| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.314033 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.298205 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0884962 |
| FN1 | fibronectin 1 | 0.0869158 |
| C3 | complement component 3 | 0.0814388 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0656665 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0647772 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0645361 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0627872 |
| AFDN | afadin, adherens junction formation factor | 0.0627005 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0580752 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0559577 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0546286 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0498525 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0482554 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.046492 |
| VEGFA | vascular endothelial growth factor A | 0.0448646 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0436962 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0434877 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0429913 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0423334 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0406528 |
| KIF5B | kinesin family member 5B | 0.0405376 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0404292 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0400501 |
| VMP1 | vacuole membrane protein 1 | 0.0400333 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0398689 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0391332 |
| TOP1 | topoisomerase (DNA) I | 0.0382101 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0378081 |
| DSPP | dentin sialophosphoprotein | 0.0368221 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0358029 |
| TNS1 | tensin 1 | 0.035119 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.03473 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.034148 |
| CPE | carboxypeptidase E | 0.0332433 |
| PHF3 | PHD finger protein 3 | 0.0323937 |
| LDHA | lactate dehydrogenase A | 0.03237 |
| CDK19 | cyclin-dependent kinase 19 | 0.0321883 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0319444 |
| MCL1 | myeloid cell leukemia 1 | 0.0314516 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0313548 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.031216 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0311941 |
| PRELID2 | PRELI domain containing 2 | 0.0306479 |
| INSIG2 | insulin induced gene 2 | 0.0301379 |
| SMAD3 | SMAD family member 3 | 0.0301075 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0297548 |
| HLF | hepatic leukemia factor | 0.0294668 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0293729 |
| JMJD1C | jumonji domain containing 1C | 0.0288261 |
| NDRG1 | N-myc downstream regulated 1 | 0.0287106 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0286988 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.028529 |
| FOXN3 | forkhead box N3 | 0.0284364 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0282239 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0281539 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.028034 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0277459 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0276184 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0271946 |
| MED13L | mediator complex subunit 13-like | 0.0270653 |
| RPL3 | ribosomal protein L3 | 0.0269656 |
| MYO1B | myosin IB | 0.0268047 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0267803 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0266646 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0262667 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0260337 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0259549 |
| FOXO3 | forkhead box O3 | 0.0257605 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0250521 |
| MALT1 | MALT1 paracaspase | 0.0247807 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0247744 |
| OPTN | optineurin | 0.024724 |
| GOLGA4 | golgin A4 | 0.024393 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0239344 |
| KIF13A | kinesin family member 13A | 0.0237985 |
| FOXO1 | forkhead box O1 | 0.0236234 |
| SETD5 | SET domain containing 5 | 0.0234468 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0233235 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0232906 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0230474 |
| CRLS1 | cardiolipin synthase 1 | 0.0229941 |
| PCGF5 | polycomb group ring finger 5 | 0.0228907 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0228502 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0228461 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0227935 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0227403 |
| ANXA5 | annexin A5 | 0.0225645 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0224455 |
| DIAPH1 | diaphanous-related formin 1 | 0.0222569 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0222502 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0222149 |
| KIF1B | kinesin family member 1B | 0.0220344 |
| ARFGEF3 | ARFGEF family member 3 | 0.0220128 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0219379 |
| HELZ | helicase with zinc finger | 0.0219225 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0218194 |
| GDF15 | growth differentiation factor 15 | 0.0218135 |
| RLF | rearranged L-myc fusion | 0.0218085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EHBP1 | EH domain binding protein 1 | -0.137547 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.126434 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.100456 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0966652 |
| IGF2 | insulin-like growth factor 2 | -0.0735834 |
| GPC6 | glypican 6 | -0.0732168 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0707358 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0660576 |
| FTL | ferritin, light polypeptide | -0.0637264 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0597316 |
| CP | ceruloplasmin (ferroxidase) | -0.0595214 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0561914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0548191 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0538202 |
| GPC3 | glypican 3 | -0.0521132 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0511044 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0502757 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0453275 |
| CNKSR3 | CNKSR family member 3 | -0.0444184 |
| FRMD5 | FERM domain containing 5 | -0.0443381 |
| APOA1 | apolipoprotein A-I | -0.0430864 |
| TMEM123 | transmembrane protein 123 | -0.0430087 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.042887 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0417554 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0416806 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0410748 |
| RPS24 | ribosomal protein S24 | -0.0384872 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0383747 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0345295 |
| TRIM26 | tripartite motif containing 26 | -0.0343348 |
| A2M | alpha-2-macroglobulin | -0.0343028 |
| SYN3 | synapsin III | -0.0341146 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.034074 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.03402 |
| AHSG | alpha-2-HS-glycoprotein | -0.0338156 |
| DST | dystonin | -0.033376 |
| CDK6 | cyclin-dependent kinase 6 | -0.0333353 |
| NHSL1 | NHS-like 1 | -0.0328837 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0322788 |
| APOA2 | apolipoprotein A-II | -0.0319845 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0317836 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0317395 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0312304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0301091 |
| TCF12 | transcription factor 12 | -0.0294467 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0290521 |
| RPL23 | ribosomal protein L23 | -0.028936 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.028746 |
| MATN3 | matrilin 3 | -0.0286881 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0281147 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0280305 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0278208 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0272009 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0267506 |
| PARD3 | par-3 family cell polarity regulator | -0.0258815 |
| TMSB10 | thymosin beta 10 | -0.025872 |
| SELENOP | selenoprotein P | -0.0247727 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0247474 |
| PTCHD4 | patched domain containing 4 | -0.0246432 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.024297 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0236312 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0234073 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.023259 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0231686 |
| FOXP1 | forkhead box P1 | -0.02308 |
| ITGA1 | integrin, alpha 1 | -0.023041 |
| RPL12 | ribosomal protein L12 | -0.0229297 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0229276 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0228378 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.022837 |
| ZFHX3 | zinc finger homeobox 3 | -0.0227416 |
| MCU | mitochondrial calcium uniporter | -0.0225691 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0224199 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.0221046 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0221012 |
| KRT18 | keratin 18, type I | -0.0217955 |
| ARF1 | ADP-ribosylation factor 1 | -0.0216403 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0215568 |
| HDLBP | high density lipoprotein binding protein | -0.0215055 |
| UTRN | utrophin | -0.0214614 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0213714 |
| RRBP1 | ribosome binding protein 1 | -0.0213364 |
| PEG10 | paternally expressed 10 | -0.0206895 |
| MAP4 | microtubule-associated protein 4 | -0.0205516 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0204462 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0199346 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0196935 |
| AK1 | adenylate kinase 1 | -0.0195443 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0195101 |
| SCN1A | sodium channel, voltage gated, type I alpha subunit | -0.0194934 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0192882 |
| APOE | apolipoprotein E | -0.0191678 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.019088 |
| RPS6 | ribosomal protein S6 | -0.0190579 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0190523 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0190218 |
| RPL38 | ribosomal protein L38 | -0.0190026 |
| SEPTIN7 | septin 7 | -0.0188773 |
| MX2 | MX dynamin-like GTPase 2 | -0.0188743 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0188544 |
