| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.0558475 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0458537 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0442712 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0401566 |
| BLCAP | bladder cancer associated protein | 0.0338646 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321955 |
| INTS6 | integrator complex subunit 6 | 0.0319025 |
| MCL1 | myeloid cell leukemia 1 | 0.0291999 |
| KIAA1217 | KIAA1217 | 0.0279827 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0268803 |
| RAD51B | RAD51 paralog B | 0.0256228 |
| SLC35F3 | solute carrier family 35, member F3 | 0.025622 |
| LUZP1 | leucine zipper protein 1 | 0.0253839 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.025319 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0248048 |
| HLA-B | major histocompatibility complex, class I, B | 0.0247723 |
| LAMC2 | laminin, gamma 2 | 0.0242666 |
| FNIP1 | folliculin interacting protein 1 | 0.0237265 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0230293 |
| RAI14 | retinoic acid induced 14 | 0.0215311 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0214383 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0212128 |
| VCL | vinculin | 0.0208493 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0207078 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0206099 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0205496 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0204826 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0195045 |
| OSMR | oncostatin M receptor | 0.0183541 |
| IGF2 | insulin-like growth factor 2 | 0.0181797 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0176201 |
| KIF16B | kinesin family member 16B | 0.0167714 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0165519 |
| PRELID2 | PRELI domain containing 2 | 0.0162076 |
| CLIC4 | chloride intracellular channel 4 | 0.0159447 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0158685 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0155304 |
| LOXL2 | lysyl oxidase-like 2 | 0.0153787 |
| ANTXR2 | anthrax toxin receptor 2 | 0.015254 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0151295 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0150827 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0148764 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0148298 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0143262 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0142636 |
| FOXO1 | forkhead box O1 | 0.0141904 |
| AMOTL1 | angiomotin like 1 | 0.0140472 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0140402 |
| PYGL | phosphorylase, glycogen, liver | 0.013897 |
| RIN2 | Ras and Rab interactor 2 | 0.0137042 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0136834 |
| ATXN1 | ataxin 1 | 0.0132431 |
| HMGA2 | high mobility group AT-hook 2 | 0.0130677 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0128204 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0127794 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0127503 |
| CAPRIN2 | caprin family member 2 | 0.0127299 |
| ITGAV | integrin, alpha V | 0.012681 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.012439 |
| EGFR | epidermal growth factor receptor | 0.0122582 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.012244 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0121103 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0120579 |
| VMP1 | vacuole membrane protein 1 | 0.0120545 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0119889 |
| HDAC9 | histone deacetylase 9 | 0.0119871 |
| PLEC | plectin | 0.0118267 |
| SETX | senataxin | 0.0116309 |
| NAV2 | neuron navigator 2 | 0.0115271 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0114987 |
| RASA3 | RAS p21 protein activator 3 | 0.0114509 |
| FLNB | filamin B, beta | 0.0113434 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.0112591 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.011203 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0111889 |
| SMAD3 | SMAD family member 3 | 0.0111209 |
| YOD1 | YOD1 deubiquitinase | 0.0110285 |
| SYNJ2 | synaptojanin 2 | 0.0109969 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0109781 |
| EFNA5 | ephrin-A5 | 0.0109689 |
| HM13 | histocompatibility (minor) 13 | 0.0108631 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0108379 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0108031 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0108025 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.010673 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.0106292 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0105592 |
| NUMB | numb homolog (Drosophila) | 0.0104975 |
| TNS3 | tensin 3 | 0.010445 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0103649 |
| PMM2 | phosphomannomutase 2 | 0.010039 |
| USP34 | ubiquitin specific peptidase 34 | 0.00990767 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0098978 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.00986197 |
| RUNX1 | runt-related transcription factor 1 | 0.00980946 |
| CDK19 | cyclin-dependent kinase 19 | 0.00978987 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00969256 |
