| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.240782 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.173521 |
| MT2A | metallothionein 2A | 0.161988 |
| ASPH | aspartate beta-hydroxylase | 0.132881 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.116769 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.100494 |
| RAD51B | RAD51 paralog B | 0.0859008 |
| PRELID2 | PRELI domain containing 2 | 0.0836331 |
| EGFR | epidermal growth factor receptor | 0.0823965 |
| PAX8 | paired box 8 | 0.0820608 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0819235 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0817537 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0776009 |
| LAMC2 | laminin, gamma 2 | 0.0761625 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0759226 |
| HMGA2 | high mobility group AT-hook 2 | 0.0732341 |
| LDHA | lactate dehydrogenase A | 0.0715581 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0707256 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0706978 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0704155 |
| LAMB3 | laminin, beta 3 | 0.0701298 |
| ITGB8 | integrin, beta 8 | 0.0669182 |
| FLNB | filamin B, beta | 0.0635271 |
| NF1 | neurofibromin 1 | 0.063016 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0618299 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0604203 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0586282 |
| BPTF | bromodomain PHD finger transcription factor | 0.0581518 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0578598 |
| CD44 | CD44 molecule (Indian blood group) | 0.0572717 |
| SETD5 | SET domain containing 5 | 0.0572003 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0559447 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0545496 |
| NDRG1 | N-myc downstream regulated 1 | 0.0525297 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0519955 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0518998 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0513708 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0505508 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0502038 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0501453 |
| ACTG1 | actin gamma 1 | 0.047714 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0476845 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0473109 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.046757 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.045612 |
| WWC1 | WW and C2 domain containing 1 | 0.0452193 |
| SVIL | supervillin | 0.0440036 |
| ANXA2 | annexin A2 | 0.0437999 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0432442 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0424946 |
| ITGA6 | integrin, alpha 6 | 0.0417045 |
| HMGA1 | high mobility group AT-hook 1 | 0.0415422 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.041093 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0408324 |
| CTBP2 | C-terminal binding protein 2 | 0.0401199 |
| PGK1 | phosphoglycerate kinase 1 | 0.0395772 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0390729 |
| SEPTIN9 | septin 9 | 0.0385739 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0384713 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0382649 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0374082 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0368969 |
| ERBIN | erbb2 interacting protein | 0.0368172 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0366852 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0363648 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0362745 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0358371 |
| ANXA3 | annexin A3 | 0.0357111 |
| SBF2 | SET binding factor 2 | 0.0351373 |
| MED13 | mediator complex subunit 13 | 0.0342216 |
| FMNL2 | formin-like 2 | 0.0332668 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0323919 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.032335 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0323297 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0321489 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0319392 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0319119 |
| PTK2 | protein tyrosine kinase 2 | 0.0309878 |
| ZFHX3 | zinc finger homeobox 3 | 0.0309316 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0304634 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0303617 |
| FHIT | fragile histidine triad | 0.0303053 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0302566 |
| ZNF609 | zinc finger protein 609 | 0.0301547 |
| MKI67 | marker of proliferation Ki-67 | 0.0301108 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0299947 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0297726 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0296408 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0295395 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0291479 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.028841 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0288053 |
| AEBP2 | AE binding protein 2 | 0.0287835 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0286417 |
| LAMA4 | laminin, alpha 4 | 0.0286124 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0285684 |
| ACTN1 | actinin, alpha 1 | 0.0285215 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0284861 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0280869 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0280554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | -0.0677134 |
| FTL | ferritin, light polypeptide | -0.0626268 |
| MATR3 | matrin 3 | -0.0603365 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0546636 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0484271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0432077 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0374352 |
| SQSTM1 | sequestosome 1 | -0.037344 |
| GOLGA4 | golgin A4 | -0.0357439 |
| RPS8 | ribosomal protein S8 | -0.0355827 |
| RYBP | RING1 and YY1 binding protein | -0.0326714 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0324446 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0318108 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313514 |
| NCKAP1 | NCK-associated protein 1 | -0.0312562 |
| RPL12 | ribosomal protein L12 | -0.0311163 |
| RPL19 | ribosomal protein L19 | -0.0309736 |
| RPL38 | ribosomal protein L38 | -0.0308625 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0307241 |
| RLF | rearranged L-myc fusion | -0.0297185 |
| TXNRD1 | thioredoxin reductase 1 | -0.0296322 |
| RPS12 | ribosomal protein S12 | -0.0292282 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0290555 |
| SET | SET nuclear proto-oncogene | -0.0288614 |
| HMGB1 | high mobility group box 1 | -0.0281831 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0275553 |
| RPL26 | ribosomal protein L26 | -0.0275384 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0273719 |
| TKT | transketolase | -0.0272053 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0271494 |
| HSPA8 | heat shock 70kDa protein 8 | -0.026728 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0264421 |
| RPL32 | ribosomal protein L32 | -0.0262706 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0260391 |
| NEK7 | NIMA-related kinase 7 | -0.0255202 |
| PCBP2 | poly(rC) binding protein 2 | -0.0252256 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0250041 |
| RPS5 | ribosomal protein S5 | -0.0247353 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0244902 |
| CLINT1 | clathrin interactor 1 | -0.0244001 |
| RPL28 | ribosomal protein L28 | -0.0243996 |
| S100A10 | S100 calcium binding protein A10 | -0.0243321 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0241945 |
| RBM39 | RNA binding motif protein 39 | -0.024126 |
| MAP4 | microtubule-associated protein 4 | -0.0237532 |
| APP | amyloid beta (A4) precursor protein | -0.0236336 |
| RPL4 | ribosomal protein L4 | -0.0232126 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0229793 |
| RPL8 | ribosomal protein L8 | -0.0226904 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0224767 |
| PDS5B | PDS5 cohesin associated factor B | -0.0223183 |
| UBQLN1 | ubiquilin 1 | -0.0218414 |
| RPL36 | ribosomal protein L36 | -0.0217991 |
| AZIN1 | antizyme inhibitor 1 | -0.0214482 |
| IFRD1 | interferon-related developmental regulator 1 | -0.021404 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.021368 |
| RPL6 | ribosomal protein L6 | -0.0213255 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0213105 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0210114 |
| FOSL1 | FOS-like antigen 1 | -0.0210061 |
| ANXA1 | annexin A1 | -0.0209583 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0209531 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0208537 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.020811 |
| ADAR | adenosine deaminase, RNA-specific | -0.0207037 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0206077 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0206048 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0205529 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0205133 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0204592 |
| H1-4 | H1.4 linker histone, cluster member | -0.0203914 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.020258 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0202257 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0201443 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.0201062 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0200391 |
| DSG2 | desmoglein 2 | -0.0199452 |
| KIF5B | kinesin family member 5B | -0.0197992 |
| RPL35 | ribosomal protein L35 | -0.019475 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0194279 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0193904 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.0192595 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0192525 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.019158 |
| USP15 | ubiquitin specific peptidase 15 | -0.019112 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0189955 |
| PTMA | prothymosin, alpha | -0.0189867 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0188996 |
| POTEF | POTE ankyrin domain family, member F | -0.0187389 |
| HMGB2 | high mobility group box 2 | -0.0185419 |
| RPS6 | ribosomal protein S6 | -0.0184997 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0184207 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0182254 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0181557 |
| RPS3 | ribosomal protein S3 | -0.0180085 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0179362 |
| RPLP2 | ribosomal protein, large, P2 | -0.0179289 |
| RBBP7 | retinoblastoma binding protein 7 | -0.0179179 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.017865 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0177482 |
