| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.11564 |
| MCL1 | myeloid cell leukemia 1 | 0.114671 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.112352 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0953705 |
| NDRG1 | N-myc downstream regulated 1 | 0.0886575 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0855925 |
| MKI67 | marker of proliferation Ki-67 | 0.0700753 |
| MT2A | metallothionein 2A | 0.0678742 |
| FAM13A | family with sequence similarity 13, member A | 0.0540382 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0534706 |
| SPAG9 | sperm associated antigen 9 | 0.051742 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0477892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0468227 |
| ARRDC3 | arrestin domain containing 3 | 0.0467047 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0462491 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0455555 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0449162 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0443418 |
| UBC | ubiquitin C | 0.043441 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0429915 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0422267 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0417985 |
| ZNF292 | zinc finger protein 292 | 0.0410833 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0404371 |
| EGFR | epidermal growth factor receptor | 0.0398172 |
| CCNL1 | cyclin L1 | 0.0379588 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0368554 |
| LAMB3 | laminin, beta 3 | 0.0367473 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0362418 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0359564 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0359069 |
| NGLY1 | N-glycanase 1 | 0.0354377 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.034382 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0333904 |
| TMEM165 | transmembrane protein 165 | 0.0326021 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0324954 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0324468 |
| B2M | beta-2-microglobulin | 0.031699 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0314523 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0310702 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0307643 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0303364 |
| FRY | furry homolog (Drosophila) | 0.0302752 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0297286 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0294376 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0291221 |
| OGA | O-GlcNAcase | 0.0288928 |
| CES1 | carboxylesterase 1 | 0.0287936 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0284679 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0284216 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0283954 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0282 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0280575 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0276015 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0275598 |
| PTEN | phosphatase and tensin homolog | 0.0273851 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0265352 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261666 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0259999 |
| FNIP1 | folliculin interacting protein 1 | 0.0258103 |
| ATP13A3 | ATPase type 13A3 | 0.0257631 |
| SETD5 | SET domain containing 5 | 0.0257549 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0256487 |
| ANKRD12 | ankyrin repeat domain 12 | 0.025613 |
| DSPP | dentin sialophosphoprotein | 0.025451 |
| MYO1B | myosin IB | 0.0251655 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0251139 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0250856 |
| CSTB | cystatin B (stefin B) | 0.025082 |
| SLMAP | sarcolemma associated protein | 0.0250697 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0249088 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0247273 |
| USP34 | ubiquitin specific peptidase 34 | 0.0245925 |
| TPD52 | tumor protein D52 | 0.0244333 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0242865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0241873 |
| MSN | moesin | 0.0237339 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0236437 |
| ANO6 | anoctamin 6 | 0.0236224 |
| YEATS2 | YEATS domain containing 2 | 0.0234049 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0232241 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0231674 |
| FAM193A | family with sequence similarity 193, member A | 0.022969 |
| SEPTIN2 | septin 2 | 0.0229092 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.022547 |
| SP3 | Sp3 transcription factor | 0.0224931 |
| SLTM | SAFB-like, transcription modulator | 0.0224497 |
| WASF2 | WAS protein family, member 2 | 0.0222061 |
| PDE8A | phosphodiesterase 8A | 0.0221792 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0221229 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0219241 |
| CCNI | cyclin I | 0.0217773 |
| JMJD1C | jumonji domain containing 1C | 0.0217198 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0216957 |
| ZNF638 | zinc finger protein 638 | 0.0215855 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0214137 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0213096 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0213001 |
| PYGL | phosphorylase, glycogen, liver | 0.0212044 |
| COPA | coatomer protein complex, subunit alpha | 0.0211839 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0901262 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0864086 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0827382 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0793014 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0791527 |
| ASPH | aspartate beta-hydroxylase | -0.075328 |
| TXNRD1 | thioredoxin reductase 1 | -0.0701943 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0625943 |
| GRAMD1B | GRAM domain containing 1B | -0.055282 |
| MYOF | myoferlin | -0.0532083 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0505663 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0470495 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0456651 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0456554 |
| ACTG1 | actin gamma 1 | -0.0437942 |
| ANXA2 | annexin A2 | -0.0411272 |
| KRT7 | keratin 7, type II | -0.0411272 |
| CCND1 | cyclin D1 | -0.0409696 |
| RPS24 | ribosomal protein S24 | -0.0392703 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0377443 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374659 |
| RPS25 | ribosomal protein S25 | -0.0371179 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0348187 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0347605 |
| AHNAK | AHNAK nucleoprotein | -0.0345739 |
| S100A10 | S100 calcium binding protein A10 | -0.0329377 |
| RPL35A | ribosomal protein L35a | -0.032873 |
| KRT18 | keratin 18, type I | -0.0327303 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0323473 |
| RPLP1 | ribosomal protein, large, P1 | -0.03024 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0302226 |
| INTS6 | integrator complex subunit 6 | -0.0300453 |
| EGR1 | early growth response 1 | -0.0293346 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0287558 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0283482 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0281894 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0278844 |
| IER3 | immediate early response 3 | -0.0277136 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.02756 |
| TES | testin LIM domain protein | -0.027128 |
| ENO1 | enolase 1, (alpha) | -0.026341 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0262797 |
| RPS27A | ribosomal protein S27a | -0.0257252 |
| HOMER1 | homer scaffolding protein 1 | -0.0255231 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0252175 |
| SMYD3 | SET and MYND domain containing 3 | -0.0243742 |
| RPL19 | ribosomal protein L19 | -0.0227512 |
| RAB10 | RAB10, member RAS oncogene family | -0.0226893 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.022285 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0220405 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0219145 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.021712 |
| SCEL | sciellin | -0.0217017 |
| RPL34 | ribosomal protein L34 | -0.0216406 |
| RPL8 | ribosomal protein L8 | -0.0214849 |
| RPS6 | ribosomal protein S6 | -0.0212906 |
| GM2A | GM2 ganglioside activator | -0.02127 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0207125 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0207052 |
| AGR2 | anterior gradient 2 | -0.0206378 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0205934 |
| CST3 | cystatin C | -0.0203454 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0203146 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0201326 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0200888 |
| CUX1 | cut-like homeobox 1 | -0.0200435 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0193946 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0193588 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0193547 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0190608 |
| CANX | calnexin | -0.0189863 |
| FOXP1 | forkhead box P1 | -0.0189537 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0189519 |
| MAP7 | microtubule-associated protein 7 | -0.0188268 |
| RASAL2 | RAS protein activator like 2 | -0.0187396 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0187151 |
| RPL12 | ribosomal protein L12 | -0.0186913 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.01854 |
| NABP1 | nucleic acid binding protein 1 | -0.0184321 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0182022 |
| RPL4 | ribosomal protein L4 | -0.0181893 |
| GNAS | GNAS complex locus | -0.0178566 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0177399 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0176292 |
| ARF1 | ADP-ribosylation factor 1 | -0.0175017 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0174913 |
| EHBP1 | EH domain binding protein 1 | -0.0173203 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0173002 |
| HDLBP | high density lipoprotein binding protein | -0.0172785 |
| FTL | ferritin, light polypeptide | -0.0172723 |
| RPL37 | ribosomal protein L37 | -0.0172026 |
| DENND5B | DENN/MADD domain containing 5B | -0.0171845 |
| RPS8 | ribosomal protein S8 | -0.0170333 |
| RNF213 | ring finger protein 213 | -0.0168292 |
| RPLP0 | ribosomal protein, large, P0 | -0.0167397 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.016378 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.016304 |
| NTN4 | netrin 4 | -0.0162867 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.016098 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0160888 |