| SH3PXD2A | SH3 and PX domains 2A | 0.00965683 |
| MYO9A | myosin IXA | 0.00963114 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00950153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177886 |
| POTEF | POTE ankyrin domain family, member F | -0.076918 |
| ANXA1 | annexin A1 | -0.0758351 |
| TMSB10 | thymosin beta 10 | -0.062081 |
| ENO1 | enolase 1, (alpha) | -0.0619375 |
| KRT17 | keratin 17, type I | -0.060349 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0589137 |
| S100A10 | S100 calcium binding protein A10 | -0.0558592 |
| CLU | clusterin | -0.0552801 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0541328 |
| RPS6 | ribosomal protein S6 | -0.0531826 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0477852 |
| LMNA | lamin A/C | -0.047763 |
| SULF1 | sulfatase 1 | -0.0439088 |
| DSTN | destrin (actin depolymerizing factor) | -0.0435447 |
| ANXA2 | annexin A2 | -0.0432894 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0427826 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0404749 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0401445 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0400975 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0388585 |
| RPS8 | ribosomal protein S8 | -0.0381215 |
| EZR | ezrin | -0.0380951 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0370355 |
| RPL8 | ribosomal protein L8 | -0.0368462 |
| LDHA | lactate dehydrogenase A | -0.0365158 |
| TAGLN2 | transgelin 2 | -0.0362836 |
| NDRG1 | N-myc downstream regulated 1 | -0.0362169 |
| YBX1 | Y box binding protein 1 | -0.0350397 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.034978 |
| MEF2A | myocyte enhancer factor 2A | -0.0349014 |
| RPS21 | ribosomal protein S21 | -0.0346943 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0344878 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0340893 |
| GNAS | GNAS complex locus | -0.0338178 |
| CD44 | CD44 molecule (Indian blood group) | -0.0336836 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0336032 |
| PKM | pyruvate kinase, muscle | -0.0325175 |
| RPL11 | ribosomal protein L11 | -0.0319846 |
| EMP1 | epithelial membrane protein 1 | -0.0316888 |
| RPS19 | ribosomal protein S19 | -0.0313167 |
| MYOF | myoferlin | -0.0311852 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0305485 |
| S100A2 | S100 calcium binding protein A2 | -0.0303238 |
| FOXP1 | forkhead box P1 | -0.0302338 |
| MT2A | metallothionein 2A | -0.0294869 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0292538 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0291918 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0288546 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0287137 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0281797 |
| PFN1 | profilin 1 | -0.0281455 |
| KRT14 | keratin 14, type I | -0.028079 |
| MORF4L2 | mortality factor 4 like 2 | -0.0275831 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274247 |
| PGK1 | phosphoglycerate kinase 1 | -0.0270958 |
| RBM39 | RNA binding motif protein 39 | -0.0270422 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0266217 |
| RPS3 | ribosomal protein S3 | -0.0263888 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260569 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0260266 |
| RPL35 | ribosomal protein L35 | -0.0258146 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0245861 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0244578 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243443 |
| RPL37 | ribosomal protein L37 | -0.0242806 |
| RPL32 | ribosomal protein L32 | -0.0242727 |
| RPL19 | ribosomal protein L19 | -0.0242222 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0241266 |
| KRT6A | keratin 6A, type II | -0.0239762 |
| FTL | ferritin, light polypeptide | -0.0238228 |
| RPL5 | ribosomal protein L5 | -0.0234895 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0233578 |
| SULF2 | sulfatase 2 | -0.0232908 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.023235 |
| TXNRD1 | thioredoxin reductase 1 | -0.0232169 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0227429 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0227343 |
| RPS2 | ribosomal protein S2 | -0.0226289 |
| S100A9 | S100 calcium binding protein A9 | -0.0225323 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0223901 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0223154 |
| RPS13 | ribosomal protein S13 | -0.0222937 |
| BSG | basigin (Ok blood group) | -0.0222343 |
| RACK1 | receptor for activated C kinase 1 | -0.0221536 |
| RPL23 | ribosomal protein L23 | -0.0221486 |
| RPL28 | ribosomal protein L28 | -0.0221408 |
| MT1X | metallothionein 1X | -0.0220256 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0219121 |
| RPS4X | ribosomal protein S4, X-linked | -0.021808 |
| RPS14 | ribosomal protein S14 | -0.0216308 |
| RPL36 | ribosomal protein L36 | -0.0214249 |
| S100A11 | S100 calcium binding protein A11 | -0.0212788 |
| S100A6 | S100 calcium binding protein A6 | -0.0207837 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0205421 |
| MYO10 | myosin X | -0.0203131 |
| GOLGA4 | golgin A4 | -0.0203102 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0202117 |
| TKT | transketolase | -0.0200979 |
| NEK7 | NIMA-related kinase 7 | -0.0199277 |