| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.155905 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0924095 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.091965 |
| NDRG1 | N-myc downstream regulated 1 | 0.077109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0745285 |
| VEGFA | vascular endothelial growth factor A | 0.0639615 |
| GOLGA4 | golgin A4 | 0.0445671 |
| SQLE | squalene epoxidase | 0.0402109 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0397441 |
| ATP13A3 | ATPase type 13A3 | 0.0396956 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0336458 |
| ARRDC3 | arrestin domain containing 3 | 0.0330333 |
| RASA2 | RAS p21 protein activator 2 | 0.03286 |
| MT2A | metallothionein 2A | 0.0324636 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0302216 |
| SPAG9 | sperm associated antigen 9 | 0.0296004 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0295598 |
| MRTFA | myocardin related transcription factor A | 0.0293923 |
| STC1 | stanniocalcin 1 | 0.0292931 |
| TMEM165 | transmembrane protein 165 | 0.0292496 |
| MSN | moesin | 0.0286935 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0285488 |
| CCNL1 | cyclin L1 | 0.0284192 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270652 |
| MYO9B | myosin IXB | 0.0268549 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0267467 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0266153 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0263528 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0263249 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0261823 |
| VMP1 | vacuole membrane protein 1 | 0.0259463 |
| SETD5 | SET domain containing 5 | 0.0258608 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0257479 |
| CADM1 | cell adhesion molecule 1 | 0.0254837 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0251839 |
| PGM3 | phosphoglucomutase 3 | 0.023558 |
| SRP54 | signal recognition particle 54kDa | 0.0233739 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.023022 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0229775 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0229497 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0226604 |
| COPA | coatomer protein complex, subunit alpha | 0.0217967 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.021776 |
| TFG | TRK-fused gene | 0.0217065 |
| NAV2 | neuron navigator 2 | 0.0215676 |
| NOTCH2 | notch 2 | 0.0210599 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0204572 |
| SMAD3 | SMAD family member 3 | 0.0203653 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0202632 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0201499 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0201128 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0199957 |
| HIP1 | huntingtin interacting protein 1 | 0.0199211 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0198692 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0197234 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0196961 |
| ADM | adrenomedullin | 0.0195307 |
| RAB6A | RAB6A, member RAS oncogene family | 0.019481 |
| MCL1 | myeloid cell leukemia 1 | 0.0193521 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0193359 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0191896 |
| CLINT1 | clathrin interactor 1 | 0.0188826 |
| ZNF292 | zinc finger protein 292 | 0.018713 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0184945 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0182276 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0181613 |
| COG5 | component of oligomeric golgi complex 5 | 0.0181527 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0181392 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0181094 |
| CABIN1 | calcineurin binding protein 1 | 0.0180804 |
| TMF1 | TATA element modulatory factor 1 | 0.0177423 |
| FMNL2 | formin-like 2 | 0.0177298 |
| DIAPH1 | diaphanous-related formin 1 | 0.017715 |
| BRD2 | bromodomain containing 2 | 0.0176485 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0172543 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0170555 |
| SUCO | SUN domain containing ossification factor | 0.0170068 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0169747 |
| GPR107 | G protein-coupled receptor 107 | 0.0168908 |
| UBC | ubiquitin C | 0.0168318 |
| PDE8A | phosphodiesterase 8A | 0.0167525 |
| OPTN | optineurin | 0.0166669 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0165228 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0164755 |
| RPL3 | ribosomal protein L3 | 0.0164689 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0163999 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0161923 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0161441 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0156589 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0155979 |
| FOXJ3 | forkhead box J3 | 0.0155832 |
| FAM107B | family with sequence similarity 107, member B | 0.015515 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.01532 |
| ZNF451 | zinc finger protein 451 | 0.0152504 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0152305 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0149446 |
