| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Atazanavir (sulfate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.376676 |
| STC1 | stanniocalcin 1 | 0.112699 |
| PGK1 | phosphoglycerate kinase 1 | 0.0938277 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0821113 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0637384 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.060889 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0607557 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0603674 |
| ASPH | aspartate beta-hydroxylase | 0.0597505 |
| GOLGA4 | golgin A4 | 0.0588882 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.05677 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.05602 |
| FAM20C | family with sequence similarity 20, member C | 0.0555468 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.053486 |
| FNDC3B | fibronectin type III domain containing 3B | 0.052934 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0522696 |
| NAV2 | neuron navigator 2 | 0.0512273 |
| ATP13A3 | ATPase type 13A3 | 0.0510486 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0504743 |
| AFAP1 | actin filament associated protein 1 | 0.0491911 |
| NDRG1 | N-myc downstream regulated 1 | 0.0491669 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0474519 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0443835 |
| COL1A2 | collagen, type I, alpha 2 | 0.0433465 |
| FLNB | filamin B, beta | 0.0432371 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0427509 |
| CD44 | CD44 molecule (Indian blood group) | 0.0420466 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0418497 |
| ZNF292 | zinc finger protein 292 | 0.041525 |
| CALU | calumenin | 0.040889 |
| MSN | moesin | 0.039989 |
| YEATS2 | YEATS domain containing 2 | 0.0393125 |
| FMNL2 | formin-like 2 | 0.0390574 |
| SETD5 | SET domain containing 5 | 0.038916 |
| MKI67 | marker of proliferation Ki-67 | 0.0388087 |
| NBAS | neuroblastoma amplified sequence | 0.0383639 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0380219 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0380209 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0379051 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0374093 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0363802 |
| FRMD4A | FERM domain containing 4A | 0.0358329 |
| MMP12 | matrix metallopeptidase 12 | 0.0358089 |
| NF1 | neurofibromin 1 | 0.0357964 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0352915 |
| SBF2 | SET binding factor 2 | 0.0348363 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0344803 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.033966 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0339253 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.033868 |
| HM13 | histocompatibility (minor) 13 | 0.0332065 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0314075 |
| COPA | coatomer protein complex, subunit alpha | 0.031151 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0310926 |
| NRP1 | neuropilin 1 | 0.0308603 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0301111 |
| TMF1 | TATA element modulatory factor 1 | 0.0297299 |
| CLTC | clathrin, heavy chain (Hc) | 0.0291578 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0289886 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0286974 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0285917 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0284843 |
| HMGA2 | high mobility group AT-hook 2 | 0.0282817 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0281362 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0280508 |
| OGA | O-GlcNAcase | 0.0277863 |
| MTSS1 | metastasis suppressor 1 | 0.0274583 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0274021 |
| AFDN | afadin, adherens junction formation factor | 0.0272883 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0272322 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0272014 |
| INHBA | inhibin, beta A | 0.0271069 |
| MYO1B | myosin IB | 0.026955 |
| AHNAK | AHNAK nucleoprotein | 0.0269045 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0266107 |
| FNIP1 | folliculin interacting protein 1 | 0.0265366 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0264649 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0263109 |
| NUP58 | nucleoporin 58 | 0.0262971 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.026289 |
| PTK2 | protein tyrosine kinase 2 | 0.0262875 |
| DIAPH3 | diaphanous-related formin 3 | 0.0262458 |
| IL1B | interleukin 1, beta | 0.0262138 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0260494 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.025468 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0252588 |
| NKTR | natural killer cell triggering receptor | 0.0252348 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0252194 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0251087 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0243759 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0242736 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0242663 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0242189 |
| TMEM39A | transmembrane protein 39A | 0.0239701 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0238765 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.023817 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0237789 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0236743 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0236265 |
