| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.203122 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.110113 |
| NLGN1 | neuroligin 1 | 0.101796 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0972851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0972135 |
| LSAMP | limbic system-associated membrane protein | 0.0921616 |
| GOLGA4 | golgin A4 | 0.0773088 |
| FMNL2 | formin-like 2 | 0.0698693 |
| NRG3 | neuregulin 3 | 0.0696395 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.059868 |
| MSI2 | musashi RNA-binding protein 2 | 0.0551241 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0543769 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0523345 |
| VIM | vimentin | 0.0519883 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.048317 |
| SBF2 | SET binding factor 2 | 0.0460991 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0455972 |
| MSN | moesin | 0.0445027 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0428649 |
| FHIT | fragile histidine triad | 0.0412797 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0409117 |
| FLNB | filamin B, beta | 0.0392815 |
| MCL1 | myeloid cell leukemia 1 | 0.03884 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0374944 |
| MMP12 | matrix metallopeptidase 12 | 0.0373363 |
| SFTPA2 | surfactant protein A2 | 0.0372302 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0365695 |
| KAZN | kazrin, periplakin interacting protein | 0.0364628 |
| YEATS2 | YEATS domain containing 2 | 0.0359743 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0359655 |
| SETD5 | SET domain containing 5 | 0.0359341 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0358566 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0352073 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.034965 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337907 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0335753 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0334564 |
| PRELID2 | PRELI domain containing 2 | 0.033165 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0329937 |
| NOTCH2 | notch 2 | 0.0326872 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0318814 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0318762 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0316163 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0316151 |
| RAD51B | RAD51 paralog B | 0.0315484 |
| BBX | bobby sox homolog (Drosophila) | 0.0310429 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0308351 |
| CTTN | cortactin | 0.0308196 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0306405 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0303201 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.030283 |
| NBAS | neuroblastoma amplified sequence | 0.0299475 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0299468 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0296751 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0294579 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0292702 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.029188 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0288963 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0288605 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0281417 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0280328 |
| NGLY1 | N-glycanase 1 | 0.0275887 |
| USP34 | ubiquitin specific peptidase 34 | 0.0275267 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0275064 |
| TPM3 | tropomyosin 3 | 0.027191 |
| CDK19 | cyclin-dependent kinase 19 | 0.0269741 |
| CADM1 | cell adhesion molecule 1 | 0.0268865 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0268306 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0265387 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0264928 |
| RPL3 | ribosomal protein L3 | 0.025887 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258169 |
| OGA | O-GlcNAcase | 0.025468 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249668 |
| POM121 | POM121 transmembrane nucleoporin | 0.0248662 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0245315 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0245196 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.024096 |
| MKI67 | marker of proliferation Ki-67 | 0.02406 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0240192 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0239716 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.023926 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0236045 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0235061 |
| CLIC4 | chloride intracellular channel 4 | 0.0234785 |
| CALD1 | caldesmon 1 | 0.0233413 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0231297 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230645 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0227856 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0225354 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0225066 |
| AFF1 | AF4/FMR2 family, member 1 | 0.022452 |
| LDHA | lactate dehydrogenase A | 0.0224023 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0223954 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0223837 |
| HELZ | helicase with zinc finger | 0.0223616 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0222121 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0219193 |
| SUCO | SUN domain containing ossification factor | 0.0218852 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0218279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | -0.113572 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.108903 |
| MT2A | metallothionein 2A | -0.0906377 |
| CCND1 | cyclin D1 | -0.0691881 |
| FRMD5 | FERM domain containing 5 | -0.0647558 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0529863 |
| TMSB10 | thymosin beta 10 | -0.0464164 |
| FRMD4A | FERM domain containing 4A | -0.0458002 |
| RPS3 | ribosomal protein S3 | -0.0396856 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0388551 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0371185 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0359504 |
| IER3 | immediate early response 3 | -0.0354148 |
| FTL | ferritin, light polypeptide | -0.0349099 |
| POTEF | POTE ankyrin domain family, member F | -0.0338365 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0332614 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0314176 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0310896 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305082 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0304315 |
| RASAL2 | RAS protein activator like 2 | -0.0301129 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0296501 |
| TP63 | tumor protein p63 | -0.0285733 |
| CDK6 | cyclin-dependent kinase 6 | -0.0279476 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0274975 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0270581 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0257202 |
| RUNX1 | runt-related transcription factor 1 | -0.0256158 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0251504 |
| PLSCR1 | phospholipid scramblase 1 | -0.025062 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0249835 |
| ENO1 | enolase 1, (alpha) | -0.0248609 |
| ANXA2 | annexin A2 | -0.0242592 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0236504 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.022889 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0220146 |
| RPL23 | ribosomal protein L23 | -0.0217642 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0216462 |
| RNF213 | ring finger protein 213 | -0.021633 |
| RPL32 | ribosomal protein L32 | -0.0210813 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.020831 |
| RPL38 | ribosomal protein L38 | -0.0208263 |
| RPL19 | ribosomal protein L19 | -0.0205294 |
| RIGI | RNA sensor RIG-I | -0.0204175 |
| SP100 | SP100 nuclear antigen | -0.0198545 |
| TKT | transketolase | -0.0197794 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0197078 |
| RPS29 | ribosomal protein S29 | -0.0196136 |
| RPL28 | ribosomal protein L28 | -0.0194303 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0193693 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0188162 |
| UBB | ubiquitin B | -0.0186298 |
| TULP4 | tubby like protein 4 | -0.0184271 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0182054 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0178988 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0176638 |
| CA8 | carbonic anhydrase VIII | -0.0174455 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0173705 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0171597 |
| RPL31 | ribosomal protein L31 | -0.0170323 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.017025 |
| RPLP2 | ribosomal protein, large, P2 | -0.0168256 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0167613 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0166993 |
| RPS8 | ribosomal protein S8 | -0.0164781 |
| RPL35A | ribosomal protein L35a | -0.0164619 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0164256 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0164214 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0163365 |
| ZNF608 | zinc finger protein 608 | -0.0161282 |
| RPL27 | ribosomal protein L27 | -0.0160473 |
| TXNRD1 | thioredoxin reductase 1 | -0.0158818 |
| RPS16 | ribosomal protein S16 | -0.0156333 |
| FBXO32 | F-box protein 32 | -0.015603 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0155484 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0153419 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0152464 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0151442 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0151291 |
| BSG | basigin (Ok blood group) | -0.0151277 |
| NIN | ninein (GSK3B interacting protein) | -0.0150467 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.014919 |
| RPL12 | ribosomal protein L12 | -0.0148794 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0145024 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0144955 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0144834 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0143969 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0143687 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0142917 |
| TNPO1 | transportin 1 | -0.0142712 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0141943 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0140798 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0140513 |
| RPL8 | ribosomal protein L8 | -0.0140484 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0140292 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0139909 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0139182 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0138417 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0137955 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0137863 |
