| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.27861 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.111264 |
| MCL1 | myeloid cell leukemia 1 | 0.109081 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0860293 |
| JMJD1C | jumonji domain containing 1C | 0.0836046 |
| HDAC9 | histone deacetylase 9 | 0.0827117 |
| LAMB3 | laminin, beta 3 | 0.0705316 |
| NUP58 | nucleoporin 58 | 0.0682837 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.065094 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0612403 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0606994 |
| PTK2 | protein tyrosine kinase 2 | 0.0603154 |
| GOLGA4 | golgin A4 | 0.0595506 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0590851 |
| RPS6 | ribosomal protein S6 | 0.0588087 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0575684 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0560208 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0552409 |
| RTN4 | reticulon 4 | 0.0539623 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0529722 |
| CAPRIN2 | caprin family member 2 | 0.0524965 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0522222 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0509821 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0507093 |
| USP34 | ubiquitin specific peptidase 34 | 0.0498778 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0488368 |
| DGKI | diacylglycerol kinase, iota | 0.0478918 |
| SETD5 | SET domain containing 5 | 0.0470159 |
| RPL7 | ribosomal protein L7 | 0.0469127 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0449353 |
| RPL3 | ribosomal protein L3 | 0.0443852 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0442849 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0441895 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0441433 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0436619 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0436196 |
| WDR26 | WD repeat domain 26 | 0.0424114 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0420753 |
| GOLGA2 | golgin A2 | 0.0417204 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0415544 |
| PGK1 | phosphoglycerate kinase 1 | 0.0413511 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0405419 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0400929 |
| PRRC2C | proline-rich coiled-coil 2C | 0.040011 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0399223 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0398439 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0397675 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.039551 |
| LDHA | lactate dehydrogenase A | 0.0393293 |
| SBF2 | SET binding factor 2 | 0.0390675 |
| WDR43 | WD repeat domain 43 | 0.0388977 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0386049 |
| SET | SET nuclear proto-oncogene | 0.0384096 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0375944 |
| ANO6 | anoctamin 6 | 0.0375632 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0371935 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0371885 |
| SRPK2 | SRSF protein kinase 2 | 0.0371687 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0369165 |
| NDRG1 | N-myc downstream regulated 1 | 0.0368534 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0363346 |
| IL6ST | interleukin 6 signal transducer | 0.0353758 |
| ABI1 | abl-interactor 1 | 0.0350084 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0345066 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0345 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0343576 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0342518 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0341408 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0337331 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.032949 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0327442 |
| PCBP2 | poly(rC) binding protein 2 | 0.0321405 |
| CALU | calumenin | 0.0318892 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0315191 |
| HMGA1 | high mobility group AT-hook 1 | 0.0313179 |
| ERBIN | erbb2 interacting protein | 0.0311833 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0310841 |
| CORO1C | coronin, actin binding protein, 1C | 0.0309745 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0306439 |
| USP24 | ubiquitin specific peptidase 24 | 0.0301809 |
| ACTG1 | actin gamma 1 | 0.0300304 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.0298216 |
| CRY1 | cryptochrome circadian clock 1 | 0.0298042 |
| TMF1 | TATA element modulatory factor 1 | 0.0295483 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0290111 |
| BRD2 | bromodomain containing 2 | 0.0290053 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0289532 |
| FAM120A | family with sequence similarity 120A | 0.0289288 |
| NAV3 | neuron navigator 3 | 0.0287877 |
| NF1 | neurofibromin 1 | 0.028664 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0285843 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0285113 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0283538 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0283047 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0282391 |
| COPA | coatomer protein complex, subunit alpha | 0.0281188 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0280332 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.02797 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0278145 |
| OGA | O-GlcNAcase | 0.027471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF438 | zinc finger protein 438 | -0.140305 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.120946 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.108192 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0937586 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0874451 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0776227 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0761099 |
| HMGA2 | high mobility group AT-hook 2 | -0.0712552 |
| AHNAK | AHNAK nucleoprotein | -0.0685452 |
| TTR | transthyretin | -0.0679156 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0604783 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0571573 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0548637 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0528365 |
| MTAP | methylthioadenosine phosphorylase | -0.0513584 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0495706 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0466552 |
| BNC2 | basonuclin 2 | -0.0448191 |
| TCF12 | transcription factor 12 | -0.0447351 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0439434 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0433068 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0410305 |
| MTDH | metadherin | -0.0376061 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0371801 |
| SP100 | SP100 nuclear antigen | -0.0371162 |
| RPS24 | ribosomal protein S24 | -0.0365733 |
| GPHN | gephyrin | -0.0363969 |
| RIGI | RNA sensor RIG-I | -0.035673 |
| RPL35A | ribosomal protein L35a | -0.0356582 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0348348 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347766 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.034705 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0338564 |
| ANXA2 | annexin A2 | -0.0337505 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.033307 |
| RPS27A | ribosomal protein S27a | -0.0324599 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0313677 |
| TUBB4B | tubulin, beta 4B class IVb | -0.031346 |
| TMSB10 | thymosin beta 10 | -0.031216 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0305373 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0298815 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0296675 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0292644 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0290213 |
| MX2 | MX dynamin-like GTPase 2 | -0.0289942 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0287761 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0286106 |
| NFIA | nuclear factor I/A | -0.0285814 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0279132 |
| RPL4 | ribosomal protein L4 | -0.0277375 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0277242 |
| MX1 | MX dynamin-like GTPase 1 | -0.0276155 |
| FRMD6 | FERM domain containing 6 | -0.0274842 |
| RPL38 | ribosomal protein L38 | -0.0271831 |
| UBB | ubiquitin B | -0.0270018 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0269781 |
| EXOC4 | exocyst complex component 4 | -0.0265862 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0263339 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0260998 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0258781 |
| CD44 | CD44 molecule (Indian blood group) | -0.0258568 |
| RPL23 | ribosomal protein L23 | -0.0256517 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0255123 |
| CDK6 | cyclin-dependent kinase 6 | -0.0253854 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0253239 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0253027 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0246866 |
| HMGB1 | high mobility group box 1 | -0.0244741 |
| MCM4 | minichromosome maintenance complex component 4 | -0.024312 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.02422 |
| TRIM56 | tripartite motif containing 56 | -0.024165 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.024159 |
| CAST | calpastatin | -0.0241563 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0238146 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0237264 |
| TASP1 | taspase, threonine aspartase, 1 | -0.0236862 |
| ANTXR2 | anthrax toxin receptor 2 | -0.02364 |
| PRKCE | protein kinase C, epsilon | -0.0233056 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0232836 |
| FOXP1 | forkhead box P1 | -0.0231182 |
| PROCR | protein C receptor, endothelial | -0.0230913 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0230658 |
| GNAS | GNAS complex locus | -0.0228128 |
| S100A2 | S100 calcium binding protein A2 | -0.0223664 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0221159 |
| RPL35 | ribosomal protein L35 | -0.0221037 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0218478 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0218409 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0214183 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0210894 |
| NUP214 | nucleoporin 214kDa | -0.0210598 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0209722 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0208035 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.020786 |
| TUBA1B | tubulin, alpha 1b | -0.0205704 |
| FRMD5 | FERM domain containing 5 | -0.0205503 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0203541 |
| G0S2 | G0/G1 switch 2 | -0.0203505 |
| SUMF1 | sulfatase modifying factor 1 | -0.0203352 |
| ZFHX3 | zinc finger homeobox 3 | -0.0203141 |
