| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | 0.12989 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.128703 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.101209 |
| GOLGA4 | golgin A4 | 0.0981872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0870723 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0763068 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0741521 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0716498 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0690392 |
| ARF4 | ADP-ribosylation factor 4 | 0.0676473 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0671037 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0666736 |
| PRELID2 | PRELI domain containing 2 | 0.066169 |
| MCL1 | myeloid cell leukemia 1 | 0.0654088 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0633191 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0606863 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0587177 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0582316 |
| FTL | ferritin, light polypeptide | 0.0575264 |
| ZNF638 | zinc finger protein 638 | 0.0573812 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0569478 |
| YEATS2 | YEATS domain containing 2 | 0.0565877 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0564995 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0545863 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0545816 |
| OGA | O-GlcNAcase | 0.0540643 |
| TMF1 | TATA element modulatory factor 1 | 0.0537456 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0527228 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0507244 |
| FDPS | farnesyl diphosphate synthase | 0.0502285 |
| VMP1 | vacuole membrane protein 1 | 0.0501762 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.049919 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0495405 |
| RBM39 | RNA binding motif protein 39 | 0.0491391 |
| NF1 | neurofibromin 1 | 0.0481102 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0470359 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0464099 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0463621 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0463378 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0461582 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0453324 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0452979 |
| TMEM41B | transmembrane protein 41B | 0.0447155 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0446244 |
| CDK19 | cyclin-dependent kinase 19 | 0.0438868 |
| COPA | coatomer protein complex, subunit alpha | 0.0436198 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0434772 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0431508 |
| SQSTM1 | sequestosome 1 | 0.043094 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.042722 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0419065 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0417592 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0417089 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.041672 |
| ZNF292 | zinc finger protein 292 | 0.041402 |
| SETD5 | SET domain containing 5 | 0.0411501 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0410252 |
| INSIG2 | insulin induced gene 2 | 0.0400624 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0399252 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0393796 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0373414 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0373162 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0371847 |
| HELZ | helicase with zinc finger | 0.0371302 |
| FNBP4 | formin binding protein 4 | 0.0368242 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0364119 |
| SRP54 | signal recognition particle 54kDa | 0.0363755 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0362033 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0361956 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0360926 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0358246 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0357349 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0356582 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0354352 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0350107 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0349718 |
| USP34 | ubiquitin specific peptidase 34 | 0.0348257 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0347576 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0346559 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0345844 |
| YME1L1 | YME1-like 1 ATPase | 0.0345567 |
| JMJD1C | jumonji domain containing 1C | 0.0339903 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0339729 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0339098 |
| SPAG9 | sperm associated antigen 9 | 0.0338055 |
| GOLGA2 | golgin A2 | 0.0337265 |
| WDR26 | WD repeat domain 26 | 0.0336545 |
| NUP58 | nucleoporin 58 | 0.0335841 |
| TXNRD1 | thioredoxin reductase 1 | 0.0335611 |
| GOLGB1 | golgin B1 | 0.0328525 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0328458 |
| OSBP | oxysterol binding protein | 0.0324707 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0323864 |
| SUCO | SUN domain containing ossification factor | 0.0323812 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0323799 |
| HDLBP | high density lipoprotein binding protein | 0.0320113 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0319521 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0317864 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0314936 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0314147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.285783 |
| FAT1 | FAT atypical cadherin 1 | -0.187773 |
| PTMA | prothymosin, alpha | -0.140595 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0852328 |
| TMSB10 | thymosin beta 10 | -0.0805115 |
| POTEF | POTE ankyrin domain family, member F | -0.0777693 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0576235 |
| ENO1 | enolase 1, (alpha) | -0.0526382 |
| TUBA1B | tubulin, alpha 1b | -0.0451501 |
| RPS8 | ribosomal protein S8 | -0.0439252 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0438191 |
| PKM | pyruvate kinase, muscle | -0.0415751 |
| WWOX | WW domain containing oxidoreductase | -0.0410434 |
| CCND1 | cyclin D1 | -0.0403624 |
| ACTG1 | actin gamma 1 | -0.0381191 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0378245 |
| HMGB1 | high mobility group box 1 | -0.0344355 |
| KRT18 | keratin 18, type I | -0.0331525 |
| RPL35A | ribosomal protein L35a | -0.0323065 |
| FHIT | fragile histidine triad | -0.0319162 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0316991 |
| YBX1 | Y box binding protein 1 | -0.0316237 |
| HMGA2 | high mobility group AT-hook 2 | -0.0303558 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0288801 |
| TENM3 | teneurin transmembrane protein 3 | -0.0283961 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0271705 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0268831 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0262312 |
| HELLS | helicase, lymphoid-specific | -0.0259725 |
| EGFR | epidermal growth factor receptor | -0.0254135 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0251425 |
| PFN1 | profilin 1 | -0.0240725 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.0239688 |
| RPS6 | ribosomal protein S6 | -0.0235202 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.023319 |
| LRRC23 | leucine rich repeat containing 23 | -0.0230034 |
| CDCP1 | CUB domain containing protein 1 | -0.0229363 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0228863 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0226957 |
| SERINC5 | serine incorporator 5 | -0.02229 |
| HMGA1 | high mobility group AT-hook 1 | -0.0221561 |
| EGR1 | early growth response 1 | -0.0219297 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0212922 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0211495 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0210544 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0209594 |
| MSI2 | musashi RNA-binding protein 2 | -0.0208364 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0203156 |
| RPS17 | ribosomal protein S17 | -0.0202382 |
| NOP56 | NOP56 ribonucleoprotein | -0.0199554 |
| SEPTIN11 | septin 11 | -0.0198678 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0195631 |
| ITGB4 | integrin, beta 4 | -0.0194807 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -0.0194475 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0194238 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0193634 |
| TUBB | tubulin, beta class I | -0.019333 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0190756 |
| IPO7 | importin 7 | -0.0189768 |
| RPLP1 | ribosomal protein, large, P1 | -0.0189029 |
| DEK | DEK proto-oncogene | -0.0188891 |
| VEGFA | vascular endothelial growth factor A | -0.0185504 |
| PRDX2 | peroxiredoxin 2 | -0.0184393 |
| CADPS | Ca++-dependent secretion activator | -0.0183505 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0181929 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0181578 |
| TNS4 | tensin 4 | -0.0178865 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0178383 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0176229 |
| ZNRF3 | zinc and ring finger 3 | -0.0174341 |
| TMEM123 | transmembrane protein 123 | -0.0173335 |
| RACK1 | receptor for activated C kinase 1 | -0.0172685 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0172646 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0171502 |
| RPS25 | ribosomal protein S25 | -0.01709 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0166667 |
| STMN1 | stathmin 1 | -0.0165469 |
| RPL4 | ribosomal protein L4 | -0.0163282 |
| GPHN | gephyrin | -0.0162389 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0162126 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.016169 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.0160661 |
| MCM4 | minichromosome maintenance complex component 4 | -0.0160268 |
| KRT8 | keratin 8, type II | -0.0159913 |
| S100A6 | S100 calcium binding protein A6 | -0.015699 |
| FUS | FUS RNA binding protein | -0.015695 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0156203 |
| TPM3 | tropomyosin 3 | -0.0154522 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0153751 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0152185 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0150866 |
| EHBP1 | EH domain binding protein 1 | -0.0150513 |
| NFIB | nuclear factor I/B | -0.0150323 |
| RCC1 | regulator of chromosome condensation 1 | -0.0147078 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0145611 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0144987 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0144953 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0144243 |
| VIM | vimentin | -0.0142458 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.0141002 |
