| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.15923 |
| CALB1 | calbindin 1, 28kDa | 0.110145 |
| FLNB | filamin B, beta | 0.0951205 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0736993 |
| FAT1 | FAT atypical cadherin 1 | 0.0693119 |
| DSPP | dentin sialophosphoprotein | 0.0689054 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0680862 |
| ITGA6 | integrin, alpha 6 | 0.0678608 |
| MSI2 | musashi RNA-binding protein 2 | 0.0661778 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0645119 |
| LMO7 | LIM domain 7 | 0.0636357 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0619528 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0604655 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0596651 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0592127 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0589996 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0562521 |
| EZR | ezrin | 0.0550688 |
| TJP1 | tight junction protein 1 | 0.0509389 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0505193 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0487913 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0486302 |
| LDHA | lactate dehydrogenase A | 0.0473701 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0470821 |
| GOLGA4 | golgin A4 | 0.0443945 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0430227 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0420669 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0412532 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0410174 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.040815 |
| KRT18 | keratin 18, type I | 0.0406394 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0402563 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0402362 |
| SLTM | SAFB-like, transcription modulator | 0.0401345 |
| OXSR1 | oxidative stress responsive 1 | 0.0390695 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0388333 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0361244 |
| MYO5B | myosin VB | 0.0360964 |
| RPL3 | ribosomal protein L3 | 0.0352846 |
| ANXA11 | annexin A11 | 0.0350783 |
| MED13L | mediator complex subunit 13-like | 0.034973 |
| FBXO11 | F-box protein 11 | 0.0349185 |
| LAMA4 | laminin, alpha 4 | 0.0345514 |
| PCBP2 | poly(rC) binding protein 2 | 0.0344422 |
| SETD5 | SET domain containing 5 | 0.0342555 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0332598 |
| POTEF | POTE ankyrin domain family, member F | 0.0329787 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0323428 |
| DSG3 | desmoglein 3 | 0.0322462 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0318098 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0317564 |
| RCOR1 | REST corepressor 1 | 0.0315797 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031501 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0313118 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0311373 |
| DIAPH1 | diaphanous-related formin 1 | 0.0310745 |
| TRIM2 | tripartite motif containing 2 | 0.0310243 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0307709 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0304853 |
| KRT8 | keratin 8, type II | 0.0303384 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0302234 |
| CTBP2 | C-terminal binding protein 2 | 0.0299914 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0296804 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0294533 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.029414 |
| S100A6 | S100 calcium binding protein A6 | 0.0293284 |
| ETNK1 | ethanolamine kinase 1 | 0.0291698 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0291579 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.028989 |
| SLK | STE20-like kinase | 0.0289497 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0289232 |
| COPA | coatomer protein complex, subunit alpha | 0.0287829 |
| MCU | mitochondrial calcium uniporter | 0.0284589 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0281437 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0278699 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.027258 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272415 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0272138 |
| SLMAP | sarcolemma associated protein | 0.0271704 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0270945 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0269502 |
| CLDN4 | claudin 4 | 0.0269097 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0268883 |
| SH3D19 | SH3 domain containing 19 | 0.0266407 |
| CAV2 | caveolin 2 | 0.0261309 |
| VMP1 | vacuole membrane protein 1 | 0.0260601 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0256899 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0256147 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0255864 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0255086 |
| CLIC5 | chloride intracellular channel 5 | 0.025378 |
| PERP | PERP, TP53 apoptosis effector | 0.0252637 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0252447 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0251682 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0250679 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0249184 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0248832 |
