| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.229523 |
| FN1 | fibronectin 1 | 0.223867 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.177988 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.170448 |
| NDRG1 | N-myc downstream regulated 1 | 0.159223 |
| FNDC3B | fibronectin type III domain containing 3B | 0.118784 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.114684 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.105687 |
| ASPH | aspartate beta-hydroxylase | 0.0982074 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0888517 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0786481 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0776059 |
| PGK1 | phosphoglycerate kinase 1 | 0.0726556 |
| RNF145 | ring finger protein 145 | 0.0715749 |
| TFG | TRK-fused gene | 0.0704036 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.070376 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0697701 |
| LAMB3 | laminin, beta 3 | 0.0678366 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0663083 |
| GOLGA4 | golgin A4 | 0.064173 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0634551 |
| PTMA | prothymosin, alpha | 0.0630048 |
| FAM13A | family with sequence similarity 13, member A | 0.061976 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.058701 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.05736 |
| SLMAP | sarcolemma associated protein | 0.0572641 |
| PTK2 | protein tyrosine kinase 2 | 0.0565963 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0564495 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0556157 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0540748 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0532478 |
| UBC | ubiquitin C | 0.0521128 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0518365 |
| LAMC2 | laminin, gamma 2 | 0.0516603 |
| CCNL1 | cyclin L1 | 0.0510049 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0509258 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0502842 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0502439 |
| ARRDC3 | arrestin domain containing 3 | 0.0493569 |
| FAM3C | family with sequence similarity 3, member C | 0.049352 |
| LDHA | lactate dehydrogenase A | 0.0491145 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0483574 |
| MXD1 | MAX dimerization protein 1 | 0.0483139 |
| TOP1 | topoisomerase (DNA) I | 0.0477484 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0474309 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0445922 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0445411 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0443455 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0441354 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0440071 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0439421 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0434956 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0430398 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0427683 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0426527 |
| WAC | WW domain containing adaptor with coiled-coil | 0.04247 |
| COPA | coatomer protein complex, subunit alpha | 0.0423032 |
| CDC73 | cell division cycle 73 | 0.0419345 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0418632 |
| SETD5 | SET domain containing 5 | 0.0418334 |
| NUP58 | nucleoporin 58 | 0.0417789 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0416784 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0416714 |
| USP3 | ubiquitin specific peptidase 3 | 0.0416551 |
| MYO6 | myosin VI | 0.0416276 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0398523 |
| RBM39 | RNA binding motif protein 39 | 0.0396932 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0396378 |
| PARD3 | par-3 family cell polarity regulator | 0.039567 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0395063 |
| RLF | rearranged L-myc fusion | 0.0392866 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0392533 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0391706 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0390277 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0385852 |
| YTHDC1 | YTH domain containing 1 | 0.0384069 |
| ZNF292 | zinc finger protein 292 | 0.038395 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0381078 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0379355 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0379227 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0374924 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0372458 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0371074 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0365508 |
| CANX | calnexin | 0.0364575 |
| CALR | calreticulin | 0.0358099 |
| SPAG9 | sperm associated antigen 9 | 0.0356379 |
| ATP13A3 | ATPase type 13A3 | 0.0355105 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0354165 |
| RTN4 | reticulon 4 | 0.0351974 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0351945 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0348901 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0348122 |
| ANXA1 | annexin A1 | 0.0334903 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0332667 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0332664 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0332344 |
| FAM162A | family with sequence similarity 162, member A | 0.0331052 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0330581 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0330219 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.096739 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0901378 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0832 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0826321 |
| TMSB10 | thymosin beta 10 | -0.0819582 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0739438 |
| POTEF | POTE ankyrin domain family, member F | -0.0715044 |
| KRT7 | keratin 7, type II | -0.0528983 |
| EXT1 | exostosin glycosyltransferase 1 | -0.052876 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.050012 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0494421 |
| EFNA5 | ephrin-A5 | -0.0478197 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0465049 |
| RNF213 | ring finger protein 213 | -0.0461797 |
| MX2 | MX dynamin-like GTPase 2 | -0.041472 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0406358 |
| NAV2 | neuron navigator 2 | -0.0406183 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0405755 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0404543 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0400316 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0369713 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0366942 |
| CCND1 | cyclin D1 | -0.0363419 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0358167 |
| RPL8 | ribosomal protein L8 | -0.0346325 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0346077 |
| VCL | vinculin | -0.0325167 |
| RIGI | RNA sensor RIG-I | -0.031734 |
| ATXN1 | ataxin 1 | -0.0316696 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0311388 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0310208 |
| RPS8 | ribosomal protein S8 | -0.0309569 |
| RPS29 | ribosomal protein S29 | -0.0306959 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0296466 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0289256 |
| MX1 | MX dynamin-like GTPase 1 | -0.0287331 |
| INTS6 | integrator complex subunit 6 | -0.0284763 |
| ETV6 | ets variant 6 | -0.0284001 |
| RPS19 | ribosomal protein S19 | -0.0282969 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0275204 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0274401 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271127 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0268567 |
| RAD51B | RAD51 paralog B | -0.0261966 |
| TBCA | tubulin folding cofactor A | -0.0258725 |
| RPL19 | ribosomal protein L19 | -0.0254909 |
| ENO1 | enolase 1, (alpha) | -0.0254874 |
| LMNA | lamin A/C | -0.0253294 |
| GOLGB1 | golgin B1 | -0.0252403 |
| RPL35 | ribosomal protein L35 | -0.024992 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0248981 |
| FBXO32 | F-box protein 32 | -0.0243699 |
| KRT18 | keratin 18, type I | -0.0239819 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0238442 |
| FNIP1 | folliculin interacting protein 1 | -0.0232919 |
| S100A10 | S100 calcium binding protein A10 | -0.0232041 |
| RBM47 | RNA binding motif protein 47 | -0.0229783 |
| SON | SON DNA binding protein | -0.0226799 |
| RPL28 | ribosomal protein L28 | -0.0225703 |
| RPLP2 | ribosomal protein, large, P2 | -0.0218106 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0216137 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0215271 |
| SVIL | supervillin | -0.0213995 |
| PALLD | palladin, cytoskeletal associated protein | -0.0213643 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0212442 |
| EGR1 | early growth response 1 | -0.0212132 |
| S100A9 | S100 calcium binding protein A9 | -0.0207946 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0207175 |
| LAP3 | leucine aminopeptidase 3 | -0.0205497 |
| KRT19 | keratin 19, type I | -0.0204735 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0204635 |
| RPL37A | ribosomal protein L37a | -0.0201399 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0198961 |
| RPS3 | ribosomal protein S3 | -0.0196115 |
| RPL35A | ribosomal protein L35a | -0.0195579 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.019503 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0195024 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0194175 |
| NABP1 | nucleic acid binding protein 1 | -0.019248 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0191436 |
| FHIT | fragile histidine triad | -0.0190467 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.01904 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0188132 |
| RPL36 | ribosomal protein L36 | -0.0188072 |
| PLSCR1 | phospholipid scramblase 1 | -0.0186841 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0186795 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0185964 |
| EXOC4 | exocyst complex component 4 | -0.0185081 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0183854 |
| RPS17 | ribosomal protein S17 | -0.018346 |
| RPL31 | ribosomal protein L31 | -0.0182657 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0182211 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0181836 |
| RPS5 | ribosomal protein S5 | -0.0179961 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0176637 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0176617 |
| MGLL | monoglyceride lipase | -0.0175122 |
| RAI14 | retinoic acid induced 14 | -0.0174063 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0173484 |
| NF1 | neurofibromin 1 | -0.0173259 |
