| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.198628 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.175792 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.171519 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.146375 |
| PTK2 | protein tyrosine kinase 2 | 0.146305 |
| FLNB | filamin B, beta | 0.134973 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.129533 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.12595 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.115886 |
| GOLGA4 | golgin A4 | 0.114604 |
| ATP13A3 | ATPase type 13A3 | 0.114011 |
| FN1 | fibronectin 1 | 0.110447 |
| LDHA | lactate dehydrogenase A | 0.100832 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0990536 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0965285 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0903273 |
| DTNA | dystrobrevin, alpha | 0.086606 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0836389 |
| SFTPA2 | surfactant protein A2 | 0.0792934 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0747857 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0745751 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0730655 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0720326 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.070515 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0704605 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0700785 |
| ASPH | aspartate beta-hydroxylase | 0.0692097 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0681562 |
| CD44 | CD44 molecule (Indian blood group) | 0.0664165 |
| SBF2 | SET binding factor 2 | 0.0662524 |
| STC1 | stanniocalcin 1 | 0.0639899 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0636905 |
| PTMA | prothymosin, alpha | 0.062911 |
| OGA | O-GlcNAcase | 0.0622975 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0593097 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0577832 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0536685 |
| CCNI | cyclin I | 0.0528891 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0528553 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0507475 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0502827 |
| STAG2 | stromal antigen 2 | 0.0479276 |
| ENO1 | enolase 1, (alpha) | 0.0474654 |
| NDRG1 | N-myc downstream regulated 1 | 0.0452561 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0443438 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0439324 |
| SPAG9 | sperm associated antigen 9 | 0.0439208 |
| ACTG1 | actin gamma 1 | 0.0433007 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0422018 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0421379 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0417 |
| ZNF292 | zinc finger protein 292 | 0.0414634 |
| NUP58 | nucleoporin 58 | 0.0409677 |
| RPS3 | ribosomal protein S3 | 0.0400983 |
| RPL37 | ribosomal protein L37 | 0.0385668 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0374415 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0357895 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0349153 |
| MYO1E | myosin IE | 0.0338757 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0329563 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0313925 |
| RPS6 | ribosomal protein S6 | 0.0309128 |
| RSF1 | remodeling and spacing factor 1 | 0.0308034 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0305012 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0303852 |
| RPL19 | ribosomal protein L19 | 0.028423 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0279743 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0274251 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0271152 |
| RPS8 | ribosomal protein S8 | 0.0263906 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0254771 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0250026 |
| ITGA6 | integrin, alpha 6 | 0.0244304 |
| USP34 | ubiquitin specific peptidase 34 | 0.0243516 |
| RBM39 | RNA binding motif protein 39 | 0.023737 |
| DST | dystonin | 0.0235161 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.021881 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0205931 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0205677 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0194947 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0181842 |
| FTL | ferritin, light polypeptide | 0.017175 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0165487 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0160819 |
| EZR | ezrin | 0.014041 |
| VIM | vimentin | 0.0125131 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.011928 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0114029 |
| WASF2 | WAS protein family, member 2 | 0.0112137 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0107679 |
| COPA | coatomer protein complex, subunit alpha | 0.00890716 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0086859 |
| RPLP2 | ribosomal protein, large, P2 | 0.0080818 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00775643 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00696753 |
| HDLBP | high density lipoprotein binding protein | 0.00669226 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00625985 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00622713 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00612436 |
| TMSB10 | thymosin beta 10 | 0.00487776 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.152019 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.125507 |
| RBM25 | RNA binding motif protein 25 | -0.119119 |
| CDH13 | cadherin 13 | -0.110159 |
| PDE10A | phosphodiesterase 10A | -0.0968817 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0946103 |
| EFNA5 | ephrin-A5 | -0.0903079 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0899466 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0893451 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.083028 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0816796 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0797252 |
| HMGA2 | high mobility group AT-hook 2 | -0.0784604 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0744923 |
| IGF2 | insulin-like growth factor 2 | -0.0738307 |
| RPL37A | ribosomal protein L37a | -0.0703494 |
| MT2A | metallothionein 2A | -0.0686622 |
| NF1 | neurofibromin 1 | -0.0684881 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0663433 |
| RPS25 | ribosomal protein S25 | -0.0654846 |
| RPS24 | ribosomal protein S24 | -0.0649806 |
| MORF4L2 | mortality factor 4 like 2 | -0.0626545 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.059275 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0589868 |
| SNX9 | sorting nexin 9 | -0.0586542 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0584547 |
| PARD3 | par-3 family cell polarity regulator | -0.0567806 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0565809 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.055631 |
| EGR1 | early growth response 1 | -0.0551209 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0548757 |
| MED13 | mediator complex subunit 13 | -0.0545557 |
| SP100 | SP100 nuclear antigen | -0.0542459 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0533519 |
| RPLP1 | ribosomal protein, large, P1 | -0.0530841 |
| RPL34 | ribosomal protein L34 | -0.0529832 |
| RPL26 | ribosomal protein L26 | -0.0519332 |
| B2M | beta-2-microglobulin | -0.0511204 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0491598 |
| COL5A1 | collagen, type V, alpha 1 | -0.0476948 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0474376 |
| VCL | vinculin | -0.0464259 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0463734 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0449414 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0426713 |
| RTN4 | reticulon 4 | -0.0419898 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0409885 |
| DIAPH2 | diaphanous-related formin 2 | -0.0392734 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0392217 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0373177 |
| RPL35A | ribosomal protein L35a | -0.0370081 |
| PRKCA | protein kinase C, alpha | -0.0362701 |
| CANX | calnexin | -0.0362112 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0361925 |
| MCL1 | myeloid cell leukemia 1 | -0.0358645 |
| LMO7 | LIM domain 7 | -0.0358435 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0352586 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0345331 |
| RPS12 | ribosomal protein S12 | -0.0341451 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0330784 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0326453 |
| RUNX1 | runt-related transcription factor 1 | -0.0320621 |
| PCBP2 | poly(rC) binding protein 2 | -0.0317236 |
| LAMB3 | laminin, beta 3 | -0.0313568 |
| JMJD1C | jumonji domain containing 1C | -0.0308599 |
| CALR | calreticulin | -0.0299727 |
| CDK6 | cyclin-dependent kinase 6 | -0.0291681 |
| MED13L | mediator complex subunit 13-like | -0.0284856 |
| SMYD3 | SET and MYND domain containing 3 | -0.0284468 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0282191 |
| LMNA | lamin A/C | -0.0278224 |
| FMNL2 | formin-like 2 | -0.02752 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0251919 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0251267 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0244404 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0241095 |
| KIF5B | kinesin family member 5B | -0.0231355 |
| SETD5 | SET domain containing 5 | -0.0219972 |
| RPS19 | ribosomal protein S19 | -0.0213075 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0210772 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0198845 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0196656 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0193811 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.01935 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.019085 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0182025 |
| RPL12 | ribosomal protein L12 | -0.0169075 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.0164576 |
| RPS16 | ribosomal protein S16 | -0.0160218 |
| PGK1 | phosphoglycerate kinase 1 | -0.0147213 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0140988 |
| RPL23 | ribosomal protein L23 | -0.013787 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.01254 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0101592 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00986373 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.00981115 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00938451 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00904364 |
| MXD1 | MAX dimerization protein 1 | -0.00850614 |
| AFF4 | AF4/FMR2 family, member 4 | -0.00496901 |
