| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.138321 |
| DSCAM | Down syndrome cell adhesion molecule | 0.112957 |
| LMO7 | LIM domain 7 | 0.111328 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0907701 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0865268 |
| JMJD1C | jumonji domain containing 1C | 0.0785422 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0775767 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0747251 |
| NDRG1 | N-myc downstream regulated 1 | 0.0706367 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0640457 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.064022 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0562158 |
| CD2AP | CD2-associated protein | 0.0550506 |
| ATXN1 | ataxin 1 | 0.0547658 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0516678 |
| GOLGA4 | golgin A4 | 0.0502067 |
| TJP1 | tight junction protein 1 | 0.0493543 |
| BCL2L1 | BCL2-like 1 | 0.0469261 |
| STK24 | serine/threonine kinase 24 | 0.0467358 |
| FNBP4 | formin binding protein 4 | 0.0459301 |
| HKDC1 | hexokinase domain containing 1 | 0.0458493 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0457593 |
| ERBIN | erbb2 interacting protein | 0.0452003 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0443168 |
| DST | dystonin | 0.0440011 |
| TMEM41B | transmembrane protein 41B | 0.0437872 |
| SBF2 | SET binding factor 2 | 0.0433746 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0432286 |
| FRY | furry homolog (Drosophila) | 0.0429722 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.042795 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0422989 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0420415 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.041985 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0417157 |
| RTN4 | reticulon 4 | 0.0416715 |
| NF1 | neurofibromin 1 | 0.0414679 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0405301 |
| ACTN4 | actinin, alpha 4 | 0.0399358 |
| OGA | O-GlcNAcase | 0.0396611 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0391034 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0387181 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0384002 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0380796 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0380702 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0375631 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0373563 |
| SPAG9 | sperm associated antigen 9 | 0.0369423 |
| CLTC | clathrin, heavy chain (Hc) | 0.0366283 |
| PDZD8 | PDZ domain containing 8 | 0.0365394 |
| WASF2 | WAS protein family, member 2 | 0.0365219 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0361877 |
| SMAD3 | SMAD family member 3 | 0.0361115 |
| TMEM45B | transmembrane protein 45B | 0.0360366 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0359875 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0359198 |
| FOXO1 | forkhead box O1 | 0.0358068 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0356537 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0356487 |
| VMP1 | vacuole membrane protein 1 | 0.035519 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0354489 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0354235 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0350319 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0348624 |
| MKI67 | marker of proliferation Ki-67 | 0.0347305 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0341923 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0341483 |
| AFDN | afadin, adherens junction formation factor | 0.0340913 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0338732 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0335138 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0333975 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0331781 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0328796 |
| XPOT | exportin, tRNA | 0.0328098 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0326455 |
| EPCAM | epithelial cell adhesion molecule | 0.0324103 |
| PGK1 | phosphoglycerate kinase 1 | 0.0321327 |
| MED13 | mediator complex subunit 13 | 0.0319415 |
| RAB6A | RAB6A, member RAS oncogene family | 0.031884 |
| GOLGA2 | golgin A2 | 0.0314441 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0313789 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.031208 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0312064 |
| RSF1 | remodeling and spacing factor 1 | 0.0310792 |
| UBC | ubiquitin C | 0.0309298 |
| TJP2 | tight junction protein 2 | 0.0309117 |
| LPIN2 | lipin 2 | 0.0308871 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0307251 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0305951 |
| MYO18A | myosin XVIIIA | 0.0302973 |
| ZNF292 | zinc finger protein 292 | 0.0301621 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0301086 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0299892 |
| ABHD2 | abhydrolase domain containing 2 | 0.0299742 |
| TMC5 | transmembrane channel-like 5 | 0.0299171 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0292735 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0291787 |
| SUCO | SUN domain containing ossification factor | 0.0291035 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0290727 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0289537 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0288835 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0797448 |
