| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.248819 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.192456 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.12473 |
| TMEM41B | transmembrane protein 41B | 0.0794582 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0792935 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0783929 |
| ACTN4 | actinin, alpha 4 | 0.0736849 |
| RTN4 | reticulon 4 | 0.0719049 |
| JMJD1C | jumonji domain containing 1C | 0.0710839 |
| VIM | vimentin | 0.0677073 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0648447 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0646792 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0580347 |
| VMP1 | vacuole membrane protein 1 | 0.0559864 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0540203 |
| ARRDC3 | arrestin domain containing 3 | 0.0539674 |
| CDK19 | cyclin-dependent kinase 19 | 0.0520748 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0475056 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0446941 |
| TXNRD1 | thioredoxin reductase 1 | 0.0433158 |
| UBC | ubiquitin C | 0.0431093 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.042154 |
| MCL1 | myeloid cell leukemia 1 | 0.0417221 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0416651 |
| SFTPA2 | surfactant protein A2 | 0.041583 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0408474 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0404559 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0399124 |
| FOSL1 | FOS-like antigen 1 | 0.0397944 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0388192 |
| ZFP36 | ZFP36 ring finger protein | 0.0378082 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0372317 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0368738 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0365847 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0365401 |
| OGA | O-GlcNAcase | 0.0345869 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0341666 |
| ZNF292 | zinc finger protein 292 | 0.0338179 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0326378 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0321249 |
| KLF6 | Kruppel-like factor 6 | 0.0315786 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0307513 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0296041 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.029371 |
| GOLGA4 | golgin A4 | 0.0292059 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0291503 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.029008 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0288398 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0281371 |
| MSN | moesin | 0.0279657 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0277984 |
| WASF2 | WAS protein family, member 2 | 0.0275758 |
| ATP13A3 | ATPase type 13A3 | 0.0274541 |
| NUP58 | nucleoporin 58 | 0.0271411 |
| S100A6 | S100 calcium binding protein A6 | 0.0271153 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0269055 |
| ITGAV | integrin, alpha V | 0.0267299 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0267122 |
| FDPS | farnesyl diphosphate synthase | 0.0264672 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0259384 |
| SETD5 | SET domain containing 5 | 0.0257266 |
| SNX14 | sorting nexin 14 | 0.0256242 |
| CALU | calumenin | 0.0255691 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0249204 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0247501 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0242503 |
| ZNF146 | zinc finger protein 146 | 0.0236509 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0234562 |
| THOC2 | THO complex 2 | 0.0234293 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0234052 |
| SESN2 | sestrin 2 | 0.0233557 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0231728 |
| FBL | fibrillarin | 0.022935 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0228497 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0228377 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0227832 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0225716 |
| SUCO | SUN domain containing ossification factor | 0.0225004 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0224273 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0223768 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0223712 |
| SPAG9 | sperm associated antigen 9 | 0.0221854 |
| GOLT1A | golgi transport 1A | 0.0221723 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0220579 |
| FOXO3 | forkhead box O3 | 0.0216785 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0215158 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0213209 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0208915 |
| ANLN | anillin, actin binding protein | 0.0208579 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0208557 |
| FHL2 | four and a half LIM domains 2 | 0.0204758 |
| MKI67 | marker of proliferation Ki-67 | 0.0202934 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0202854 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.020067 |
| PTEN | phosphatase and tensin homolog | 0.0199561 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.019953 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0197667 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0197561 |
| TXNDC12 | thioredoxin domain containing 12 (endoplasmic reticulum) | 0.0197275 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0196213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.159661 |
| AHNAK | AHNAK nucleoprotein | -0.135624 |
| RPS16 | ribosomal protein S16 | -0.117339 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.112319 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.087023 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0684399 |
| RPL35A | ribosomal protein L35a | -0.065071 |
| TMSB10 | thymosin beta 10 | -0.0649798 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.060658 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0600166 |
| VCL | vinculin | -0.058663 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0533508 |
| PTK2 | protein tyrosine kinase 2 | -0.0528146 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0525039 |
| HMGA2 | high mobility group AT-hook 2 | -0.0509692 |
| RPLP2 | ribosomal protein, large, P2 | -0.0493445 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0480053 |
| RPS24 | ribosomal protein S24 | -0.046144 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0453081 |
| INTS6 | integrator complex subunit 6 | -0.0441494 |
| RPLP1 | ribosomal protein, large, P1 | -0.0440159 |
| TNS3 | tensin 3 | -0.0439343 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0427795 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0427515 |
| DST | dystonin | -0.0427248 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0425354 |
| MYOF | myoferlin | -0.0413416 |
| RPS8 | ribosomal protein S8 | -0.0388243 |
| DIAPH2 | diaphanous-related formin 2 | -0.0387631 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0374111 |
| NAV2 | neuron navigator 2 | -0.0373072 |
| EXOC4 | exocyst complex component 4 | -0.0372908 |
| RNF220 | ring finger protein 220 | -0.0358495 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0356031 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0355592 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0351941 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0347494 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.034706 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0340004 |
| PKM | pyruvate kinase, muscle | -0.0330177 |
| ATG7 | autophagy related 7 | -0.0322042 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0319389 |
| CUX1 | cut-like homeobox 1 | -0.0310493 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0307748 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0304893 |
| CTBP2 | C-terminal binding protein 2 | -0.0299872 |
| HMGB1 | high mobility group box 1 | -0.0298294 |
| RPL38 | ribosomal protein L38 | -0.0296176 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0291408 |
| RASAL2 | RAS protein activator like 2 | -0.0291021 |
| MT2A | metallothionein 2A | -0.0289833 |
| RAD51B | RAD51 paralog B | -0.0288384 |
| ZNF407 | zinc finger protein 407 | -0.0281799 |
| TPM1 | tropomyosin 1 (alpha) | -0.027996 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0279548 |
| KRT8 | keratin 8, type II | -0.0278854 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0271081 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0267899 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0267372 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0265021 |
| NEK10 | NIMA-related kinase 10 | -0.0262369 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0258626 |
| ENO1 | enolase 1, (alpha) | -0.0255881 |
| MYO10 | myosin X | -0.0254745 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0254146 |
| CTSD | cathepsin D | -0.025297 |
| PRSS23 | protease, serine, 23 | -0.0252809 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0252605 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0252601 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0252285 |
| EHBP1 | EH domain binding protein 1 | -0.0248924 |
| EGFR | epidermal growth factor receptor | -0.0247677 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0244865 |
| PRKCA | protein kinase C, alpha | -0.0242344 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0237328 |
| RPS27A | ribosomal protein S27a | -0.0236923 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0234347 |
| RPL37A | ribosomal protein L37a | -0.0233047 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0228182 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0227859 |
| RIGI | RNA sensor RIG-I | -0.0226537 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0224187 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.022417 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0223772 |
| NHSL1 | NHS-like 1 | -0.0219706 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0219567 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0219419 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0219389 |
| KRT18 | keratin 18, type I | -0.0218473 |
| FUS | FUS RNA binding protein | -0.0218453 |
| CCND1 | cyclin D1 | -0.0216861 |
| RPL4 | ribosomal protein L4 | -0.0214353 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0212152 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.020986 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0209233 |
| RPS20 | ribosomal protein S20 | -0.020689 |
| GLIS3 | GLIS family zinc finger 3 | -0.0206398 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0205161 |
| COMMD10 | COMM domain containing 10 | -0.0204217 |
| POTEF | POTE ankyrin domain family, member F | -0.0200837 |