| ARF4 | ADP-ribosylation factor 4 | 0.0149351 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0149168 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0148472 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0147754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.204761 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.199373 |
| FN1 | fibronectin 1 | -0.161125 |
| COL1A1 | collagen, type I, alpha 1 | -0.150682 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.124916 |
| COL1A2 | collagen, type I, alpha 2 | -0.102406 |
| TPM4 | tropomyosin 4 | -0.101103 |
| CDH13 | cadherin 13 | -0.0930428 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0920315 |
| ASPH | aspartate beta-hydroxylase | -0.0837247 |
| VIM | vimentin | -0.0833798 |
| FBN1 | fibrillin 1 | -0.0824461 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0760418 |
| ENO1 | enolase 1, (alpha) | -0.0755284 |
| VCAN | versican | -0.0734398 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0732335 |
| TMSB10 | thymosin beta 10 | -0.0703589 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0684591 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0660211 |
| AHNAK | AHNAK nucleoprotein | -0.0633277 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0595297 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0595192 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0592465 |
| CANX | calnexin | -0.0572866 |
| IER3 | immediate early response 3 | -0.0560481 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0550088 |
| HMGA2 | high mobility group AT-hook 2 | -0.0505204 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.049452 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0492568 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0478535 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0475603 |
| CALD1 | caldesmon 1 | -0.0466589 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0433311 |
| PRELID2 | PRELI domain containing 2 | -0.042544 |
| MAP1B | microtubule-associated protein 1B | -0.0417031 |
| CNTN5 | contactin 5 | -0.0413179 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0401124 |
| TMSB4X | thymosin beta 4, X-linked | -0.0378235 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0377002 |
| FOXP1 | forkhead box P1 | -0.0359969 |
| DST | dystonin | -0.0354978 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0353161 |
| IL6ST | interleukin 6 signal transducer | -0.0353024 |
| HMCN1 | hemicentin 1 | -0.0351392 |
| COL3A1 | collagen, type III, alpha 1 | -0.0341901 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0332274 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0331519 |
| GLIS3 | GLIS family zinc finger 3 | -0.0330414 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0329118 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0322385 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0319499 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0316623 |
| VCL | vinculin | -0.0303442 |
| EBF1 | early B-cell factor 1 | -0.0296998 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0291855 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0290509 |
| RRBP1 | ribosome binding protein 1 | -0.0287699 |
| TENM3 | teneurin transmembrane protein 3 | -0.0283401 |
| CAVIN1 | caveolae associated protein 1 | -0.0283314 |
| NREP | neuronal regeneration related protein | -0.0280827 |
| NAV3 | neuron navigator 3 | -0.0279948 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279461 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0278085 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0277144 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0276871 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0275698 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0274183 |
| ANXA2 | annexin A2 | -0.0271692 |
| OSMR | oncostatin M receptor | -0.0270923 |
| ATXN1 | ataxin 1 | -0.0270266 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0269989 |
| ACTG1 | actin gamma 1 | -0.0269869 |
| TPM1 | tropomyosin 1 (alpha) | -0.0245546 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0245016 |
| MAP4 | microtubule-associated protein 4 | -0.0242742 |
| NAV1 | neuron navigator 1 | -0.0242679 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0239716 |
| SULF1 | sulfatase 1 | -0.0238101 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0232112 |
| PRSS23 | protease, serine, 23 | -0.0230385 |
| NRP1 | neuropilin 1 | -0.0227133 |
| PXDN | peroxidasin | -0.0225855 |
| COL5A1 | collagen, type V, alpha 1 | -0.0221043 |
| RASAL2 | RAS protein activator like 2 | -0.0220761 |
| NEK10 | NIMA-related kinase 10 | -0.0220248 |
| RIGI | RNA sensor RIG-I | -0.0217592 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0217314 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0217298 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0212433 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0208947 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0206398 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0205292 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0203 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0202218 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0201077 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0198172 |
| EHBP1 | EH domain binding protein 1 | -0.0195295 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0195045 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0193698 |
| HDLBP | high density lipoprotein binding protein | -0.0192693 |
