| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.171711 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.136354 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110865 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.110665 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.105033 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.105 |
| LAMC2 | laminin, gamma 2 | 0.09749 |
| MCL1 | myeloid cell leukemia 1 | 0.0972567 |
| UBC | ubiquitin C | 0.0841301 |
| SPAG9 | sperm associated antigen 9 | 0.0789396 |
| NDRG1 | N-myc downstream regulated 1 | 0.0724737 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0723134 |
| APP | amyloid beta (A4) precursor protein | 0.07165 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0712885 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0694202 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0683617 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0634553 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.063333 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.062734 |
| FLNB | filamin B, beta | 0.0624282 |
| B2M | beta-2-microglobulin | 0.0604097 |
| ASPH | aspartate beta-hydroxylase | 0.0589057 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0585755 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0583555 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0582989 |
| TMSB4X | thymosin beta 4, X-linked | 0.0580892 |
| RCOR1 | REST corepressor 1 | 0.0579118 |
| DTNA | dystrobrevin, alpha | 0.0578386 |
| ACTG1 | actin gamma 1 | 0.0558789 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0558547 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0556326 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0554864 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0542651 |
| PGK1 | phosphoglycerate kinase 1 | 0.0527367 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0525376 |
| PLAU | plasminogen activator, urokinase | 0.0492635 |
| VMP1 | vacuole membrane protein 1 | 0.0489249 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0486952 |
| SMAD3 | SMAD family member 3 | 0.0479318 |
| LMO7 | LIM domain 7 | 0.0472086 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0467834 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0455267 |
| EZR | ezrin | 0.0444259 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0443286 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0441947 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0437887 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0437647 |
| OPTN | optineurin | 0.0425638 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0425072 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0412392 |
| PHF3 | PHD finger protein 3 | 0.0408233 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0405532 |
| APOL1 | apolipoprotein L, 1 | 0.0398443 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0388026 |
| RBM39 | RNA binding motif protein 39 | 0.0382318 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0381273 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0376528 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0373949 |
| HELZ | helicase with zinc finger | 0.0373189 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0366823 |
| MCU | mitochondrial calcium uniporter | 0.0361925 |
| CLTC | clathrin, heavy chain (Hc) | 0.0360442 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0359819 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0348635 |
| MYO5B | myosin VB | 0.0347168 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0345849 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0339277 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0336013 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0333334 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0331158 |
| LDHA | lactate dehydrogenase A | 0.0327369 |
| CCNY | cyclin Y | 0.0326753 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0326503 |
| PTMA | prothymosin, alpha | 0.0324895 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0323286 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0322552 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0322143 |
| MYO1E | myosin IE | 0.0321645 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.032115 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0320225 |
| CD2AP | CD2-associated protein | 0.0319195 |
| SYNRG | synergin, gamma | 0.0318869 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318337 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0316899 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0313871 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0311603 |
| INSIG2 | insulin induced gene 2 | 0.0310661 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0306192 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0302955 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.029643 |
| SFTPA2 | surfactant protein A2 | 0.0294524 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0294477 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0293796 |
| PLEC | plectin | 0.0292882 |
| RIOK3 | RIO kinase 3 | 0.0291809 |
| ABI1 | abl-interactor 1 | 0.0291332 |
| CDC42 | cell division cycle 42 | 0.0287491 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0284121 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0283816 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0280928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124628 |
| TMSB10 | thymosin beta 10 | -0.0987045 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0683347 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0597915 |
| FTL | ferritin, light polypeptide | -0.0551187 |
| MMP7 | matrix metallopeptidase 7 | -0.050338 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0466605 |
| MT1X | metallothionein 1X | -0.0441354 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426019 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0386365 |
| RPL35A | ribosomal protein L35a | -0.0370012 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.03606 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0343332 |
| MT2A | metallothionein 2A | -0.0293249 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0292494 |
| KRT19 | keratin 19, type I | -0.0272577 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0254842 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0249297 |
| LCN2 | lipocalin 2 | -0.0242064 |
| PCDH7 | protocadherin 7 | -0.0240502 |
| POTEF | POTE ankyrin domain family, member F | -0.022368 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0221083 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0218893 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.021539 |
| RPS24 | ribosomal protein S24 | -0.0214298 |
| RNF213 | ring finger protein 213 | -0.0213137 |
| RPS6 | ribosomal protein S6 | -0.0209413 |
| MX2 | MX dynamin-like GTPase 2 | -0.0206543 |
| VIM | vimentin | -0.0206447 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0205753 |
| RPS19 | ribosomal protein S19 | -0.0200225 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0199611 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0198093 |
| TMEM123 | transmembrane protein 123 | -0.0197952 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0197686 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0195224 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0189381 |
| NRG3 | neuregulin 3 | -0.0187103 |
| RPS29 | ribosomal protein S29 | -0.0183624 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.018304 |
| BICC1 | BicC family RNA binding protein 1 | -0.0181403 |
| MX1 | MX dynamin-like GTPase 1 | -0.0180509 |
| RPS8 | ribosomal protein S8 | -0.0176853 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0174504 |
| RPL19 | ribosomal protein L19 | -0.0174153 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.016745 |
| USP3 | ubiquitin specific peptidase 3 | -0.0165175 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0164179 |
| EFNA5 | ephrin-A5 | -0.0163715 |
| HMGB1 | high mobility group box 1 | -0.0160631 |
| ENO1 | enolase 1, (alpha) | -0.0157886 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.015534 |
| YBX1 | Y box binding protein 1 | -0.0154407 |
| RPL12 | ribosomal protein L12 | -0.0152326 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0149483 |
| MUC4 | mucin 4, cell surface associated | -0.0148534 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0147782 |
| RPL23 | ribosomal protein L23 | -0.0147246 |
| RPS21 | ribosomal protein S21 | -0.0146532 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0145317 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0144398 |
| RIGI | RNA sensor RIG-I | -0.0141032 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0139054 |
| RPLP0 | ribosomal protein, large, P0 | -0.0138333 |
| S100A9 | S100 calcium binding protein A9 | -0.0137747 |
| IER3 | immediate early response 3 | -0.0135556 |
| OSMR | oncostatin M receptor | -0.0135537 |
| RPS14 | ribosomal protein S14 | -0.0134753 |
| GLIS3 | GLIS family zinc finger 3 | -0.0133983 |
| RPS23 | ribosomal protein S23 | -0.0133196 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0133072 |
| RPL35 | ribosomal protein L35 | -0.0132487 |
| LAP3 | leucine aminopeptidase 3 | -0.0132318 |
| PMP22 | peripheral myelin protein 22 | -0.0131025 |
| EGR1 | early growth response 1 | -0.0128353 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0128124 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.012706 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.012677 |
| RPS5 | ribosomal protein S5 | -0.0125453 |
| TMEM263 | transmembrane protein 263 | -0.0124621 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0124072 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0122238 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0121543 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0121272 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.012041 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0119995 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0119353 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0119008 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0118796 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0117364 |
| S100A10 | S100 calcium binding protein A10 | -0.0117296 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0116382 |
| NNMT | nicotinamide N-methyltransferase | -0.0115888 |
| RPS25 | ribosomal protein S25 | -0.0115599 |
| PFN1 | profilin 1 | -0.0115578 |
| RPS11 | ribosomal protein S11 | -0.0114789 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0114177 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0112777 |
| RPL37A | ribosomal protein L37a | -0.0112059 |
| FOSL1 | FOS-like antigen 1 | -0.0111054 |
