| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.214691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.174846 |
| MCL1 | myeloid cell leukemia 1 | 0.104454 |
| RAD51B | RAD51 paralog B | 0.0983574 |
| COPA | coatomer protein complex, subunit alpha | 0.0824467 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0823545 |
| UBC | ubiquitin C | 0.0767714 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0762348 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0746569 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0692258 |
| VMP1 | vacuole membrane protein 1 | 0.0684211 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0643179 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.061565 |
| VIM | vimentin | 0.0594297 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0569275 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.056184 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0547911 |
| SMAD3 | SMAD family member 3 | 0.0527861 |
| WASF2 | WAS protein family, member 2 | 0.0520315 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0513068 |
| RPL37 | ribosomal protein L37 | 0.0498055 |
| CCNL1 | cyclin L1 | 0.04923 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0466519 |
| ACTN1 | actinin, alpha 1 | 0.0453777 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0434691 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0431077 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0421354 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0416943 |
| XPOT | exportin, tRNA | 0.0405623 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0405289 |
| H1-0 | H1.0 linker histone | 0.0403486 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0397852 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0394614 |
| SETD5 | SET domain containing 5 | 0.0391839 |
| NF1 | neurofibromin 1 | 0.0389215 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0377781 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0377355 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0375835 |
| MT2A | metallothionein 2A | 0.0375445 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0367993 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0367779 |
| EGFR | epidermal growth factor receptor | 0.0360946 |
| MSN | moesin | 0.0358497 |
| PGK1 | phosphoglycerate kinase 1 | 0.0355336 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0350638 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.034947 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0347346 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0339186 |
| RPS27 | ribosomal protein S27 | 0.0338965 |
| TXNRD1 | thioredoxin reductase 1 | 0.0332658 |
| BBX | bobby sox homolog (Drosophila) | 0.0328373 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0326097 |
| RNF213 | ring finger protein 213 | 0.0322428 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0319585 |
| TPI1 | triosephosphate isomerase 1 | 0.0318535 |
| PRELID3B | PRELI domain containing 3B | 0.031717 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0316213 |
| TMEM165 | transmembrane protein 165 | 0.0314425 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0310251 |
| FMNL2 | formin-like 2 | 0.0309214 |
| TPM2 | tropomyosin 2 (beta) | 0.0308381 |
| RPL36A | ribosomal protein L36a | 0.0304586 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0302953 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0301863 |
| FNBP4 | formin binding protein 4 | 0.0301849 |
| ATXN2 | ataxin 2 | 0.0300909 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0299907 |
| CEP250 | centrosomal protein 250kDa | 0.029567 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0292521 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0289837 |
| PPP1R21 | protein phosphatase 1, regulatory subunit 21 | 0.0287357 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0286465 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0285425 |
| DENND1A | DENN/MADD domain containing 1A | 0.0283562 |
| RBMX | RNA binding motif protein, X-linked | 0.028214 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0279703 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0274916 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0274554 |
| LDHB | lactate dehydrogenase B | 0.027369 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.026823 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0268207 |
| TBC1D15 | TBC1 domain family, member 15 | 0.026795 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0267902 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0267319 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0267047 |
| RSF1 | remodeling and spacing factor 1 | 0.0266515 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0265042 |
| FTL | ferritin, light polypeptide | 0.0264635 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0262165 |
| TMEM39A | transmembrane protein 39A | 0.0259651 |
| USP36 | ubiquitin specific peptidase 36 | 0.025954 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0257858 |
| PYGL | phosphorylase, glycogen, liver | 0.0257828 |
| PTK2 | protein tyrosine kinase 2 | 0.0255847 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254712 |
| TULP3 | tubby like protein 3 | 0.0253334 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0252449 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0250067 |
| ZNF292 | zinc finger protein 292 | 0.0248051 |
| SP3 | Sp3 transcription factor | 0.0247062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.201836 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.130624 |
| YBX3 | Y box binding protein 3 | -0.0919774 |
| GRAMD1B | GRAM domain containing 1B | -0.0793085 |
| TMSB10 | thymosin beta 10 | -0.0751285 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0680736 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0645464 |
| RPS2 | ribosomal protein S2 | -0.0642623 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0621806 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0554189 |
| CENPF | centromere protein F, 350/400kDa | -0.0529898 |
| RPL38 | ribosomal protein L38 | -0.0517457 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0507667 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0503464 |
| HLA-B | major histocompatibility complex, class I, B | -0.0475426 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0458531 |
| POTEF | POTE ankyrin domain family, member F | -0.0456315 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.045514 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.044568 |
| OSMR | oncostatin M receptor | -0.0442549 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0441114 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0432971 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0432875 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0381228 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0380268 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0374223 |
| RPS21 | ribosomal protein S21 | -0.0372211 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.0360367 |
| CCND2 | cyclin D2 | -0.036001 |
| PTMA | prothymosin, alpha | -0.0357837 |
| MATR3 | matrin 3 | -0.0355257 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0353688 |
| DEK | DEK proto-oncogene | -0.035278 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0341592 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0338973 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0336473 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.033592 |
| FUS | FUS RNA binding protein | -0.0320956 |
| NLGN1 | neuroligin 1 | -0.0317467 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0315576 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0315035 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0314836 |
| SEPTIN7 | septin 7 | -0.0313677 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0309255 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0308495 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0304624 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0300126 |
| RTN4 | reticulon 4 | -0.029894 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0296834 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0294116 |
| ATP11A | ATPase, class VI, type 11A | -0.0286467 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0282556 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0273605 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0272338 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0268461 |
| ADAR | adenosine deaminase, RNA-specific | -0.0264999 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0264857 |
| CCND1 | cyclin D1 | -0.0263277 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0263264 |
| ABI2 | abl-interactor 2 | -0.0262017 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0261281 |
| GNAS | GNAS complex locus | -0.0259402 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0254025 |
| STK4 | serine/threonine kinase 4 | -0.0253288 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0252605 |
| PHIP | pleckstrin homology domain interacting protein | -0.0250701 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0248044 |
| RAB10 | RAB10, member RAS oncogene family | -0.0247331 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0246323 |
| IER3 | immediate early response 3 | -0.0246036 |
| EXOC4 | exocyst complex component 4 | -0.0246024 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0242203 |
| CALD1 | caldesmon 1 | -0.0239756 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0238497 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0238371 |
| BMP5 | bone morphogenetic protein 5 | -0.0238362 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0236553 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0236438 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0235092 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0233482 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0233011 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0231619 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0229636 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0229606 |
| S100A10 | S100 calcium binding protein A10 | -0.0228696 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0228694 |
| WBP11 | WW domain binding protein 11 | -0.0227151 |
| CUL4B | cullin 4B | -0.022713 |
| RRM2 | ribonucleotide reductase M2 | -0.0223296 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0221743 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0220944 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0220114 |
| RPL6 | ribosomal protein L6 | -0.0220023 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0219071 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0216994 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0216507 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0216151 |
| TPX2 | TPX2, microtubule-associated | -0.0214462 |
| PDE10A | phosphodiesterase 10A | -0.0213757 |
| RPS29 | ribosomal protein S29 | -0.0213137 |
