| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.147043 |
| FLNB | filamin B, beta | 0.142072 |
| FAT1 | FAT atypical cadherin 1 | 0.128181 |
| AREG | amphiregulin | 0.116415 |
| ITGA6 | integrin, alpha 6 | 0.114362 |
| PTMA | prothymosin, alpha | 0.101046 |
| EPCAM | epithelial cell adhesion molecule | 0.0964781 |
| ANXA2 | annexin A2 | 0.093068 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0894505 |
| LMO7 | LIM domain 7 | 0.0879558 |
| NPSR1 | neuropeptide S receptor 1 | 0.0857703 |
| PGK1 | phosphoglycerate kinase 1 | 0.0785667 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0784433 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0776765 |
| LDHA | lactate dehydrogenase A | 0.0773797 |
| ACTN4 | actinin, alpha 4 | 0.0749047 |
| ONECUT3 | one cut homeobox 3 | 0.0747546 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0733463 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.073086 |
| MYO1E | myosin IE | 0.0729418 |
| H1-0 | H1.0 linker histone | 0.0716109 |
| ASPH | aspartate beta-hydroxylase | 0.0714619 |
| KRT8 | keratin 8, type II | 0.0701891 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0698952 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0691627 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0683024 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0681677 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0657664 |
| NDRG1 | N-myc downstream regulated 1 | 0.0640466 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0625372 |
| TXNIP | thioredoxin interacting protein | 0.0610432 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0600902 |
| SETD5 | SET domain containing 5 | 0.0599166 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0592781 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.059146 |
| EREG | epiregulin | 0.058199 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0577466 |
| MED13L | mediator complex subunit 13-like | 0.0577187 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0576726 |
| OGA | O-GlcNAcase | 0.056244 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0550647 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0544803 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0534722 |
| FAM13A | family with sequence similarity 13, member A | 0.0533053 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0532118 |
| CCNY | cyclin Y | 0.0530802 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0521515 |
| KIF5B | kinesin family member 5B | 0.0520611 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0520408 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0520237 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0506711 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0504414 |
| RNF43 | ring finger protein 43 | 0.0503673 |
| TMSB10 | thymosin beta 10 | 0.0495285 |
| ABHD2 | abhydrolase domain containing 2 | 0.0494325 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0478988 |
| CALB1 | calbindin 1, 28kDa | 0.047802 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0477025 |
| KRT18 | keratin 18, type I | 0.0465246 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.046414 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0461312 |
| MCL1 | myeloid cell leukemia 1 | 0.0453671 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.045274 |
| ITGB4 | integrin, beta 4 | 0.0450738 |
| MED13 | mediator complex subunit 13 | 0.0448737 |
| RNF145 | ring finger protein 145 | 0.0448507 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.044239 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0436534 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.043617 |
| FOXO1 | forkhead box O1 | 0.0433329 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0433233 |
| MSI2 | musashi RNA-binding protein 2 | 0.0429222 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0428932 |
| PIGR | polymeric immunoglobulin receptor | 0.0427868 |
| LAMB3 | laminin, beta 3 | 0.0418488 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0417674 |
| RAB6A | RAB6A, member RAS oncogene family | 0.041002 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0404726 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0400983 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0396952 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0396634 |
| LAMA4 | laminin, alpha 4 | 0.0392491 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0391782 |
| GDF15 | growth differentiation factor 15 | 0.03916 |
| VMP1 | vacuole membrane protein 1 | 0.03897 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0389351 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0386429 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0382007 |
| UBC | ubiquitin C | 0.0379731 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0378089 |
| FERMT1 | fermitin family member 1 | 0.0377309 |
| PRSS3 | protease, serine, 3 | 0.037048 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0369046 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0366336 |
| NF1 | neurofibromin 1 | 0.0366238 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.036569 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0365422 |
| GOLGA4 | golgin A4 | 0.036287 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0362775 |
