| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.227341 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.210789 |
| NDRG1 | N-myc downstream regulated 1 | 0.136991 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.107965 |
| STC1 | stanniocalcin 1 | 0.0996571 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0864202 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0821534 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0807513 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0741535 |
| CALR | calreticulin | 0.0667749 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0665344 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0663053 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.064395 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0642561 |
| EGFR | epidermal growth factor receptor | 0.063424 |
| ZNF841 | zinc finger protein 841 | 0.0625012 |
| LOX | lysyl oxidase | 0.0624784 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0621026 |
| GOLGA4 | golgin A4 | 0.0620095 |
| GOLGB1 | golgin B1 | 0.0617586 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0616554 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0592296 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0592034 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0572978 |
| COL5A1 | collagen, type V, alpha 1 | 0.0546715 |
| HDAC9 | histone deacetylase 9 | 0.053941 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0530887 |
| CANX | calnexin | 0.0525427 |
| CALU | calumenin | 0.0520422 |
| INHBA | inhibin, beta A | 0.0512956 |
| ATP13A3 | ATPase type 13A3 | 0.0510031 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0503895 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0501297 |
| MSN | moesin | 0.0492369 |
| USP36 | ubiquitin specific peptidase 36 | 0.048833 |
| CLTC | clathrin, heavy chain (Hc) | 0.0468192 |
| COG5 | component of oligomeric golgi complex 5 | 0.0464983 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0462375 |
| FNIP1 | folliculin interacting protein 1 | 0.0454043 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0434753 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0432503 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0427368 |
| CADM1 | cell adhesion molecule 1 | 0.0424615 |
| SRP54 | signal recognition particle 54kDa | 0.0424036 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0415169 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0411979 |
| ASPH | aspartate beta-hydroxylase | 0.0409422 |
| YEATS2 | YEATS domain containing 2 | 0.0396192 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.039526 |
| DTNA | dystrobrevin, alpha | 0.0392115 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0390284 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0389091 |
| FOXJ3 | forkhead box J3 | 0.0386996 |
| APP | amyloid beta (A4) precursor protein | 0.0386287 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0386256 |
| TMEM39A | transmembrane protein 39A | 0.0385559 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0382065 |
| PGK1 | phosphoglycerate kinase 1 | 0.0375564 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0372315 |
| PMM2 | phosphomannomutase 2 | 0.0371262 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.03701 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0364286 |
| MT2A | metallothionein 2A | 0.0361925 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.036072 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0359743 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0358877 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0358207 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.03565 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0354972 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0354865 |
| GPR107 | G protein-coupled receptor 107 | 0.0350692 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0347278 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0346912 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0345243 |
| RNF216 | ring finger protein 216 | 0.0343697 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0343069 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.034159 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.0341087 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0337081 |
| CDK13 | cyclin-dependent kinase 13 | 0.03329 |
| TMEM41B | transmembrane protein 41B | 0.033132 |
| SBF2 | SET binding factor 2 | 0.0331141 |
| FAM13A | family with sequence similarity 13, member A | 0.032884 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0328512 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0327163 |
| NF1 | neurofibromin 1 | 0.0322786 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.03193 |
| SETD5 | SET domain containing 5 | 0.0318819 |
| CLINT1 | clathrin interactor 1 | 0.0313985 |
| PYGL | phosphorylase, glycogen, liver | 0.0313612 |
| CALD1 | caldesmon 1 | 0.0313477 |
| ACTN1 | actinin, alpha 1 | 0.0312903 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0312901 |
| GPR173 | G protein-coupled receptor 173 | 0.0307953 |
| SCFD2 | sec1 family domain containing 2 | 0.0307502 |
| RASA2 | RAS p21 protein activator 2 | 0.0306409 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0305753 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304769 |
| COPA | coatomer protein complex, subunit alpha | 0.0303447 |
