| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.121123 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.113731 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.10202 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.097069 |
| CD109 | CD109 molecule | 0.090043 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0855812 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0839886 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0810796 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0771975 |
| PRELID2 | PRELI domain containing 2 | 0.0653163 |
| NBAS | neuroblastoma amplified sequence | 0.0651302 |
| PHF21A | PHD finger protein 21A | 0.0642973 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0638044 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0628997 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0617081 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0598874 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.059184 |
| FMNL2 | formin-like 2 | 0.058505 |
| PTK2 | protein tyrosine kinase 2 | 0.0579321 |
| CABIN1 | calcineurin binding protein 1 | 0.0556331 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0539954 |
| NDRG1 | N-myc downstream regulated 1 | 0.0521631 |
| RFX7 | regulatory factor X, 7 | 0.0511062 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0500487 |
| SETD5 | SET domain containing 5 | 0.0488982 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.048775 |
| CTTNBP2 | cortactin binding protein 2 | 0.0478578 |
| GOLGA4 | golgin A4 | 0.047841 |
| NUP58 | nucleoporin 58 | 0.0472468 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.047049 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0462152 |
| NAV2 | neuron navigator 2 | 0.0461785 |
| SRPK2 | SRSF protein kinase 2 | 0.0459084 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.04546 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0444626 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0435576 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0426295 |
| S100A6 | S100 calcium binding protein A6 | 0.0418725 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0415084 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0409533 |
| CENPF | centromere protein F, 350/400kDa | 0.0406227 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0399426 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0392749 |
| ATXN1 | ataxin 1 | 0.0381884 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0379198 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0375741 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0374777 |
| CDK8 | cyclin-dependent kinase 8 | 0.0367054 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0366582 |
| POM121 | POM121 transmembrane nucleoporin | 0.0365578 |
| OGA | O-GlcNAcase | 0.0364437 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0362413 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0359273 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0356879 |
| INSIG1 | insulin induced gene 1 | 0.0347299 |
| TMEM178B | transmembrane protein 178B | 0.0344293 |
| KDM2B | lysine (K)-specific demethylase 2B | 0.033619 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0332091 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.032958 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0329146 |
| COPA | coatomer protein complex, subunit alpha | 0.0328796 |
| ZC3H7A | zinc finger CCCH-type containing 7A | 0.0328578 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0319225 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0319033 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0318422 |
| ZYX | zyxin | 0.0318322 |
| HELZ | helicase with zinc finger | 0.0313085 |
| MT2A | metallothionein 2A | 0.0305771 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0301587 |
| RNF145 | ring finger protein 145 | 0.0300535 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0297041 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0295602 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0295185 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | 0.0293306 |
| ZNF292 | zinc finger protein 292 | 0.0292973 |
| INSIG2 | insulin induced gene 2 | 0.0291361 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0290718 |
| PARVB | parvin, beta | 0.0289666 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0288863 |
| CDK19 | cyclin-dependent kinase 19 | 0.0287893 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0286348 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0285641 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.027989 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0278789 |
| YAP1 | Yes-associated protein 1 | 0.0274207 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0271062 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0270857 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0270737 |
| SNX14 | sorting nexin 14 | 0.0268722 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0267921 |
| GPC6 | glypican 6 | 0.026694 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.02668 |
| FOXJ3 | forkhead box J3 | 0.0264232 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0264127 |
| CLMN | calmin (calponin-like, transmembrane) | 0.026364 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0262003 |
| TBK1 | TANK-binding kinase 1 | 0.0261968 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0258552 |
| RNF150 | ring finger protein 150 | 0.02535 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0252418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.136314 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0909507 |
| FMN1 | formin 1 | -0.0879109 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0760093 |
| HMCN1 | hemicentin 1 | -0.0677848 |
| FN1 | fibronectin 1 | -0.0544173 |
| FRMD4A | FERM domain containing 4A | -0.0493768 |
| NAV3 | neuron navigator 3 | -0.0483613 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0467789 |
| RHEB | Ras homolog enriched in brain | -0.0451692 |
| FRMD5 | FERM domain containing 5 | -0.0445515 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0439123 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0424672 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0406503 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0387516 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0381068 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0376348 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0374469 |
| AHNAK | AHNAK nucleoprotein | -0.0372341 |
| IFRD1 | interferon-related developmental regulator 1 | -0.036666 |
| VIM | vimentin | -0.0363827 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0358406 |
| EMP1 | epithelial membrane protein 1 | -0.0349752 |
| PAX3 | paired box 3 | -0.0346317 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.034166 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0340387 |
| EHBP1 | EH domain binding protein 1 | -0.0339904 |
| EGR1 | early growth response 1 | -0.0338832 |
| MACROD2 | MACRO domain containing 2 | -0.0334722 |
| RLF | rearranged L-myc fusion | -0.0333057 |
| RUNX1 | runt-related transcription factor 1 | -0.0327178 |
| IER3 | immediate early response 3 | -0.032671 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0314252 |
| NBEA | neurobeachin | -0.0307429 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.030631 |
| TMSB10 | thymosin beta 10 | -0.0300521 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.029568 |
| TLE4 | transducin-like enhancer of split 4 | -0.0292688 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0288864 |
| HBP1 | HMG-box transcription factor 1 | -0.028683 |
| TNNC1 | troponin C type 1 (slow) | -0.028111 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0275129 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0270522 |
| CDK14 | cyclin-dependent kinase 14 | -0.0268958 |
| TMEM263 | transmembrane protein 263 | -0.0268461 |
| OSMR | oncostatin M receptor | -0.0266987 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0266654 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0262799 |
| LRRC23 | leucine rich repeat containing 23 | -0.0256359 |
| ADM | adrenomedullin | -0.0253734 |
| BSG | basigin (Ok blood group) | -0.0243537 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0241605 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0240905 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0239286 |
| LAMB1 | laminin, beta 1 | -0.023663 |
| ATXN7L1 | ataxin 7-like 1 | -0.0236063 |
| LYST | lysosomal trafficking regulator | -0.0235436 |
| EBF1 | early B-cell factor 1 | -0.0233678 |
| TCF12 | transcription factor 12 | -0.0231643 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0230609 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0230544 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.023048 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0227257 |
| JAZF1 | JAZF zinc finger 1 | -0.0227021 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0225025 |
| FBXO32 | F-box protein 32 | -0.0221235 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0216689 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.0210611 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0208016 |
| FAM53C | family with sequence similarity 53, member C | -0.0207263 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0206551 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0206132 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.0205332 |
| ACTG1 | actin gamma 1 | -0.0204693 |
| THBS2 | thrombospondin 2 | -0.0203221 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0202056 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 | -0.0201454 |
| PDE10A | phosphodiesterase 10A | -0.0200085 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0199686 |
| DMD | dystrophin | -0.0197769 |
| MITF | microphthalmia-associated transcription factor | -0.0196145 |
| TPI1 | triosephosphate isomerase 1 | -0.0195776 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0194914 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0192647 |
| AOPEP | aminopeptidase O (putative) | -0.0192521 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0191252 |
| NPR2 | natriuretic peptide receptor 2 | -0.0191215 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | -0.0190625 |
| NEK7 | NIMA-related kinase 7 | -0.0190376 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0190336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0188259 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0187737 |
| RANBP17 | RAN binding protein 17 | -0.0187661 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0187058 |
| INTS6 | integrator complex subunit 6 | -0.018562 |
| FHIT | fragile histidine triad | -0.0185254 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0184355 |
| RPLP1 | ribosomal protein, large, P1 | -0.0182054 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0181137 |
| SERINC5 | serine incorporator 5 | -0.0179195 |
