| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.145854 |
| GOLGA4 | golgin A4 | 0.0900141 |
| ATP13A3 | ATPase type 13A3 | 0.0780216 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0717369 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0565616 |
| MCL1 | myeloid cell leukemia 1 | 0.0493207 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0490171 |
| FLNB | filamin B, beta | 0.047263 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0471429 |
| B2M | beta-2-microglobulin | 0.0448813 |
| MSN | moesin | 0.0444946 |
| NUP58 | nucleoporin 58 | 0.0439182 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0422712 |
| STK4 | serine/threonine kinase 4 | 0.0410761 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0410334 |
| LOX | lysyl oxidase | 0.0394145 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0393272 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0388865 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0385813 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0385722 |
| UBC | ubiquitin C | 0.0379491 |
| ANXA1 | annexin A1 | 0.0378889 |
| ARF4 | ADP-ribosylation factor 4 | 0.0365704 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0363369 |
| GPR107 | G protein-coupled receptor 107 | 0.034755 |
| TMF1 | TATA element modulatory factor 1 | 0.0341894 |
| GOLGA2 | golgin A2 | 0.0339765 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0338119 |
| MT2A | metallothionein 2A | 0.0337839 |
| MT1X | metallothionein 1X | 0.0336788 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0335307 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0323647 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0318918 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316049 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0314049 |
| NKTR | natural killer cell triggering receptor | 0.0311814 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0309386 |
| NDRG1 | N-myc downstream regulated 1 | 0.03046 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0302722 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0301805 |
| RND3 | Rho family GTPase 3 | 0.0301698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0301267 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0298436 |
| VMP1 | vacuole membrane protein 1 | 0.0297539 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0295826 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0290978 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0290153 |
| SUCO | SUN domain containing ossification factor | 0.0284599 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0275033 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0271753 |
| COPA | coatomer protein complex, subunit alpha | 0.0268733 |
| UBAP1 | ubiquitin associated protein 1 | 0.0268411 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0267994 |
| TMEM165 | transmembrane protein 165 | 0.0264834 |
| DTNA | dystrobrevin, alpha | 0.026442 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.026019 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0260124 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.025727 |
| SRP54 | signal recognition particle 54kDa | 0.0255378 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0254874 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0250526 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0248981 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0245782 |
| SETD5 | SET domain containing 5 | 0.0245057 |
| TPD52 | tumor protein D52 | 0.0240265 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0239314 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0238585 |
| ODF2 | outer dense fiber of sperm tails 2 | 0.0236753 |
| TMEM41B | transmembrane protein 41B | 0.0230441 |
| MKI67 | marker of proliferation Ki-67 | 0.0230196 |
| COG5 | component of oligomeric golgi complex 5 | 0.02292 |
| NOP58 | NOP58 ribonucleoprotein | 0.0227879 |
| GOLT1B | golgi transport 1B | 0.0226682 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0226479 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0226267 |
| ADM | adrenomedullin | 0.0224843 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0224522 |
| TAOK3 | TAO kinase 3 | 0.0223768 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0222586 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0221963 |
| DENND5A | DENN/MADD domain containing 5A | 0.0221751 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0221429 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0220926 |
| CALU | calumenin | 0.021948 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0217826 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0217176 |
| PGK1 | phosphoglycerate kinase 1 | 0.0217138 |
| SMAP1 | small ArfGAP 1 | 0.0216974 |
| MMP12 | matrix metallopeptidase 12 | 0.0214986 |
| GOLGB1 | golgin B1 | 0.0214833 |
| FAM120A | family with sequence similarity 120A | 0.0214421 |
| COG6 | component of oligomeric golgi complex 6 | 0.021279 |
| FOXJ3 | forkhead box J3 | 0.0210952 |
| SEC24A | SEC24 family member A | 0.0209161 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.020877 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0207759 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0206994 |
| NGLY1 | N-glycanase 1 | 0.0205755 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0205745 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0205303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.216785 |
