| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.264924 |
| MYO6 | myosin VI | 0.124757 |
| LMO7 | LIM domain 7 | 0.0879655 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.087492 |
| LAMC2 | laminin, gamma 2 | 0.0833525 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0759656 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0754996 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0729007 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0726008 |
| SMAD3 | SMAD family member 3 | 0.0714416 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0701032 |
| EMP1 | epithelial membrane protein 1 | 0.0699062 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0694485 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0689344 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0664718 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0636863 |
| KRT17 | keratin 17, type I | 0.0624657 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.06214 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0613247 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0611657 |
| TMSB4X | thymosin beta 4, X-linked | 0.0600927 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0598784 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0591354 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.059106 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0566206 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0558787 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0550698 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0550682 |
| JMJD1C | jumonji domain containing 1C | 0.0530306 |
| ERBIN | erbb2 interacting protein | 0.052611 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0518614 |
| EGFR | epidermal growth factor receptor | 0.0514896 |
| AFDN | afadin, adherens junction formation factor | 0.0514345 |
| RUNX1 | runt-related transcription factor 1 | 0.0504698 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0499634 |
| EZR | ezrin | 0.0499519 |
| INHBA | inhibin, beta A | 0.0497708 |
| KRT8 | keratin 8, type II | 0.0495832 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0492177 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0484601 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0476101 |
| KRT7 | keratin 7, type II | 0.0475935 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.046758 |
| MYO5B | myosin VB | 0.0452686 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0452483 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0440118 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.043595 |
| RASAL2 | RAS protein activator like 2 | 0.0430623 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0428681 |
| DSG2 | desmoglein 2 | 0.0426459 |
| ANXA2 | annexin A2 | 0.0424573 |
| ACTN4 | actinin, alpha 4 | 0.0422476 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0420759 |
| UBC | ubiquitin C | 0.0418753 |
| GOLGA4 | golgin A4 | 0.0418305 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.041766 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.041614 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0415393 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0407045 |
| SLTM | SAFB-like, transcription modulator | 0.0403652 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.040309 |
| CLTC | clathrin, heavy chain (Hc) | 0.0398116 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0389753 |
| MYO1E | myosin IE | 0.0388502 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0382784 |
| LAMA4 | laminin, alpha 4 | 0.0382746 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0380513 |
| MUC4 | mucin 4, cell surface associated | 0.0376267 |
| WWC1 | WW and C2 domain containing 1 | 0.0372014 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0371989 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0371085 |
| BRD2 | bromodomain containing 2 | 0.0371055 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370477 |
| CALR | calreticulin | 0.0370035 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0367344 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0362475 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0362342 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0360832 |
| FRMD6 | FERM domain containing 6 | 0.0355485 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0353044 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0351289 |
| FNDC3B | fibronectin type III domain containing 3B | 0.034904 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0341675 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0340795 |
| HDAC9 | histone deacetylase 9 | 0.0340642 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.03406 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0340468 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0336865 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0336335 |
| WAC | WW domain containing adaptor with coiled-coil | 0.033386 |
| MYOF | myoferlin | 0.0331213 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0330735 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0327831 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.03261 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0325598 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0320422 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0319527 |
| BCL2L1 | BCL2-like 1 | 0.031902 |
| VMP1 | vacuole membrane protein 1 | 0.0318433 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0316912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157197 |
| RPL35A | ribosomal protein L35a | -0.0713435 |
| NDRG1 | N-myc downstream regulated 1 | -0.0619203 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0582025 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0578489 |
| POTEF | POTE ankyrin domain family, member F | -0.0561179 |
| FTL | ferritin, light polypeptide | -0.0504741 |
| FOSL1 | FOS-like antigen 1 | -0.0490739 |
| TMSB10 | thymosin beta 10 | -0.0462238 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0404808 |
| EGR1 | early growth response 1 | -0.0386596 |
| RPLP1 | ribosomal protein, large, P1 | -0.0358579 |
| HMGA1 | high mobility group AT-hook 1 | -0.0357499 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0348228 |
| RPS6 | ribosomal protein S6 | -0.0319104 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0318491 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.030957 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0293743 |
| TMEM123 | transmembrane protein 123 | -0.029349 |
| KRT19 | keratin 19, type I | -0.0287495 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0286228 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0276846 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025397 |
| PTMA | prothymosin, alpha | -0.0250069 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0248896 |
| HMGB1 | high mobility group box 1 | -0.0239117 |
| TPM4 | tropomyosin 4 | -0.0238054 |
| CENPF | centromere protein F, 350/400kDa | -0.0235009 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0211375 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0207308 |
| RPL23 | ribosomal protein L23 | -0.0204235 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0200816 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0200405 |
| RPS19 | ribosomal protein S19 | -0.0193514 |
| ENO1 | enolase 1, (alpha) | -0.0193035 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.019189 |
| YBX1 | Y box binding protein 1 | -0.0188145 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0185834 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0184348 |
| MX1 | MX dynamin-like GTPase 1 | -0.0183797 |
| S100A11 | S100 calcium binding protein A11 | -0.017901 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0178324 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0175486 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.017525 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0174262 |
| IFI44 | interferon-induced protein 44 | -0.0171919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0169459 |
| ATN1 | atrophin 1 | -0.0167615 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0167361 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0165731 |
| CD44 | CD44 molecule (Indian blood group) | -0.0163952 |
| IFI44L | interferon-induced protein 44-like | -0.015873 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0157618 |
| PFN1 | profilin 1 | -0.0155548 |
| HLA-A | major histocompatibility complex, class I, A | -0.0155355 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0154995 |
| RPL35 | ribosomal protein L35 | -0.0153074 |
| RPS17 | ribosomal protein S17 | -0.0153013 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0151972 |
| PRELID2 | PRELI domain containing 2 | -0.0151869 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0151079 |
| PDE8A | phosphodiesterase 8A | -0.0150764 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0149715 |
| PCBP2 | poly(rC) binding protein 2 | -0.0148898 |
| VIM | vimentin | -0.0147454 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0146094 |
| PKM | pyruvate kinase, muscle | -0.0145518 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0144796 |
| RPS14 | ribosomal protein S14 | -0.0144629 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0143731 |
| RPL34 | ribosomal protein L34 | -0.0141522 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.013974 |
| MX2 | MX dynamin-like GTPase 2 | -0.0139553 |
| BCL9L | B-cell CLL/lymphoma 9-like | -0.0137592 |
| TFG | TRK-fused gene | -0.0136624 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0134866 |
| RPL38 | ribosomal protein L38 | -0.0132516 |
| TAPBP | TAP binding protein (tapasin) | -0.0131577 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0129717 |
| TSC22D2 | TSC22 domain family, member 2 | -0.012925 |
| RPS8 | ribosomal protein S8 | -0.0128235 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0127005 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.0126991 |
| RPS15 | ribosomal protein S15 | -0.012673 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0125628 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0124554 |
| RPLP2 | ribosomal protein, large, P2 | -0.0124312 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.01241 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0123667 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0123167 |
| ADM | adrenomedullin | -0.0122016 |
| PERP | PERP, TP53 apoptosis effector | -0.0121482 |
| RPL36 | ribosomal protein L36 | -0.0120776 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0120634 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.012025 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.0119542 |
| SQSTM1 | sequestosome 1 | -0.0118858 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0117747 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0117221 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0115311 |
