| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.151964 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.14579 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.126432 |
| FAM13A | family with sequence similarity 13, member A | 0.109316 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0958703 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0857475 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0832524 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0785893 |
| ADM | adrenomedullin | 0.0785616 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0770668 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0755669 |
| SPAG9 | sperm associated antigen 9 | 0.0754452 |
| SETD5 | SET domain containing 5 | 0.0708693 |
| OGA | O-GlcNAcase | 0.0696287 |
| MCL1 | myeloid cell leukemia 1 | 0.0675444 |
| HELZ | helicase with zinc finger | 0.0602596 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0575878 |
| GOLGA4 | golgin A4 | 0.0573767 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0568883 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0556315 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0535376 |
| RASA3 | RAS p21 protein activator 3 | 0.0530138 |
| FLNB | filamin B, beta | 0.0519455 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0511813 |
| MSN | moesin | 0.0510376 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0510239 |
| CD109 | CD109 molecule | 0.0506659 |
| RUNX1 | runt-related transcription factor 1 | 0.0478865 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0475741 |
| COPA | coatomer protein complex, subunit alpha | 0.0469835 |
| DTNA | dystrobrevin, alpha | 0.0469002 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.046712 |
| RBM39 | RNA binding motif protein 39 | 0.0465404 |
| SEC24A | SEC24 family member A | 0.0459647 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0457889 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0456619 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0454075 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0452405 |
| FMNL2 | formin-like 2 | 0.0447184 |
| ATP13A3 | ATPase type 13A3 | 0.0446819 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0436514 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0433513 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0433136 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0429052 |
| ZNF292 | zinc finger protein 292 | 0.0426934 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0426723 |
| NUP58 | nucleoporin 58 | 0.0421088 |
| RNF24 | ring finger protein 24 | 0.0419746 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0404392 |
| NGLY1 | N-glycanase 1 | 0.0403656 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0402202 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0394888 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.03932 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0390751 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0388685 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0388154 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0384789 |
| HPCAL1 | hippocalcin-like 1 | 0.0382198 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0380177 |
| USP3 | ubiquitin specific peptidase 3 | 0.0370447 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0360497 |
| SEPTIN9 | septin 9 | 0.0351213 |
| INSIG2 | insulin induced gene 2 | 0.0348354 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0347434 |
| USP34 | ubiquitin specific peptidase 34 | 0.0340557 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0339202 |
| RLF | rearranged L-myc fusion | 0.0336394 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0331891 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.032818 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0325118 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0323451 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0322186 |
| TNS1 | tensin 1 | 0.032098 |
| MT2A | metallothionein 2A | 0.0319392 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0319025 |
| LOX | lysyl oxidase | 0.0318011 |
| PTK2 | protein tyrosine kinase 2 | 0.0315628 |
| MYO1B | myosin IB | 0.03122 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0310213 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0309864 |
| VMP1 | vacuole membrane protein 1 | 0.0309178 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0308066 |
| ARRDC3 | arrestin domain containing 3 | 0.0307363 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0306246 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0306153 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.030489 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0304729 |
| RNF149 | ring finger protein 149 | 0.0303772 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0303304 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0300689 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0299091 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.029878 |
| G0S2 | G0/G1 switch 2 | 0.0298706 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0297973 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0296117 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0295449 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0293817 |
| CEP192 | centrosomal protein 192kDa | 0.0292121 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291393 |
