| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.258548 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.175822 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.167745 |
| EFNA5 | ephrin-A5 | 0.150836 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.13658 |
| EXT1 | exostosin glycosyltransferase 1 | 0.106816 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.101413 |
| NUP58 | nucleoporin 58 | 0.0917304 |
| RUNX1 | runt-related transcription factor 1 | 0.091709 |
| MMP12 | matrix metallopeptidase 12 | 0.0910982 |
| MSN | moesin | 0.0828734 |
| DST | dystonin | 0.0805298 |
| JMJD1C | jumonji domain containing 1C | 0.0785423 |
| CALD1 | caldesmon 1 | 0.0743314 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0731188 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0708172 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0701849 |
| HDAC9 | histone deacetylase 9 | 0.0699179 |
| MCL1 | myeloid cell leukemia 1 | 0.0692285 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0685631 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0685462 |
| MYO10 | myosin X | 0.0678914 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0663601 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0638166 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0633214 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0629884 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.060779 |
| USP34 | ubiquitin specific peptidase 34 | 0.0605688 |
| MED13L | mediator complex subunit 13-like | 0.0585034 |
| TLE4 | transducin-like enhancer of split 4 | 0.0582384 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0573073 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0571561 |
| FRMD6 | FERM domain containing 6 | 0.0569279 |
| SPAG9 | sperm associated antigen 9 | 0.056687 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0559817 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0547368 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.05444 |
| ATP13A3 | ATPase type 13A3 | 0.0536652 |
| VIM | vimentin | 0.0534143 |
| CD109 | CD109 molecule | 0.0528657 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0519809 |
| NF1 | neurofibromin 1 | 0.0513571 |
| WDR43 | WD repeat domain 43 | 0.0498155 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0495016 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0492969 |
| SETD5 | SET domain containing 5 | 0.0489615 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0467974 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0463828 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.046377 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0462039 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0459425 |
| CD163L1 | CD163 molecule-like 1 | 0.0456506 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.045303 |
| BRD2 | bromodomain containing 2 | 0.0447289 |
| PRKCE | protein kinase C, epsilon | 0.0444799 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0439117 |
| LDHA | lactate dehydrogenase A | 0.0438192 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0435809 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0431982 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0430648 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.04301 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0427857 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.042428 |
| ERBIN | erbb2 interacting protein | 0.0420088 |
| GPC6 | glypican 6 | 0.0418167 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0415447 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0414519 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0412738 |
| ASPH | aspartate beta-hydroxylase | 0.0408967 |
| YEATS2 | YEATS domain containing 2 | 0.0407186 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0401202 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0399617 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0398835 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0396372 |
| PTK2 | protein tyrosine kinase 2 | 0.0396171 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.039479 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0387843 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0385062 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0384105 |
| SMAP1 | small ArfGAP 1 | 0.0383191 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0379004 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0378633 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0377598 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0371853 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.037096 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0366589 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0364467 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.035796 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0357834 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.035778 |
| NBAS | neuroblastoma amplified sequence | 0.0356727 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0352896 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.035279 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0349384 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0348898 |
| ANO6 | anoctamin 6 | 0.034782 |
| RBM39 | RNA binding motif protein 39 | 0.0347372 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0346936 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0343821 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0342476 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0921515 |
| FTL | ferritin, light polypeptide | -0.0810784 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.076213 |
| TMSB10 | thymosin beta 10 | -0.0652611 |
| PTMA | prothymosin, alpha | -0.0623903 |
| AHNAK | AHNAK nucleoprotein | -0.0582726 |
| RPL35A | ribosomal protein L35a | -0.0572426 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0502593 |
| RPS24 | ribosomal protein S24 | -0.0449107 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0359189 |
| HMGB1 | high mobility group box 1 | -0.0345618 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343055 |
| IER3 | immediate early response 3 | -0.0322209 |
| RPL12 | ribosomal protein L12 | -0.0322118 |
| RPS8 | ribosomal protein S8 | -0.0300016 |
| RPL38 | ribosomal protein L38 | -0.0293908 |
| RPL34 | ribosomal protein L34 | -0.02869 |
| RPL4 | ribosomal protein L4 | -0.0283896 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0271748 |
| CAVIN1 | caveolae associated protein 1 | -0.0269464 |
| RPL23 | ribosomal protein L23 | -0.0264131 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0243496 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0230418 |
| RPL6 | ribosomal protein L6 | -0.0229233 |
| DEK | DEK proto-oncogene | -0.0228775 |
| CCND1 | cyclin D1 | -0.0218846 |
| TPM4 | tropomyosin 4 | -0.0214367 |
| RPL8 | ribosomal protein L8 | -0.0210575 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0203673 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0201508 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0193608 |
| GNAS | GNAS complex locus | -0.0192603 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0189754 |
| RPS19 | ribosomal protein S19 | -0.0189335 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0188478 |
| CDH13 | cadherin 13 | -0.0188164 |
| HMGA1 | high mobility group AT-hook 1 | -0.0185741 |
| RPLP0 | ribosomal protein, large, P0 | -0.0185226 |
| TUBB | tubulin, beta class I | -0.0173611 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.017347 |
| TMEM123 | transmembrane protein 123 | -0.0173334 |
| RIGI | RNA sensor RIG-I | -0.0170619 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0168564 |
| RPL26 | ribosomal protein L26 | -0.0163527 |
| RPS16 | ribosomal protein S16 | -0.0162353 |
| NRP2 | neuropilin 2 | -0.0160356 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0158821 |
| RPLP2 | ribosomal protein, large, P2 | -0.0155853 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0150884 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0149534 |
| RPL32 | ribosomal protein L32 | -0.0147617 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0146283 |
| NTNG2 | netrin G2 | -0.0144382 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0143957 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0142495 |
| POTEF | POTE ankyrin domain family, member F | -0.0140879 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0140664 |
| UBB | ubiquitin B | -0.0140448 |
| YBX1 | Y box binding protein 1 | -0.0138064 |
| CENPF | centromere protein F, 350/400kDa | -0.013663 |
| TKT | transketolase | -0.0136537 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0135269 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0134497 |
| PCDH11X | protocadherin 11 X-linked | -0.013409 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0133079 |
| HDLBP | high density lipoprotein binding protein | -0.0127564 |
| SQSTM1 | sequestosome 1 | -0.0127442 |
| CANX | calnexin | -0.01253 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0125028 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0122582 |
| TUBB6 | tubulin, beta 6 class V | -0.0121951 |
| RRBP1 | ribosome binding protein 1 | -0.0121589 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0120854 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0120798 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0120649 |
| RPL27 | ribosomal protein L27 | -0.0119123 |
| H1-0 | H1.0 linker histone | -0.0118809 |
| S100A6 | S100 calcium binding protein A6 | -0.0118779 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0118737 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.01187 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0118083 |
| RPS27A | ribosomal protein S27a | -0.0118049 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.0117569 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0117334 |
| HLA-E | major histocompatibility complex, class I, E | -0.0116822 |
| RPS11 | ribosomal protein S11 | -0.0116321 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0116275 |
| ITGA6 | integrin, alpha 6 | -0.0115664 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0115489 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0115357 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0114475 |
| HLA-B | major histocompatibility complex, class I, B | -0.0114337 |
| HMGB2 | high mobility group box 2 | -0.0114231 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0114006 |
| TEX14 | testis expressed 14 | -0.0113428 |
| RPS4X | ribosomal protein S4, X-linked | -0.0112352 |
| VCL | vinculin | -0.0111335 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0110746 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0110744 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0110697 |
