| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111875 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.075146 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0697855 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0643786 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0563316 |
| RPS12 | ribosomal protein S12 | 0.0561187 |
| RPLP1 | ribosomal protein, large, P1 | 0.051877 |
| NPSR1 | neuropeptide S receptor 1 | 0.05091 |
| GPC6 | glypican 6 | 0.0505543 |
| RORA | RAR-related orphan receptor A | 0.0474398 |
| DSTN | destrin (actin depolymerizing factor) | 0.046879 |
| RPL12 | ribosomal protein L12 | 0.046577 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0437807 |
| RPS6 | ribosomal protein S6 | 0.0433022 |
| ZNF292 | zinc finger protein 292 | 0.0432911 |
| PTK2 | protein tyrosine kinase 2 | 0.0429493 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0423749 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0418263 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0401739 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0399118 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0391704 |
| RPL23 | ribosomal protein L23 | 0.039104 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0376205 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364959 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0358161 |
| CD109 | CD109 molecule | 0.035728 |
| SETD5 | SET domain containing 5 | 0.0353938 |
| GOLGA4 | golgin A4 | 0.0353355 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0349096 |
| RPS27A | ribosomal protein S27a | 0.0337214 |
| NBAS | neuroblastoma amplified sequence | 0.0335345 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0326685 |
| JAK1 | Janus kinase 1 | 0.0325092 |
| GDA | guanine deaminase | 0.0313916 |
| ACTG1 | actin gamma 1 | 0.0313537 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0312906 |
| FTL | ferritin, light polypeptide | 0.0312748 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0312047 |
| RPL11 | ribosomal protein L11 | 0.030982 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.030764 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0306055 |
| GNAS | GNAS complex locus | 0.0300825 |
| NUP58 | nucleoporin 58 | 0.0296445 |
| RTN3 | reticulon 3 | 0.028765 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0286728 |
| S100A6 | S100 calcium binding protein A6 | 0.0285192 |
| B2M | beta-2-microglobulin | 0.0284853 |
| CCDC47 | coiled-coil domain containing 47 | 0.028423 |
| RTN4 | reticulon 4 | 0.0283123 |
| CANX | calnexin | 0.0282408 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0280637 |
| EFNA5 | ephrin-A5 | 0.0280617 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0280278 |
| PCBP2 | poly(rC) binding protein 2 | 0.0279565 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.027909 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0277231 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0275858 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.027405 |
| CLTC | clathrin, heavy chain (Hc) | 0.0269807 |
| IRS2 | insulin receptor substrate 2 | 0.0268303 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0267812 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0265737 |
| RBM39 | RNA binding motif protein 39 | 0.0261798 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0261721 |
| TMC5 | transmembrane channel-like 5 | 0.0259384 |
| PTMA | prothymosin, alpha | 0.0257062 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0255462 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0251482 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0244447 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0241941 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0238278 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0235868 |
| ATP13A3 | ATPase type 13A3 | 0.0234366 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0233566 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0231758 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0231096 |
| CCDC88A | coiled-coil domain containing 88A | 0.0228241 |
| MSI2 | musashi RNA-binding protein 2 | 0.0228086 |
| FAM193A | family with sequence similarity 193, member A | 0.0227762 |
| AHI1 | Abelson helper integration site 1 | 0.022737 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0225542 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.022547 |
| DIDO1 | death inducer-obliterator 1 | 0.0225284 |
| MATR3 | matrin 3 | 0.0224748 |
| NFIB | nuclear factor I/B | 0.0222935 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0221291 |
| INTS6 | integrator complex subunit 6 | 0.0215986 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0212859 |
| RLF | rearranged L-myc fusion | 0.0210358 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0207914 |
| APP | amyloid beta (A4) precursor protein | 0.020682 |
| FN1 | fibronectin 1 | 0.020369 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0202989 |
| NTN4 | netrin 4 | 0.0202881 |
| H1-0 | H1.0 linker histone | 0.0202321 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0202296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0202 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0201391 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0201188 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0200901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.139872 |
| MYO1E | myosin IE | -0.0981283 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0908831 |
| LAMB3 | laminin, beta 3 | -0.0857668 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0626919 |
| LAMC2 | laminin, gamma 2 | -0.0619677 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0612443 |
| TXNRD1 | thioredoxin reductase 1 | -0.0584494 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0579518 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0568224 |
| VCL | vinculin | -0.0567087 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0533429 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0520663 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0513783 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0509891 |
| OSMR | oncostatin M receptor | -0.05013 |
| SVIL | supervillin | -0.0495959 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0482325 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0464214 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0459707 |
| KYNU | kynureninase | -0.0453652 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0451762 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0432035 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0430394 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0430342 |
| ATOSA | atos homolog A | -0.0414231 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0405662 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0394546 |
| ABHD17C | abhydrolase domain containing 17C | -0.0391963 |
| ZNF217 | zinc finger protein 217 | -0.0388173 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.038232 |
| VCAN | versican | -0.0382274 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0375553 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0375462 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0373507 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0373271 |
| CDCP1 | CUB domain containing protein 1 | -0.0361107 |
| RNF213 | ring finger protein 213 | -0.0357532 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0346493 |
| OGA | O-GlcNAcase | -0.034326 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0342585 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0337389 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0334777 |
| ANXA2 | annexin A2 | -0.0331746 |
| FOXP1 | forkhead box P1 | -0.0331001 |
| POTEF | POTE ankyrin domain family, member F | -0.0330191 |
| INHBA | inhibin, beta A | -0.0327723 |
| MYO5B | myosin VB | -0.0321738 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0320404 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0318676 |
| RBM47 | RNA binding motif protein 47 | -0.0317904 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.031787 |
| GLIS3 | GLIS family zinc finger 3 | -0.0311825 |
| PERP | PERP, TP53 apoptosis effector | -0.0309931 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0309458 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0307637 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0306427 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0304171 |
| PRSS23 | protease, serine, 23 | -0.0293512 |
| AK1 | adenylate kinase 1 | -0.0293413 |
| BCL2L1 | BCL2-like 1 | -0.0291496 |
| S100A10 | S100 calcium binding protein A10 | -0.0287462 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.028104 |
| CLDN4 | claudin 4 | -0.0269149 |
| FNIP1 | folliculin interacting protein 1 | -0.0266385 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0264686 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0264063 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0262831 |
| MCL1 | myeloid cell leukemia 1 | -0.0261604 |
| GRAMD2B | GRAM domain containing 2B | -0.0261325 |
| IGF2 | insulin-like growth factor 2 | -0.0261057 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0261023 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0257838 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0255352 |
| MYO5C | myosin VC | -0.0253747 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.025151 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0251211 |
| JUP | junction plakoglobin | -0.0250956 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0249659 |
| EXOC4 | exocyst complex component 4 | -0.0246865 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0246719 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0246485 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0246256 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0246104 |
| GRAMD1B | GRAM domain containing 1B | -0.0245153 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.024453 |
| PHIP | pleckstrin homology domain interacting protein | -0.0241738 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0238501 |
| TLK1 | tousled-like kinase 1 | -0.023828 |
| NBEA | neurobeachin | -0.0235645 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0234551 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0233035 |
| KRT17 | keratin 17, type I | -0.02294 |
| AHNAK | AHNAK nucleoprotein | -0.0227656 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0227644 |
| DSPP | dentin sialophosphoprotein | -0.0226436 |
| SP100 | SP100 nuclear antigen | -0.0225963 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0224196 |
| FBXO11 | F-box protein 11 | -0.022401 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0218725 |
