| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.129153 |
| PEG10 | paternally expressed 10 | 0.107269 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.102383 |
| PTMA | prothymosin, alpha | 0.0979456 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0901593 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0834609 |
| SPAG9 | sperm associated antigen 9 | 0.0797379 |
| RHEB | Ras homolog enriched in brain | 0.0750214 |
| ITGAV | integrin, alpha V | 0.0716712 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0708018 |
| ZNF292 | zinc finger protein 292 | 0.0693554 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0670869 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.06699 |
| TSC22D2 | TSC22 domain family, member 2 | 0.065589 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0652873 |
| EMP1 | epithelial membrane protein 1 | 0.0618146 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0568952 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.052498 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0510855 |
| MED13L | mediator complex subunit 13-like | 0.0506343 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0503973 |
| MYO10 | myosin X | 0.048231 |
| CALR | calreticulin | 0.0479563 |
| USP3 | ubiquitin specific peptidase 3 | 0.0479041 |
| STAG2 | stromal antigen 2 | 0.0459251 |
| CDC73 | cell division cycle 73 | 0.0458141 |
| WDR43 | WD repeat domain 43 | 0.0456415 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0454605 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0451674 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0443911 |
| TPR | translocated promoter region, nuclear basket protein | 0.0439494 |
| MATR3 | matrin 3 | 0.0436991 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0434037 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0431218 |
| RBM39 | RNA binding motif protein 39 | 0.0430494 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0427049 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0424656 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0422816 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0415029 |
| NOP58 | NOP58 ribonucleoprotein | 0.0401694 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0397609 |
| DSCAM | Down syndrome cell adhesion molecule | 0.039484 |
| SP3 | Sp3 transcription factor | 0.038785 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0380505 |
| DST | dystonin | 0.0377891 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0377841 |
| NCKAP1 | NCK-associated protein 1 | 0.0373471 |
| XPO1 | exportin 1 | 0.0369017 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0363267 |
| CCNL1 | cyclin L1 | 0.036257 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0356692 |
| OGA | O-GlcNAcase | 0.035577 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0355691 |
| IPO7 | importin 7 | 0.0348827 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0344323 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0343933 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0337859 |
| DENND4A | DENN/MADD domain containing 4A | 0.0336508 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0335924 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0334905 |
| RPL7 | ribosomal protein L7 | 0.0334411 |
| CLTC | clathrin, heavy chain (Hc) | 0.0334321 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0334261 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0330629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0329847 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0327942 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0327722 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0325548 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0324397 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0324111 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0323455 |
| ACTN4 | actinin, alpha 4 | 0.0319552 |
| FMNL2 | formin-like 2 | 0.0317076 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0316254 |
| HMGB2 | high mobility group box 2 | 0.0312994 |
| HELZ | helicase with zinc finger | 0.0310515 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0310252 |
| TFG | TRK-fused gene | 0.0309783 |
| MEMO1 | mediator of cell motility 1 | 0.0309523 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.030947 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0308297 |
| CCNY | cyclin Y | 0.0306045 |
| SETD5 | SET domain containing 5 | 0.0304836 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0304468 |
| PLPP1 | phospholipid phosphatase 1 | 0.0304288 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0301265 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0300218 |
| CXADR | coxsackie virus and adenovirus receptor | 0.029993 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0298187 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0298116 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0297914 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.029572 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0295396 |
| RREB1 | ras responsive element binding protein 1 | 0.0294301 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0293456 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0291454 |
| ENAH | enabled homolog (Drosophila) | 0.0290636 |
| RAI1 | retinoic acid induced 1 | 0.0288729 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0287991 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0287354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.138163 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.113456 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0949557 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0926873 |
| VIM | vimentin | -0.091186 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0868179 |
| TENM3 | teneurin transmembrane protein 3 | -0.0813605 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0764658 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0725132 |
| PCDH9 | protocadherin 9 | -0.0722509 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0694696 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0691539 |
| ACTG1 | actin gamma 1 | -0.062988 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0578582 |
| ENO1 | enolase 1, (alpha) | -0.0540356 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0533505 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0486782 |
| TMSB10 | thymosin beta 10 | -0.0478425 |
| RPLP1 | ribosomal protein, large, P1 | -0.044749 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0445397 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0444725 |
| RPS6 | ribosomal protein S6 | -0.0416063 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0411375 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0407723 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0395511 |
| MEIS2 | Meis homeobox 2 | -0.0395419 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0387185 |
| RPL35A | ribosomal protein L35a | -0.0383317 |
| SCFD1 | sec1 family domain containing 1 | -0.0382014 |
| CDH19 | cadherin 19, type 2 | -0.0375987 |
| RPL11 | ribosomal protein L11 | -0.0366827 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0364073 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0363198 |
| PCDH7 | protocadherin 7 | -0.0363186 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0357084 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0348593 |
| RASAL2 | RAS protein activator like 2 | -0.0344199 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0342194 |
| HMCN1 | hemicentin 1 | -0.0341184 |
| RPS19 | ribosomal protein S19 | -0.0334325 |
| RPL37A | ribosomal protein L37a | -0.0322908 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0322001 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0321748 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.031864 |
| PRELID2 | PRELI domain containing 2 | -0.0318442 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.031554 |
| SYT1 | synaptotagmin I | -0.0315328 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0307203 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0306162 |
| LRRC4C | leucine rich repeat containing 4C | -0.0299804 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0294793 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0290606 |
| RPL31 | ribosomal protein L31 | -0.0290267 |
| GNAS | GNAS complex locus | -0.0290201 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.028793 |
| WWC2 | WW and C2 domain containing 2 | -0.0284789 |
| DMD | dystrophin | -0.0283697 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0281839 |
| RPS25 | ribosomal protein S25 | -0.027954 |
| RPS8 | ribosomal protein S8 | -0.0278939 |
| NCAM2 | neural cell adhesion molecule 2 | -0.027688 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0270028 |
| RPS2 | ribosomal protein S2 | -0.0269099 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0266164 |
| MAP4 | microtubule-associated protein 4 | -0.0265457 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0264843 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0263882 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0263464 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.026328 |
| RPS27 | ribosomal protein S27 | -0.0262899 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0262424 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0259904 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0254431 |
| SQSTM1 | sequestosome 1 | -0.0253879 |
| UTRN | utrophin | -0.0246589 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0244137 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0243729 |
| RPLP0 | ribosomal protein, large, P0 | -0.0240513 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0239765 |
| CCDC102B | coiled-coil domain containing 102B | -0.0238679 |
| RPL27 | ribosomal protein L27 | -0.0237685 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0237426 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0231977 |
| RPS23 | ribosomal protein S23 | -0.0227121 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0225268 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0225046 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0219333 |
| TRIM2 | tripartite motif containing 2 | -0.021921 |
| SMYD3 | SET and MYND domain containing 3 | -0.0218081 |
| KIAA1328 | KIAA1328 | -0.0216574 |
| RPL23 | ribosomal protein L23 | -0.021646 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0216063 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0216005 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0215369 |
| PRTG | protogenin | -0.0214732 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0214493 |
| MORF4L2 | mortality factor 4 like 2 | -0.0210666 |
| DOK6 | docking protein 6 | -0.0209019 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.020887 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0207633 |