| ACTN4 | actinin, alpha 4 | 0.024826 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0247591 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0247271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | -0.239391 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.104862 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.084167 |
| RPS19 | ribosomal protein S19 | -0.0713924 |
| RPL35A | ribosomal protein L35a | -0.0692267 |
| RPL26 | ribosomal protein L26 | -0.0641939 |
| RPLP2 | ribosomal protein, large, P2 | -0.0629563 |
| RPL12 | ribosomal protein L12 | -0.061436 |
| RPS8 | ribosomal protein S8 | -0.0596028 |
| RPL34 | ribosomal protein L34 | -0.0594577 |
| TMSB10 | thymosin beta 10 | -0.0527336 |
| RPS6 | ribosomal protein S6 | -0.0507579 |
| RPS29 | ribosomal protein S29 | -0.0497045 |
| RPS23 | ribosomal protein S23 | -0.0485593 |
| RPL4 | ribosomal protein L4 | -0.0472777 |
| RPL13A | ribosomal protein L13a | -0.0464864 |
| TXNRD1 | thioredoxin reductase 1 | -0.0446033 |
| RPLP0 | ribosomal protein, large, P0 | -0.0443227 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0439249 |
| RPS12 | ribosomal protein S12 | -0.0404695 |
| RPL5 | ribosomal protein L5 | -0.040376 |
| RPL36 | ribosomal protein L36 | -0.0403678 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.040048 |
| RPL38 | ribosomal protein L38 | -0.0390501 |
| RPS20 | ribosomal protein S20 | -0.038614 |
| RPL32 | ribosomal protein L32 | -0.0363422 |
| RPS16 | ribosomal protein S16 | -0.0363202 |
| RPS24 | ribosomal protein S24 | -0.0358581 |
| RPS27A | ribosomal protein S27a | -0.0351685 |
| IER3 | immediate early response 3 | -0.0350209 |
| RPL19 | ribosomal protein L19 | -0.0322935 |
| RPS3 | ribosomal protein S3 | -0.0316952 |
| RPS25 | ribosomal protein S25 | -0.0307755 |
| RPL23 | ribosomal protein L23 | -0.0294983 |
| RPL28 | ribosomal protein L28 | -0.0290816 |
| MT2A | metallothionein 2A | -0.028001 |
| RPS27 | ribosomal protein S27 | -0.027797 |
| RPL31 | ribosomal protein L31 | -0.027542 |
| RPL37A | ribosomal protein L37a | -0.0273245 |
| RPL30 | ribosomal protein L30 | -0.0268525 |
| RPL35 | ribosomal protein L35 | -0.0267825 |
| RPS13 | ribosomal protein S13 | -0.0257543 |
| RPS5 | ribosomal protein S5 | -0.0253217 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0252937 |
| RPS4X | ribosomal protein S4, X-linked | -0.0249268 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0232482 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0226112 |
| EGR1 | early growth response 1 | -0.0223114 |
| RPS21 | ribosomal protein S21 | -0.0218753 |
| RPL37 | ribosomal protein L37 | -0.0212469 |
| RPL27A | ribosomal protein L27a | -0.0205363 |
| FTL | ferritin, light polypeptide | -0.0204677 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0203072 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0202537 |
| KLF6 | Kruppel-like factor 6 | -0.0196793 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0191443 |
| RPL8 | ribosomal protein L8 | -0.0186407 |
| RIGI | RNA sensor RIG-I | -0.0180496 |
| PTMA | prothymosin, alpha | -0.018049 |
| RPL11 | ribosomal protein L11 | -0.0176232 |
| RPL9 | ribosomal protein L9 | -0.0172002 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0171539 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0170328 |
| RPS11 | ribosomal protein S11 | -0.0169103 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0168386 |
| HLA-C | major histocompatibility complex, class I, C | -0.0167292 |
| ATF4 | activating transcription factor 4 | -0.0164961 |
| RPS14 | ribosomal protein S14 | -0.0162522 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0161562 |
| SEC61G | Sec61 gamma subunit | -0.0161225 |
| RPS15 | ribosomal protein S15 | -0.0159235 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0159011 |
| TRIM56 | tripartite motif containing 56 | -0.015624 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0154947 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0154017 |
| RPL18 | ribosomal protein L18 | -0.0153596 |
| DEK | DEK proto-oncogene | -0.0152072 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0151575 |
| AGR2 | anterior gradient 2 | -0.0150095 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0148826 |
| HMGB1 | high mobility group box 1 | -0.0148623 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0146246 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0146025 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0140513 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0139642 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0138395 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0138178 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0136917 |
| XAF1 | XIAP associated factor 1 | -0.0136718 |
| UBB | ubiquitin B | -0.0135887 |
| ATXN1 | ataxin 1 | -0.0133174 |
| GDF15 | growth differentiation factor 15 | -0.0133129 |
| SEPTIN7 | septin 7 | -0.0132961 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0132703 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.013255 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0132498 |
| MATR3 | matrin 3 | -0.0131812 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0131308 |
| NPR2 | natriuretic peptide receptor 2 | -0.0130865 |
| RPL6 | ribosomal protein L6 | -0.0130713 |
