| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.144263 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.136502 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.112166 |
| GPC6 | glypican 6 | 0.108059 |
| STC1 | stanniocalcin 1 | 0.102796 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.101751 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0974002 |
| NDRG1 | N-myc downstream regulated 1 | 0.0880509 |
| ENO1 | enolase 1, (alpha) | 0.0869159 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0855491 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0823391 |
| RORA | RAR-related orphan receptor A | 0.0792393 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0737256 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0737034 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0720265 |
| VGF | VGF nerve growth factor inducible | 0.0697426 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.064 |
| ESRRG | estrogen-related receptor gamma | 0.0581799 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0541222 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0538443 |
| CHGB | chromogranin B | 0.0519347 |
| DTNA | dystrobrevin, alpha | 0.051882 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0503685 |
| CPE | carboxypeptidase E | 0.050334 |
| NRG1 | neuregulin 1 | 0.0488661 |
| PCBP3 | poly(rC) binding protein 3 | 0.0484586 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0478193 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0476302 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0475279 |
| SNTG1 | syntrophin, gamma 1 | 0.0470225 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.045385 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0453318 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.044578 |
| PGK1 | phosphoglycerate kinase 1 | 0.044349 |
| PTMA | prothymosin, alpha | 0.0442234 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.043443 |
| KIF26B | kinesin family member 26B | 0.0433263 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0432531 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0431922 |
| MAP1B | microtubule-associated protein 1B | 0.0429151 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0427503 |
| RPS3 | ribosomal protein S3 | 0.0426218 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0423997 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0413104 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0412413 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0411803 |
| INHBA | inhibin, beta A | 0.0406936 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.040287 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0395895 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0390434 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0388329 |
| KLHL29 | kelch-like family member 29 | 0.0383116 |
| PTCHD4 | patched domain containing 4 | 0.0379849 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0379826 |
| MED13L | mediator complex subunit 13-like | 0.0369211 |
| APP | amyloid beta (A4) precursor protein | 0.0363102 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0360524 |
| SMYD3 | SET and MYND domain containing 3 | 0.0360462 |
| ACTG1 | actin gamma 1 | 0.0359036 |
| CALCA | calcitonin-related polypeptide alpha | 0.0347945 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.034711 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0346898 |
| ZFHX3 | zinc finger homeobox 3 | 0.0344982 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.033986 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0338679 |
| NAV1 | neuron navigator 1 | 0.0337317 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0332966 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0330997 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0330717 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0326902 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0322375 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321532 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.032011 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.031753 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314697 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.031423 |
| PKM | pyruvate kinase, muscle | 0.0313742 |
| COPA | coatomer protein complex, subunit alpha | 0.031257 |
| NELL1 | NEL-like 1 (chicken) | 0.030955 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.030829 |
| EFNA5 | ephrin-A5 | 0.0304872 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0303201 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0300098 |
| SCG2 | secretogranin II | 0.0297593 |
| MKI67 | marker of proliferation Ki-67 | 0.0289617 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.0288204 |
| FAM13A | family with sequence similarity 13, member A | 0.0287755 |
| TMSB4X | thymosin beta 4, X-linked | 0.0287247 |
| TPD52 | tumor protein D52 | 0.0286333 |
| SVIL | supervillin | 0.0286221 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0283217 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0281474 |
| PAEP | progestagen-associated endometrial protein | 0.0280947 |
| FN1 | fibronectin 1 | 0.0280755 |
| MSN | moesin | 0.0278189 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0276782 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0274491 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0273064 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.027186 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0271792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0770909 |
| TENM1 | teneurin transmembrane protein 1 | -0.0737369 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0518027 |
| CENPF | centromere protein F, 350/400kDa | -0.0358501 |
| TXNRD1 | thioredoxin reductase 1 | -0.0353275 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0336166 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0278583 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.027799 |
| POTEF | POTE ankyrin domain family, member F | -0.0256951 |
| NLGN1 | neuroligin 1 | -0.02512 |
| HMGB1 | high mobility group box 1 | -0.025024 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0246326 |
| SYT1 | synaptotagmin I | -0.0237154 |
| RIT2 | Ras-like without CAAX 2 | -0.0214851 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0212364 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0207343 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0205973 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0203276 |
| TOX | thymocyte selection-associated high mobility group box | -0.0202653 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0202082 |
| MTMR7 | myotubularin related protein 7 | -0.0198836 |
| GPHN | gephyrin | -0.0198516 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0188821 |
| CADM2 | cell adhesion molecule 2 | -0.0188575 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0187012 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0180012 |
| RTN4 | reticulon 4 | -0.0177113 |
| PDE10A | phosphodiesterase 10A | -0.0174921 |
| KIAA0825 | KIAA0825 | -0.0174803 |
| NUP155 | nucleoporin 155kDa | -0.0168282 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0166706 |
| WWOX | WW domain containing oxidoreductase | -0.0161932 |
| RALYL | RALY RNA binding protein-like | -0.0161043 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0160421 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0159067 |
| NYAP2 | neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 | -0.0158045 |
| ZNF804A | zinc finger protein 804A | -0.0155099 |
| FTL | ferritin, light polypeptide | -0.0152606 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | -0.0152486 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0152319 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0150026 |
| KITLG | KIT ligand | -0.0148036 |
| EML6 | echinoderm microtubule associated protein like 6 | -0.014506 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0141759 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0140711 |
| TRIM9 | tripartite motif containing 9 | -0.0140422 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0139142 |
| ADAR | adenosine deaminase, RNA-specific | -0.0138178 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0133867 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0131769 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0130857 |
| TUBB | tubulin, beta class I | -0.0129915 |
| RFX7 | regulatory factor X, 7 | -0.0129394 |
| CBX3 | chromobox homolog 3 | -0.0128563 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0127341 |
| FOXP2 | forkhead box P2 | -0.0127103 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0126031 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0125543 |
| NRXN1 | neurexin 1 | -0.0122922 |
| WDR7 | WD repeat domain 7 | -0.012178 |
| MATR3 | matrin 3 | -0.0121675 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0120363 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0120028 |
| CNBD1 | cyclic nucleotide binding domain containing 1 | -0.0119771 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | -0.0118573 |
| POU6F2 | POU class 6 homeobox 2 | -0.0116727 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0116536 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0115192 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0115134 |
| RPL35A | ribosomal protein L35a | -0.0113552 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0112919 |
| FAM162A | family with sequence similarity 162, member A | -0.0112435 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0110347 |
| KIAA1328 | KIAA1328 | -0.0109959 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.010977 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0107755 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0107485 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.010716 |
| RIGI | RNA sensor RIG-I | -0.0107064 |
| FANCL | Fanconi anemia, complementation group L | -0.0107036 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0106808 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 | -0.0106565 |
| SCFD2 | sec1 family domain containing 2 | -0.0106046 |
| CNTNAP5 | contactin associated protein-like 5 | -0.0105814 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0104542 |
| METAP2 | methionyl aminopeptidase 2 | -0.0104435 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.010438 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0104228 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.010255 |
| PCDH9 | protocadherin 9 | -0.0102361 |
| TMEM117 | transmembrane protein 117 | -0.0102342 |
| ANO10 | anoctamin 10 | -0.0102331 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | -0.0101491 |
| ANK2 | ankyrin 2, neuronal | -0.0101293 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | -0.0101223 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0101023 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0100305 |
| NIN | ninein (GSK3B interacting protein) | -0.00991731 |
| GRM8 | glutamate receptor, metabotropic 8 | -0.00988332 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.00974385 |