| RPS13 | ribosomal protein S13 | 0.030256 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.126076 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0643628 |
| POTEF | POTE ankyrin domain family, member F | -0.059797 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0568058 |
| EGR1 | early growth response 1 | -0.0545055 |
| TXNRD1 | thioredoxin reductase 1 | -0.0513717 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0485328 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0465341 |
| MAP1B | microtubule-associated protein 1B | -0.0404174 |
| ANXA2 | annexin A2 | -0.0387908 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0381353 |
| NLGN1 | neuroligin 1 | -0.0372681 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.037265 |
| RPLP1 | ribosomal protein, large, P1 | -0.0355182 |
| CD44 | CD44 molecule (Indian blood group) | -0.0354953 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0336953 |
| AHR | aryl hydrocarbon receptor | -0.0320359 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0312935 |
| TPM4 | tropomyosin 4 | -0.031184 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0305603 |
| GLIS3 | GLIS family zinc finger 3 | -0.0300354 |
| YBX1 | Y box binding protein 1 | -0.0300062 |
| TMSB10 | thymosin beta 10 | -0.0292968 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0291778 |
| ATXN1 | ataxin 1 | -0.0283684 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0273462 |
| CENPF | centromere protein F, 350/400kDa | -0.027169 |
| ENO1 | enolase 1, (alpha) | -0.026839 |
| TUBB | tubulin, beta class I | -0.0261296 |
| VCL | vinculin | -0.0260648 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0259121 |
| PXDN | peroxidasin | -0.0255588 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0249798 |
| HLA-B | major histocompatibility complex, class I, B | -0.0241016 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0237331 |
| TUBA1B | tubulin, alpha 1b | -0.0234688 |
| STK17A | serine/threonine kinase 17a | -0.0226648 |
| RPS6 | ribosomal protein S6 | -0.0221963 |
| GNAS | GNAS complex locus | -0.0221896 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0221637 |
| S100A10 | S100 calcium binding protein A10 | -0.0221588 |
| SQSTM1 | sequestosome 1 | -0.0220358 |
| VEGFA | vascular endothelial growth factor A | -0.0217357 |
| ACTG1 | actin gamma 1 | -0.0214882 |
| HMGB1 | high mobility group box 1 | -0.0212415 |
| RPL35A | ribosomal protein L35a | -0.0209264 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0204104 |
| SYT1 | synaptotagmin I | -0.0202298 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0201179 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0195748 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0194117 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0192821 |
| CCDC102B | coiled-coil domain containing 102B | -0.0191331 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.018777 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0186781 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0183691 |
| TMEM123 | transmembrane protein 123 | -0.0180955 |
| NAV3 | neuron navigator 3 | -0.0176709 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0174428 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0173495 |
| OSMR | oncostatin M receptor | -0.0171823 |
| RPL35 | ribosomal protein L35 | -0.0169299 |
| PALLD | palladin, cytoskeletal associated protein | -0.0168811 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0167816 |
| PRDX1 | peroxiredoxin 1 | -0.0167567 |
| BSG | basigin (Ok blood group) | -0.016741 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0165879 |
| CBX3 | chromobox homolog 3 | -0.0163156 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0162943 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0162679 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0161571 |
| PKM | pyruvate kinase, muscle | -0.0159112 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0157924 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0157164 |
| PTGR1 | prostaglandin reductase 1 | -0.0155938 |
| ZNF804A | zinc finger protein 804A | -0.0155375 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0155094 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0154915 |
| CTSD | cathepsin D | -0.0153891 |
| FOSL1 | FOS-like antigen 1 | -0.0152969 |
| RIGI | RNA sensor RIG-I | -0.015279 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0152582 |
| HIP1 | huntingtin interacting protein 1 | -0.015215 |
| DEK | DEK proto-oncogene | -0.0151798 |
| TTYH3 | tweety family member 3 | -0.0151295 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0151047 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0149183 |
| RPS8 | ribosomal protein S8 | -0.0148673 |
| MAP4 | microtubule-associated protein 4 | -0.0148205 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0146016 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0144998 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0144915 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0144755 |
| RPS20 | ribosomal protein S20 | -0.0144061 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0143232 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0141595 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0141181 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0141036 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0140858 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0139728 |
