| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.101562 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0999147 |
| ERBIN | erbb2 interacting protein | 0.0886943 |
| TXNIP | thioredoxin interacting protein | 0.0765263 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0688696 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0679647 |
| VMP1 | vacuole membrane protein 1 | 0.066573 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0643142 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0613397 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0599575 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0592631 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0583721 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0578431 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0576742 |
| IFNGR1 | interferon gamma receptor 1 | 0.0571667 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0567035 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0564046 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0555705 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0550685 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0548122 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0544477 |
| MLPH | melanophilin | 0.052206 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0514186 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.050349 |
| NDRG1 | N-myc downstream regulated 1 | 0.0498887 |
| PGK1 | phosphoglycerate kinase 1 | 0.0495759 |
| MYO10 | myosin X | 0.0475038 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0468189 |
| PTMA | prothymosin, alpha | 0.0459386 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0457787 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0456465 |
| SMAD3 | SMAD family member 3 | 0.0447634 |
| FAT1 | FAT atypical cadherin 1 | 0.0444237 |
| EPCAM | epithelial cell adhesion molecule | 0.0439709 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0427442 |
| RNF149 | ring finger protein 149 | 0.0419154 |
| STK24 | serine/threonine kinase 24 | 0.0417325 |
| MAP7 | microtubule-associated protein 7 | 0.0402953 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0395765 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0386359 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0382341 |
| ZNF292 | zinc finger protein 292 | 0.0380972 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0379567 |
| PRELID2 | PRELI domain containing 2 | 0.0377855 |
| SSH2 | slingshot protein phosphatase 2 | 0.0377516 |
| MSI2 | musashi RNA-binding protein 2 | 0.0376314 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0373274 |
| PHF3 | PHD finger protein 3 | 0.0372039 |
| KIF16B | kinesin family member 16B | 0.0370731 |
| SERINC5 | serine incorporator 5 | 0.0369645 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0366201 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.036275 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0360404 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0360199 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0359872 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0357555 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0357056 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0356258 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.035352 |
| ABHD2 | abhydrolase domain containing 2 | 0.0352656 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0352251 |
| H1-0 | H1.0 linker histone | 0.0345243 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0342939 |
| LIMA1 | LIM domain and actin binding 1 | 0.0342786 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0337289 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0334048 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0333983 |
| YAP1 | Yes-associated protein 1 | 0.0333315 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.033204 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0331747 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0331553 |
| CMIP | c-Maf inducing protein | 0.0331382 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0329134 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0328781 |
| ASPH | aspartate beta-hydroxylase | 0.0328252 |
| RBM39 | RNA binding motif protein 39 | 0.0326924 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0326482 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0320896 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0318543 |
| USP53 | ubiquitin specific peptidase 53 | 0.0317535 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.031501 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0315003 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0313877 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0311608 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0310205 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.03102 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0307542 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0307313 |
| PDZD8 | PDZ domain containing 8 | 0.0305076 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0303315 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0303188 |
| SP3 | Sp3 transcription factor | 0.0300043 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0299582 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0294633 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0293379 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0292222 |
| FOXO3 | forkhead box O3 | 0.0291474 |
| BCL2L1 | BCL2-like 1 | 0.0288466 |
| MEF2A | myocyte enhancer factor 2A | 0.0286864 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.028677 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.166791 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124209 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.103934 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.087414 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0706174 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.068474 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0660878 |
| EGR1 | early growth response 1 | -0.0620202 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0617485 |
| EZR | ezrin | -0.0608302 |
| IRF1 | interferon regulatory factor 1 | -0.0592534 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0540201 |
| RIGI | RNA sensor RIG-I | -0.0528882 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0508969 |
| AGR2 | anterior gradient 2 | -0.0483988 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0480356 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0475415 |
| MX2 | MX dynamin-like GTPase 2 | -0.0450856 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0445048 |
| SEC24D | SEC24 family member D | -0.0393845 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0393169 |
| MORF4L2 | mortality factor 4 like 2 | -0.0371969 |
| SP100 | SP100 nuclear antigen | -0.0371672 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0361799 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343153 |
| SQSTM1 | sequestosome 1 | -0.03342 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0333562 |
| TBC1D22A | TBC1 domain family, member 22A | -0.033274 |
| RPS19 | ribosomal protein S19 | -0.0330995 |
| LCN2 | lipocalin 2 | -0.0328861 |
| RPL12 | ribosomal protein L12 | -0.0328106 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0326849 |
| RRBP1 | ribosome binding protein 1 | -0.0326465 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0324751 |
| ANXA1 | annexin A1 | -0.0323136 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305022 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0299822 |
| S100A10 | S100 calcium binding protein A10 | -0.0297634 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0296016 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0292484 |
| HLA-C | major histocompatibility complex, class I, C | -0.0290465 |
| RPL35A | ribosomal protein L35a | -0.0280328 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0280055 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0273546 |
| HDLBP | high density lipoprotein binding protein | -0.0264773 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0263741 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0262307 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0261782 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0260488 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0258405 |
| CALR | calreticulin | -0.0256643 |
| DIAPH3 | diaphanous-related formin 3 | -0.0253031 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0251361 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0241455 |
| RNF213 | ring finger protein 213 | -0.0240174 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0239975 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0236007 |
| MX1 | MX dynamin-like GTPase 1 | -0.0235212 |
| RPL19 | ribosomal protein L19 | -0.0233305 |
| RPL34 | ribosomal protein L34 | -0.023298 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0227795 |
| RPS6 | ribosomal protein S6 | -0.0226651 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0226255 |
| INTS6 | integrator complex subunit 6 | -0.0225405 |
| LMO7 | LIM domain 7 | -0.0225398 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0224647 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0223427 |
| TMEM263 | transmembrane protein 263 | -0.0221617 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.022141 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0215263 |
| CANX | calnexin | -0.0213481 |
| RUNX1 | runt-related transcription factor 1 | -0.0207953 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.020634 |
| MECOM | MDS1 and EVI1 complex locus | -0.0204873 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0204111 |
| RTN3 | reticulon 3 | -0.0203122 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0202978 |
| APOL6 | apolipoprotein L, 6 | -0.020159 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0198692 |
| NCALD | neurocalcin delta | -0.0197244 |
| SURF4 | surfeit 4 | -0.0195658 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0195254 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0194737 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0194004 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0193059 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0192817 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0188638 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0188546 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.018817 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.018717 |
| HM13 | histocompatibility (minor) 13 | -0.0186403 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0184893 |
| RPS24 | ribosomal protein S24 | -0.0184328 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0182724 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0182464 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0181286 |
| MVB12A | multivesicular body subunit 12A | -0.0181059 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0179936 |
| PER2 | period circadian clock 2 | -0.017867 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.0177978 |