| SRP54 | signal recognition particle 54kDa | 0.0289891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.15375 |
| ENO1 | enolase 1, (alpha) | -0.128724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127124 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.117982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113564 |
| AHNAK | AHNAK nucleoprotein | -0.104719 |
| CD44 | CD44 molecule (Indian blood group) | -0.0989654 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0908795 |
| TMSB10 | thymosin beta 10 | -0.0895219 |
| HMGA2 | high mobility group AT-hook 2 | -0.0706525 |
| ACTG1 | actin gamma 1 | -0.0574768 |
| NAV1 | neuron navigator 1 | -0.0559169 |
| GLIS3 | GLIS family zinc finger 3 | -0.0542481 |
| CCND1 | cyclin D1 | -0.0528179 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.052649 |
| ASPH | aspartate beta-hydroxylase | -0.0515706 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0514369 |
| IGF2 | insulin-like growth factor 2 | -0.0509499 |
| MAP1B | microtubule-associated protein 1B | -0.0508624 |
| TPM4 | tropomyosin 4 | -0.0484608 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0474461 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0472651 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0471378 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0460422 |
| ANXA2 | annexin A2 | -0.0459736 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0437201 |
| CDCP1 | CUB domain containing protein 1 | -0.0415559 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0405042 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0398177 |
| VCL | vinculin | -0.0392888 |
| FN1 | fibronectin 1 | -0.0372485 |
| TPM1 | tropomyosin 1 (alpha) | -0.0363426 |
| RPL35A | ribosomal protein L35a | -0.0361235 |
| RPL12 | ribosomal protein L12 | -0.0351144 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0347377 |
| CALR | calreticulin | -0.0334163 |
| RPLP1 | ribosomal protein, large, P1 | -0.0332505 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0331434 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0325938 |
| RPS6 | ribosomal protein S6 | -0.031527 |
| RPS8 | ribosomal protein S8 | -0.0314794 |
| PRSS23 | protease, serine, 23 | -0.0313184 |
| TUBB6 | tubulin, beta 6 class V | -0.0310147 |
| EGR1 | early growth response 1 | -0.0298005 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0294695 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0286306 |
| TUBB | tubulin, beta class I | -0.0286149 |
| RPL34 | ribosomal protein L34 | -0.028287 |
| BPTF | bromodomain PHD finger transcription factor | -0.0279833 |
| RAI14 | retinoic acid induced 14 | -0.0275122 |
| CENPF | centromere protein F, 350/400kDa | -0.0270596 |
| DST | dystonin | -0.0270101 |
| S100A10 | S100 calcium binding protein A10 | -0.0269506 |
| POTEF | POTE ankyrin domain family, member F | -0.0259784 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0258158 |
| CANX | calnexin | -0.0252783 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025195 |
| HMGB1 | high mobility group box 1 | -0.0251797 |
| RIN2 | Ras and Rab interactor 2 | -0.0251647 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0249355 |
| UBB | ubiquitin B | -0.024655 |
| RPS24 | ribosomal protein S24 | -0.0246361 |
| CDH13 | cadherin 13 | -0.0245353 |
| COL1A1 | collagen, type I, alpha 1 | -0.024261 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0242386 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0240073 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0233663 |
| EGFR | epidermal growth factor receptor | -0.0232542 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0227297 |
| CDK6 | cyclin-dependent kinase 6 | -0.0225428 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0223171 |
| SYAP1 | synapse associated protein 1 | -0.0223131 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0218635 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.021825 |
| CAVIN1 | caveolae associated protein 1 | -0.0215826 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0215182 |
| PGK1 | phosphoglycerate kinase 1 | -0.0213439 |
| NRP1 | neuropilin 1 | -0.0210794 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0209341 |
| FRMD4A | FERM domain containing 4A | -0.0209112 |
| PXDN | peroxidasin | -0.0208774 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.020676 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0206192 |
| MT1E | metallothionein 1E | -0.0205944 |
| TNNC1 | troponin C type 1 (slow) | -0.0201847 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0201211 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0200724 |
| RPL38 | ribosomal protein L38 | -0.0199542 |
| OSMR | oncostatin M receptor | -0.0199305 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199113 |
| CEP112 | centrosomal protein 112kDa | -0.019855 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0198445 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0197947 |
| GNAS | GNAS complex locus | -0.0197827 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0197503 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0195355 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0195277 |
| MYO9A | myosin IXA | -0.0191892 |
| PALLD | palladin, cytoskeletal associated protein | -0.0190244 |
| PODXL | podocalyxin-like | -0.0188852 |
