| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.10412 |
| RAI1 | retinoic acid induced 1 | 0.0902222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0620505 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0511987 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0485955 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0485797 |
| CAPRIN2 | caprin family member 2 | 0.0473284 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0431925 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0429366 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0403034 |
| FNIP1 | folliculin interacting protein 1 | 0.0400929 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0381099 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0378775 |
| YEATS2 | YEATS domain containing 2 | 0.0377978 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0373756 |
| SPAG9 | sperm associated antigen 9 | 0.037241 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0368631 |
| PTMA | prothymosin, alpha | 0.0367487 |
| JMJD1C | jumonji domain containing 1C | 0.0364856 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0361111 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0354606 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0349561 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0340486 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0333051 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0325739 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0324055 |
| OGA | O-GlcNAcase | 0.0322352 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0316407 |
| SBF2 | SET binding factor 2 | 0.0316281 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0309851 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0309245 |
| CDK19 | cyclin-dependent kinase 19 | 0.0305578 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0297246 |
| USP34 | ubiquitin specific peptidase 34 | 0.0295281 |
| MYOF | myoferlin | 0.0294668 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.029275 |
| GOLGA4 | golgin A4 | 0.0289497 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0289074 |
| TMEM41B | transmembrane protein 41B | 0.0286115 |
| MSN | moesin | 0.0284691 |
| DST | dystonin | 0.0280988 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0278313 |
| EZR | ezrin | 0.0277826 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0277071 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0275857 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0269807 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.026647 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0266349 |
| TMSB4X | thymosin beta 4, X-linked | 0.0260966 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0260909 |
| VMP1 | vacuole membrane protein 1 | 0.0260298 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0257992 |
| LOXL2 | lysyl oxidase-like 2 | 0.0256434 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.025529 |
| CANX | calnexin | 0.025435 |
| DOCK11 | dedicator of cytokinesis 11 | 0.025335 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0252838 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0252455 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0251183 |
| TXNRD1 | thioredoxin reductase 1 | 0.0250838 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0248952 |
| MCL1 | myeloid cell leukemia 1 | 0.0246986 |
| NAV2 | neuron navigator 2 | 0.0245713 |
| TXNIP | thioredoxin interacting protein | 0.0245015 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0244756 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0244572 |
| SETD5 | SET domain containing 5 | 0.0244446 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0242314 |
| XPO1 | exportin 1 | 0.0239156 |
| FLNB | filamin B, beta | 0.0239021 |
| CLTC | clathrin, heavy chain (Hc) | 0.0234784 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0233763 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0232624 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0231883 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0231039 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0230512 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0229005 |
| RTN4 | reticulon 4 | 0.0223405 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0222803 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0221456 |
| FMNL2 | formin-like 2 | 0.022085 |
| HDAC9 | histone deacetylase 9 | 0.0219643 |
| PYGL | phosphorylase, glycogen, liver | 0.0219492 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0218381 |
| APP | amyloid beta (A4) precursor protein | 0.0214011 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0213582 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0212942 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0211474 |
| FNBP4 | formin binding protein 4 | 0.021118 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0207749 |
| CD109 | CD109 molecule | 0.0207747 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0206504 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.020539 |
| WDR26 | WD repeat domain 26 | 0.0200949 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0200714 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0198552 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0193475 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.01923 |
| UPP1 | uridine phosphorylase 1 | 0.019211 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0191313 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118003 |
| TMSB10 | thymosin beta 10 | -0.0889276 |
| MT2A | metallothionein 2A | -0.0689354 |
| TP63 | tumor protein p63 | -0.0589285 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0544021 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0524848 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0433353 |
| FTL | ferritin, light polypeptide | -0.034732 |
| RIGI | RNA sensor RIG-I | -0.0318093 |
| RPL12 | ribosomal protein L12 | -0.0312308 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0307861 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0306605 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0293145 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0292121 |
| CADM2 | cell adhesion molecule 2 | -0.0279293 |
| POTEF | POTE ankyrin domain family, member F | -0.0269803 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0267453 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.02626 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0253874 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0247317 |
| PLSCR1 | phospholipid scramblase 1 | -0.0245394 |
| HLA-B | major histocompatibility complex, class I, B | -0.0245191 |
| CD44 | CD44 molecule (Indian blood group) | -0.0244418 |
| SP100 | SP100 nuclear antigen | -0.0243642 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0238708 |
| RPL23 | ribosomal protein L23 | -0.0219765 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0218157 |
| ENO1 | enolase 1, (alpha) | -0.0217443 |
| HMGB1 | high mobility group box 1 | -0.0216416 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0211162 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0197938 |
| RPL38 | ribosomal protein L38 | -0.0190897 |
| YBX3 | Y box binding protein 3 | -0.0182742 |
| RPL36 | ribosomal protein L36 | -0.0182395 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0182112 |
| RPL8 | ribosomal protein L8 | -0.017859 |
| YBX1 | Y box binding protein 1 | -0.0176992 |
| RPS19 | ribosomal protein S19 | -0.0175334 |
| TFRC | transferrin receptor | -0.0175074 |
| RUNX1 | runt-related transcription factor 1 | -0.017452 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0173449 |
| RPS6 | ribosomal protein S6 | -0.0171892 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.016435 |
| RPLP1 | ribosomal protein, large, P1 | -0.0163037 |
| RPS4X | ribosomal protein S4, X-linked | -0.0154142 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0148897 |
| PMP22 | peripheral myelin protein 22 | -0.0148811 |
| OSMR | oncostatin M receptor | -0.0146806 |
| RPS8 | ribosomal protein S8 | -0.0146288 |
| RPL35A | ribosomal protein L35a | -0.0146084 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0144943 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0142346 |
| EGR1 | early growth response 1 | -0.0141321 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0138111 |
| CDK6 | cyclin-dependent kinase 6 | -0.0135739 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0135493 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0134558 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0133195 |
| RPS3 | ribosomal protein S3 | -0.0131287 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.013125 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0130794 |
| RGS4 | regulator of G-protein signaling 4 | -0.0130102 |
| RPL4 | ribosomal protein L4 | -0.0129964 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0129498 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0129429 |
| TUBB | tubulin, beta class I | -0.0129169 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0127444 |
| UBB | ubiquitin B | -0.0126509 |
| RPL31 | ribosomal protein L31 | -0.0125625 |
| SDC4 | syndecan 4 | -0.0123257 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0122673 |
| BSG | basigin (Ok blood group) | -0.0119809 |
| RPL19 | ribosomal protein L19 | -0.0119366 |
| MT1X | metallothionein 1X | -0.0118677 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0117337 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0117061 |
| PKM | pyruvate kinase, muscle | -0.0116784 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0116764 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0116007 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0115606 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0115467 |
| RPLP0 | ribosomal protein, large, P0 | -0.0115221 |
| RPL35 | ribosomal protein L35 | -0.0113311 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0113081 |
| RPS17 | ribosomal protein S17 | -0.0112178 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0110553 |
| SRGN | serglycin | -0.0110508 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0109974 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0107974 |
| RPS5 | ribosomal protein S5 | -0.0107287 |
| RPS23 | ribosomal protein S23 | -0.0106373 |
| IFRD1 | interferon-related developmental regulator 1 | -0.01062 |
| ADAR | adenosine deaminase, RNA-specific | -0.0106026 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0105227 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.010512 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0105078 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.010434 |
| S100A9 | S100 calcium binding protein A9 | -0.0104054 |
| TGM2 | transglutaminase 2 | -0.0103005 |
| RPS2 | ribosomal protein S2 | -0.0102598 |