| RREB1 | ras responsive element binding protein 1 | 0.03612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | -0.130845 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123153 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.117305 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100686 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0618005 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0488801 |
| RPS8 | ribosomal protein S8 | -0.047646 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0464207 |
| RPL12 | ribosomal protein L12 | -0.0434531 |
| VEGFA | vascular endothelial growth factor A | -0.0422897 |
| RPS3 | ribosomal protein S3 | -0.0390621 |
| RPS6 | ribosomal protein S6 | -0.0359287 |
| RPS12 | ribosomal protein S12 | -0.0358954 |
| DSPP | dentin sialophosphoprotein | -0.0348208 |
| POTEF | POTE ankyrin domain family, member F | -0.0343645 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330615 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0328983 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0323217 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0315365 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0315075 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289246 |
| RPL26 | ribosomal protein L26 | -0.0283969 |
| CENPF | centromere protein F, 350/400kDa | -0.0281734 |
| RPL4 | ribosomal protein L4 | -0.0272175 |
| YBX1 | Y box binding protein 1 | -0.0266019 |
| RPL38 | ribosomal protein L38 | -0.0249585 |
| RPS20 | ribosomal protein S20 | -0.0244308 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0234408 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0233273 |
| RPL21 | ribosomal protein L21 | -0.0231403 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0229856 |
| FHIT | fragile histidine triad | -0.0229268 |
| RPL27 | ribosomal protein L27 | -0.0227817 |
| H1-4 | H1.4 linker histone, cluster member | -0.0222999 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0222402 |
| DSG2 | desmoglein 2 | -0.0216351 |
| RPL28 | ribosomal protein L28 | -0.0210452 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0210186 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0210142 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0206327 |
| WBP11 | WW domain binding protein 11 | -0.0201315 |
| RPS17 | ribosomal protein S17 | -0.019945 |
| RPS18 | ribosomal protein S18 | -0.0199096 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0197898 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0197158 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0189478 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0187715 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0184213 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0183831 |
| RYBP | RING1 and YY1 binding protein | -0.0181533 |
| AHR | aryl hydrocarbon receptor | -0.0181433 |
| RPL8 | ribosomal protein L8 | -0.0177782 |
| RPL36 | ribosomal protein L36 | -0.0176698 |
| FBXO32 | F-box protein 32 | -0.0176633 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0176212 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0173383 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0172437 |
| MT2A | metallothionein 2A | -0.0171581 |
| EPHB2 | EPH receptor B2 | -0.0169919 |
| GOLGB1 | golgin B1 | -0.0169817 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0168419 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0167344 |
| CDK1 | cyclin-dependent kinase 1 | -0.0164056 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0163945 |
| RPS27 | ribosomal protein S27 | -0.0162649 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0161762 |
| ATF4 | activating transcription factor 4 | -0.0161722 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.0161377 |
| RPL6 | ribosomal protein L6 | -0.0160141 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0159051 |
| CCND1 | cyclin D1 | -0.0158301 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0156847 |
| NEK7 | NIMA-related kinase 7 | -0.0156422 |
| H2AZ1 | H2A.Z variant histone 1 | -0.0153115 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0150547 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0150188 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0150071 |
| HOOK1 | hook microtubule-tethering protein 1 | -0.0149992 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0149393 |
| RPL37A | ribosomal protein L37a | -0.014854 |
| NPTN | neuroplastin | -0.0148016 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0147692 |
| TPR | translocated promoter region, nuclear basket protein | -0.0147657 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0146368 |
| TUBA1B | tubulin, alpha 1b | -0.0146027 |
| DIPK2A | divergent protein kinase domain 2A | -0.0145747 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0145661 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0145301 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0145265 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0143162 |
| SGMS2 | sphingomyelin synthase 2 | -0.0142747 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0142326 |
| KITLG | KIT ligand | -0.0141028 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0138185 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0138111 |
| PDZD8 | PDZ domain containing 8 | -0.0138086 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0137457 |
| MTERF1 | mitochondrial transcription termination factor 1 | -0.013741 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.013561 |
| RTRAF | RNA transcription, translation and transport factor | -0.0135131 |