| FTL | ferritin, light polypeptide | -0.117855 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.109567 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0795115 |
| DEK | DEK proto-oncogene | -0.0790165 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0777017 |
| ANXA2 | annexin A2 | -0.0744024 |
| TXNRD1 | thioredoxin reductase 1 | -0.0739311 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0696168 |
| ASPH | aspartate beta-hydroxylase | -0.0647729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.064228 |
| GLIS3 | GLIS family zinc finger 3 | -0.0642235 |
| CCND1 | cyclin D1 | -0.0626052 |
| PLCB4 | phospholipase C, beta 4 | -0.0623316 |
| POTEF | POTE ankyrin domain family, member F | -0.061491 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0577972 |
| HLA-B | major histocompatibility complex, class I, B | -0.0575728 |
| TENM3 | teneurin transmembrane protein 3 | -0.05704 |
| TPM1 | tropomyosin 1 (alpha) | -0.0567556 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0566437 |
| AHNAK | AHNAK nucleoprotein | -0.0556062 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0550201 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0545897 |
| HMGB1 | high mobility group box 1 | -0.0531659 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0526862 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0525294 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0520216 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0517853 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0515216 |
| KRT18 | keratin 18, type I | -0.0498212 |
| SQSTM1 | sequestosome 1 | -0.0490895 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0486543 |
| KRT7 | keratin 7, type II | -0.0485471 |
| CAVIN1 | caveolae associated protein 1 | -0.0483516 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0475077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0467133 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0463317 |
| ZNF804A | zinc finger protein 804A | -0.0458449 |
| HLA-C | major histocompatibility complex, class I, C | -0.0458005 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0455941 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0447964 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0415143 |
| PLSCR1 | phospholipid scramblase 1 | -0.0413945 |
| MAP1B | microtubule-associated protein 1B | -0.0412781 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0411834 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0411793 |
| ENO1 | enolase 1, (alpha) | -0.0411541 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0405858 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0404753 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0400158 |
| DIAPH3 | diaphanous-related formin 3 | -0.039111 |
| ACTG1 | actin gamma 1 | -0.0390894 |
| RNF213 | ring finger protein 213 | -0.0388881 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.038681 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0375527 |
| RPL35A | ribosomal protein L35a | -0.0375165 |
| PODXL | podocalyxin-like | -0.0374297 |
| FLNA | filamin A, alpha | -0.0374274 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365307 |
| SULF1 | sulfatase 1 | -0.0360203 |
| TMSB10 | thymosin beta 10 | -0.0360114 |
| CD44 | CD44 molecule (Indian blood group) | -0.0353209 |
| RPS6 | ribosomal protein S6 | -0.0352235 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0352119 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0351864 |
| MYLK | myosin light chain kinase | -0.0350213 |
| FHIT | fragile histidine triad | -0.0349354 |
| FOXP1 | forkhead box P1 | -0.0348873 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0337401 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0334891 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0333923 |
| THBS1 | thrombospondin 1 | -0.0332867 |
| RIGI | RNA sensor RIG-I | -0.033262 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0332358 |
| PKM | pyruvate kinase, muscle | -0.0326094 |
| LIMA1 | LIM domain and actin binding 1 | -0.0323495 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.03208 |
| TUBB | tubulin, beta class I | -0.0320053 |
| JUN | jun proto-oncogene | -0.0318988 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0315457 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0313786 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0313597 |
| KRT8 | keratin 8, type II | -0.0308619 |
| ZNF432 | zinc finger protein 432 | -0.0306873 |
| NAV2 | neuron navigator 2 | -0.0306213 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0305319 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0302384 |
| MORF4L2 | mortality factor 4 like 2 | -0.0301518 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.029974 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0289343 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0286378 |
| GNAS | GNAS complex locus | -0.0284667 |
| RPL12 | ribosomal protein L12 | -0.0283704 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0283452 |
| RPL5 | ribosomal protein L5 | -0.02827 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0281016 |
| ATXN1 | ataxin 1 | -0.0280783 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0279198 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0277327 |
| RPS8 | ribosomal protein S8 | -0.0276873 |
