| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.106326 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0927111 |
| LSAMP | limbic system-associated membrane protein | 0.0782344 |
| NRG1 | neuregulin 1 | 0.0731766 |
| DST | dystonin | 0.0602977 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0567678 |
| VMP1 | vacuole membrane protein 1 | 0.0543527 |
| FMN1 | formin 1 | 0.0502267 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0458252 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0436968 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0422792 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0416512 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.04162 |
| MEIS2 | Meis homeobox 2 | 0.0402984 |
| PLAT | plasminogen activator, tissue | 0.0400515 |
| MSI2 | musashi RNA-binding protein 2 | 0.0395808 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0377674 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0357793 |
| CADM2 | cell adhesion molecule 2 | 0.0325074 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0312353 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0311636 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0306012 |
| KLHL13 | kelch-like family member 13 | 0.0291578 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0290459 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0285184 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0282283 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0271108 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0269426 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0269191 |
| GPC5 | glypican 5 | 0.0267922 |
| B2M | beta-2-microglobulin | 0.0266561 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0266124 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0264869 |
| NREP | neuronal regeneration related protein | 0.0264374 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0261504 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0261236 |
| TCF12 | transcription factor 12 | 0.0257764 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0256733 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0255942 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0251879 |
| SPAG9 | sperm associated antigen 9 | 0.0248926 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0247934 |
| PRKCA | protein kinase C, alpha | 0.0244987 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0242456 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0237525 |
| RNF213 | ring finger protein 213 | 0.0230752 |
| USP36 | ubiquitin specific peptidase 36 | 0.0227325 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0225814 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0225259 |
| AHR | aryl hydrocarbon receptor | 0.0224567 |
| SMAD3 | SMAD family member 3 | 0.0223991 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0223797 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0223452 |
| FRMD4A | FERM domain containing 4A | 0.0223228 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0221672 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0221017 |
| GAB2 | GRB2-associated binding protein 2 | 0.0219642 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0218251 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0217901 |
| CLTC | clathrin, heavy chain (Hc) | 0.0216914 |
| SEPTIN9 | septin 9 | 0.0215268 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0214473 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0214206 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0210941 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0210726 |
| RAD51B | RAD51 paralog B | 0.0210711 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0210233 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0208767 |
| SYT1 | synaptotagmin I | 0.0208349 |
| RO60 | Ro60, Y RNA binding protein | 0.0207586 |
| SIK2 | salt-inducible kinase 2 | 0.0206799 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0204238 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0204141 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0202737 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0199942 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0199546 |
| FLNB | filamin B, beta | 0.0197652 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0195301 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0194079 |
| USP34 | ubiquitin specific peptidase 34 | 0.019405 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0193994 |
| ANGPT1 | angiopoietin 1 | 0.0191638 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.019158 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0190984 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0190276 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0187291 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0185905 |
| ATP13A3 | ATPase type 13A3 | 0.0184944 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0183901 |
| SCG2 | secretogranin II | 0.0183391 |
| TRIM24 | tripartite motif containing 24 | 0.0182011 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0181177 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0180368 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.017964 |
| TMF1 | TATA element modulatory factor 1 | 0.017899 |
| PHF3 | PHD finger protein 3 | 0.0178918 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0178344 |
| AEBP2 | AE binding protein 2 | 0.0178275 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0176657 |
| NBAS | neuroblastoma amplified sequence | 0.0176479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.105673 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0709243 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0506627 |
| HELZ | helicase with zinc finger | -0.0355594 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0332484 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0332159 |
| DTNA | dystrobrevin, alpha | -0.0284863 |
| RPL35A | ribosomal protein L35a | -0.0283254 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0280574 |
| QKI | QKI, KH domain containing, RNA binding | -0.0280383 |
| RPLP1 | ribosomal protein, large, P1 | -0.0268217 |
| FAM13A | family with sequence similarity 13, member A | -0.0260631 |
| RPL23 | ribosomal protein L23 | -0.0260174 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0253933 |
| ZNF292 | zinc finger protein 292 | -0.0249015 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0246009 |
| RYBP | RING1 and YY1 binding protein | -0.0242887 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0232466 |
| TLK2 | tousled-like kinase 2 | -0.0228781 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022728 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0212211 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0211818 |
| RARA | retinoic acid receptor, alpha | -0.0211153 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0209921 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0207614 |
| CXXC5 | CXXC finger protein 5 | -0.0202899 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0201809 |
| WDR45B | WD repeat domain 45B | -0.0198895 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0195335 |
| FAM162A | family with sequence similarity 162, member A | -0.0193754 |
| FOXO3 | forkhead box O3 | -0.0192351 |
| TMSB10 | thymosin beta 10 | -0.0190028 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0188798 |
| EGR1 | early growth response 1 | -0.0187605 |
| ZNF148 | zinc finger protein 148 | -0.0185622 |
| LPIN1 | lipin 1 | -0.0183898 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0183559 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0179279 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0179132 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0178913 |
| NUP58 | nucleoporin 58 | -0.0178731 |
| SEPTIN7 | septin 7 | -0.0177265 |
| POTEF | POTE ankyrin domain family, member F | -0.0170322 |
| MEF2A | myocyte enhancer factor 2A | -0.0169649 |
| ZFP36 | ZFP36 ring finger protein | -0.0169071 |
| CCDC88A | coiled-coil domain containing 88A | -0.0164818 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0164146 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0162505 |
| KIAA1217 | KIAA1217 | -0.0161558 |
| YBX1 | Y box binding protein 1 | -0.0158345 |
| RPS6 | ribosomal protein S6 | -0.0157309 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0155914 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0152696 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0152293 |
| RREB1 | ras responsive element binding protein 1 | -0.0150971 |
| VIM | vimentin | -0.0150725 |
| PCBP2 | poly(rC) binding protein 2 | -0.0149247 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.0149047 |
| DIAPH1 | diaphanous-related formin 1 | -0.0146765 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0143328 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0141039 |
| RPS20 | ribosomal protein S20 | -0.0140123 |
| PER1 | period circadian clock 1 | -0.0138845 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0137803 |
| FBXO11 | F-box protein 11 | -0.0135708 |
| RTN4 | reticulon 4 | -0.0135531 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0135061 |
| WTAP | Wilms tumor 1 associated protein | -0.0134627 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0134587 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.013373 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.013319 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0132762 |
| IER3 | immediate early response 3 | -0.0132757 |
| TLE4 | transducin-like enhancer of split 4 | -0.0132323 |
| MSMO1 | methylsterol monooxygenase 1 | -0.013179 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0131189 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0131154 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0129868 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0129605 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0128854 |
| PHIP | pleckstrin homology domain interacting protein | -0.0127741 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0127071 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0126927 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0126701 |
| XPO1 | exportin 1 | -0.0126044 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0125486 |
| LMNA | lamin A/C | -0.012496 |
| PFN1 | profilin 1 | -0.0124565 |
| ZNF207 | zinc finger protein 207 | -0.0123436 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0122782 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0122155 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0121952 |
| PCDH10 | protocadherin 10 | -0.0120136 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0120035 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0119218 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0118972 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0118334 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0117985 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0117368 |
| HDAC5 | histone deacetylase 5 | -0.0116018 |
