosomal protein L38 | -0.0261286 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0260754 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0251217 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.02448 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0242778 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0240358 |
| EMP1 | epithelial membrane protein 1 | -0.0236383 |
| DCDC2 | doublecortin domain containing 2 | -0.0235323 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0229622 |
| ANXA2 | annexin A2 | -0.0227819 |
| PPHLN1 | periphilin 1 | -0.0216066 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0212244 |
| RBM28 | RNA binding motif protein 28 | -0.0211145 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0210989 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0208463 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0206135 |
| EXOC4 | exocyst complex component 4 | -0.0204697 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0203722 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.019863 |
| TPX2 | TPX2, microtubule-associated | -0.0196823 |
| HMGB1 | high mobility group box 1 | -0.0196637 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0195869 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | -0.0195646 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0194819 |
| MLIP | muscular LMNA-interacting protein | -0.019422 |
| C1ORF159 | chromosome 1 open reading frame 159 | -0.0193942 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0192214 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0191311 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0190188 |
| TCF12 | transcription factor 12 | -0.0186741 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0184311 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -0.0184167 |
| NOP56 | NOP56 ribonucleoprotein | -0.0183633 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0183545 |
| CLINT1 | clathrin interactor 1 | -0.0181467 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0179368 |
| TMEM259 | transmembrane protein 259 | -0.0178394 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0175838 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0175023 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0173514 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0172979 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0171718 |
| KIAA1671 | KIAA1671 | -0.0171113 |
| SETX | senataxin | -0.0168362 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0167722 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0163244 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0162466 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0161925 |
| NAF1 | nuclear assembly factor 1 ribonucleoprotein | -0.0161013 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0160945 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0160425 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0158811 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0158749 |
| HDAC4 | histone deacetylase 4 | -0.0158702 |
| PMP22 | peripheral myelin protein 22 | -0.0157274 |
| DIAPH2 | diaphanous-related formin 2 | -0.0152666 |
| TMEM117 | transmembrane protein 117 | -0.0152482 |
| STX8 | syntaxin 8 | -0.0152179 |
| FTO | fat mass and obesity associated | -0.0150399 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0150077 |
| CENPE | centromere protein E, 312kDa | -0.0149932 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0148162 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.0147126 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0146807 |
| NDRG1 | N-myc downstream regulated 1 | -0.014658 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0146048 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0145703 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0144595 |
| PCNX4 | pecanex 4 | -0.0143952 |
| ZNRF3 | zinc and ring finger 3 | -0.0142152 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0140438 |
| EP400 | E1A binding protein p400 | -0.0140015 |
| RGS12 | regulator of G-protein signaling 12 | -0.0139813 |
| MYO9A | myosin IXA | -0.0139665 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0139109 |
| NID1 | nidogen 1 | -0.0139024 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0139005 |
| SNW1 | SNW domain containing 1 | -0.0138817 |
| RPS2 | ribosomal protein S2 | -0.0138166 |