| COL5A1 | collagen, type V, alpha 1 | 0.0233851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130246 |
| FTL | ferritin, light polypeptide | -0.0836846 |
| EGR1 | early growth response 1 | -0.0790629 |
| POTEF | POTE ankyrin domain family, member F | -0.0629053 |
| VIM | vimentin | -0.0561056 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0482837 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0472018 |
| RPLP1 | ribosomal protein, large, P1 | -0.0450122 |
| TMSB10 | thymosin beta 10 | -0.0391984 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0362007 |
| IER3 | immediate early response 3 | -0.0355824 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0352209 |
| CDH13 | cadherin 13 | -0.0332145 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0313164 |
| JUN | jun proto-oncogene | -0.0309627 |
| ANXA2 | annexin A2 | -0.0290177 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0287347 |
| RPS19 | ribosomal protein S19 | -0.0279241 |
| YBX1 | Y box binding protein 1 | -0.027549 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0271946 |
| HLA-B | major histocompatibility complex, class I, B | -0.0270493 |
| RPS8 | ribosomal protein S8 | -0.0261583 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0258513 |
| RYBP | RING1 and YY1 binding protein | -0.0255745 |
| RPL28 | ribosomal protein L28 | -0.0255445 |
| RPL31 | ribosomal protein L31 | -0.0254368 |
| RPL35A | ribosomal protein L35a | -0.0246303 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.024331 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0240905 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0238514 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235495 |
| PFN1 | profilin 1 | -0.0229623 |
| RPL23 | ribosomal protein L23 | -0.0228198 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0225943 |
| RPS6 | ribosomal protein S6 | -0.0218241 |
| PKM | pyruvate kinase, muscle | -0.0216807 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0215634 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.021427 |
| SP100 | SP100 nuclear antigen | -0.0212532 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0211942 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.021063 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0206899 |
| RPS12 | ribosomal protein S12 | -0.0200391 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0197795 |
| RPL8 | ribosomal protein L8 | -0.0196353 |
| CST3 | cystatin C | -0.0196059 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0194306 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0192029 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0189726 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.018962 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0188503 |
| HMGB1 | high mobility group box 1 | -0.0188472 |
| CADM1 | cell adhesion molecule 1 | -0.018844 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0187226 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0186632 |
| RPS5 | ribosomal protein S5 | -0.0185957 |
| RPLP2 | ribosomal protein, large, P2 | -0.018551 |
| IER2 | immediate early response 2 | -0.0185192 |
| SHISA5 | shisa family member 5 | -0.0183843 |
| ADM | adrenomedullin | -0.0181431 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0181171 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0178878 |
| LRRC23 | leucine rich repeat containing 23 | -0.0178236 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0177905 |
| RPL36 | ribosomal protein L36 | -0.0177628 |
| RPS16 | ribosomal protein S16 | -0.0177526 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0173349 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0171266 |
| TEX14 | testis expressed 14 | -0.0170581 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0170167 |
| CDA | cytidine deaminase | -0.0170135 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.016567 |
| BSG | basigin (Ok blood group) | -0.016534 |
| S100A10 | S100 calcium binding protein A10 | -0.0165079 |
| TKT | transketolase | -0.0164829 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0164828 |
| MYOF | myoferlin | -0.0164492 |
| LIMA1 | LIM domain and actin binding 1 | -0.0164382 |
| HLA-A | major histocompatibility complex, class I, A | -0.0163594 |
| MMP2 | matrix metallopeptidase 2 | -0.0162123 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0161864 |
| RPL32 | ribosomal protein L32 | -0.0161665 |
| FAM162A | family with sequence similarity 162, member A | -0.016025 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0159841 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0159302 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.015858 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0158136 |
| NABP1 | nucleic acid binding protein 1 | -0.0155634 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0154612 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0151414 |
| RPS20 | ribosomal protein S20 | -0.0150263 |
| RPS4X | ribosomal protein S4, X-linked | -0.0150006 |
| TGFB1 | transforming growth factor, beta 1 | -0.0148833 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0148806 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0147063 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0146482 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0144868 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0142662 |
| HMGA1 | high mobility group AT-hook 1 | -0.0140781 |
| IRF1 | interferon regulatory factor 1 | -0.0139567 |