| KRT20 | keratin 20, type I | -0.0687688 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0670668 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0628042 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0626374 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.059354 |
| AHNAK | AHNAK nucleoprotein | -0.053283 |
| POTEF | POTE ankyrin domain family, member F | -0.0515673 |
| RPS19 | ribosomal protein S19 | -0.0501681 |
| S100A10 | S100 calcium binding protein A10 | -0.0500218 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0488415 |
| FBXO32 | F-box protein 32 | -0.0450807 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0449156 |
| RPL23 | ribosomal protein L23 | -0.0435162 |
| INTS6 | integrator complex subunit 6 | -0.0419213 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0416699 |
| EMP1 | epithelial membrane protein 1 | -0.0414838 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0398856 |
| HMGB1 | high mobility group box 1 | -0.0388735 |
| LAMA4 | laminin, alpha 4 | -0.0385064 |
| ANXA2 | annexin A2 | -0.038009 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0372886 |
| KRT8 | keratin 8, type II | -0.0365904 |
| RPL8 | ribosomal protein L8 | -0.0359992 |
| TMSB10 | thymosin beta 10 | -0.0351462 |
| EGR1 | early growth response 1 | -0.0346837 |
| PRR5L | proline rich 5 like | -0.034202 |
| RPLP1 | ribosomal protein, large, P1 | -0.0323298 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0321335 |
| DIAPH2 | diaphanous-related formin 2 | -0.0318937 |
| KRT19 | keratin 19, type I | -0.0316537 |
| RPL18 | ribosomal protein L18 | -0.031507 |
| RPS3 | ribosomal protein S3 | -0.0312329 |
| RPL12 | ribosomal protein L12 | -0.0310861 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0305619 |
| RPL28 | ribosomal protein L28 | -0.0300928 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0300585 |
| POF1B | premature ovarian failure, 1B | -0.0293074 |
| KRT18 | keratin 18, type I | -0.0286608 |
| RPS11 | ribosomal protein S11 | -0.0282836 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0281442 |
| TMEM123 | transmembrane protein 123 | -0.0271165 |
| RPL19 | ribosomal protein L19 | -0.0270824 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0263961 |
| PKM | pyruvate kinase, muscle | -0.026046 |
| GNAS | GNAS complex locus | -0.0255154 |
| MMP7 | matrix metallopeptidase 7 | -0.0254727 |
| JUN | jun proto-oncogene | -0.0246758 |
| GSN | gelsolin | -0.0240111 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0239934 |
| RPS8 | ribosomal protein S8 | -0.0229399 |
| CAPN8 | calpain 8 | -0.0229078 |
| EZR | ezrin | -0.0226151 |
| MYADM | myeloid-associated differentiation marker | -0.0221885 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0217249 |
| SGMS2 | sphingomyelin synthase 2 | -0.0215597 |
| FAT1 | FAT atypical cadherin 1 | -0.0214328 |
| RPS5 | ribosomal protein S5 | -0.0206408 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0201377 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0201279 |
| ITGA1 | integrin, alpha 1 | -0.0199012 |
| IFRD1 | interferon-related developmental regulator 1 | -0.019394 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.019214 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0189964 |
| FOSL1 | FOS-like antigen 1 | -0.0189296 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0187813 |
| PERP | PERP, TP53 apoptosis effector | -0.0187123 |
| RPS14 | ribosomal protein S14 | -0.0186 |
| ECT2 | epithelial cell transforming 2 | -0.0185006 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0183813 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0181 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0180306 |
| TAGLN2 | transgelin 2 | -0.017873 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0178198 |
| HOXB3 | homeobox B3 | -0.0176134 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.017288 |
| TLE4 | transducin-like enhancer of split 4 | -0.0172805 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0169003 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0167969 |
| SDC4 | syndecan 4 | -0.0167291 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0165803 |
| ATF3 | activating transcription factor 3 | -0.0165232 |
| EXOC4 | exocyst complex component 4 | -0.0164952 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0164709 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0164707 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0164609 |
| RPS6 | ribosomal protein S6 | -0.0164264 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0163883 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0163792 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0162118 |
| RPS25 | ribosomal protein S25 | -0.0160947 |
| TFRC | transferrin receptor | -0.01608 |
| MECOM | MDS1 and EVI1 complex locus | -0.0160051 |
| KLF10 | Kruppel-like factor 10 | -0.0159339 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0158398 |
| RPS20 | ribosomal protein S20 | -0.0157953 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0157748 |
| RPS4X | ribosomal protein S4, X-linked | -0.015757 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0157486 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0157483 |
