| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.184062 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.159072 |
| VCL | vinculin | 0.152423 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.120615 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.11565 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.11427 |
| PTMA | prothymosin, alpha | 0.109482 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.106627 |
| TJP1 | tight junction protein 1 | 0.101057 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.098668 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0958324 |
| SBF2 | SET binding factor 2 | 0.0903758 |
| FLNB | filamin B, beta | 0.0892044 |
| HDAC9 | histone deacetylase 9 | 0.0863767 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.085333 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0812093 |
| EVI5 | ecotropic viral integration site 5 | 0.0761045 |
| LDHA | lactate dehydrogenase A | 0.0734684 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0711191 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.069372 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0685996 |
| FOXP1 | forkhead box P1 | 0.0658628 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0618518 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0583611 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0576228 |
| LOXL3 | lysyl oxidase-like 3 | 0.0572953 |
| NBEA | neurobeachin | 0.0565513 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0543987 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.05332 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0525872 |
| TMEM65 | transmembrane protein 65 | 0.0525673 |
| NFIA | nuclear factor I/A | 0.0519226 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0517203 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.048835 |
| WDR43 | WD repeat domain 43 | 0.0481964 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0453262 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0451964 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0447016 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0437576 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0433054 |
| S100A6 | S100 calcium binding protein A6 | 0.0427734 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0420695 |
| CENPF | centromere protein F, 350/400kDa | 0.0420667 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0420575 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0416334 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0415243 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0414737 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0413587 |
| PDGFC | platelet derived growth factor C | 0.0407316 |
| RPS6 | ribosomal protein S6 | 0.0402328 |
| NEBL | nebulette | 0.0401817 |
| EFNA5 | ephrin-A5 | 0.040012 |
| SMYD3 | SET and MYND domain containing 3 | 0.0396668 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0391476 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.038857 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0384829 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0383656 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0381898 |
| RPLP0 | ribosomal protein, large, P0 | 0.037828 |
| RHOA | ras homolog family member A | 0.037606 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0372116 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0368752 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0367456 |
| PRPF38B | pre-mRNA processing factor 38B | 0.036617 |
| TXNIP | thioredoxin interacting protein | 0.0362689 |
| NAV2 | neuron navigator 2 | 0.0356926 |
| MKI67 | marker of proliferation Ki-67 | 0.0356426 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0351999 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.03511 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0347693 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0347377 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342987 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.034056 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.033853 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0335176 |
| EGFR | epidermal growth factor receptor | 0.0335149 |
| FNIP1 | folliculin interacting protein 1 | 0.0328761 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0328187 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0324689 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0324269 |
| GSE1 | Gse1 coiled-coil protein | 0.0324188 |
| CDV3 | CDV3 homolog (mouse) | 0.0322515 |
| GOLGA4 | golgin A4 | 0.0321415 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0316643 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0315321 |
| SEPTIN11 | septin 11 | 0.0312314 |
| ANKRD12 | ankyrin repeat domain 12 | 0.031171 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0303226 |
| DIAPH2 | diaphanous-related formin 2 | 0.0302389 |
| FHIT | fragile histidine triad | 0.0299858 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0297443 |
| ACTG1 | actin gamma 1 | 0.0295522 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0294293 |
| GOLGA2 | golgin A2 | 0.0291287 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0291257 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0291031 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0290186 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0288301 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0286239 |
| MYOF | myoferlin | 0.0283311 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.069486 |
| RPS2 | ribosomal protein S2 | -0.0663382 |
| PKM | pyruvate kinase, muscle | -0.0641925 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0596742 |
| AHNAK | AHNAK nucleoprotein | -0.0474746 |
| RPL5 | ribosomal protein L5 | -0.0429958 |
| NCKAP1 | NCK-associated protein 1 | -0.0412625 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0397839 |
| RPS3 | ribosomal protein S3 | -0.0372884 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0351303 |
| RPL38 | ribosomal protein L38 | -0.0309919 |
| TXNRD1 | thioredoxin reductase 1 | -0.0305116 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0300373 |
| RLF | rearranged L-myc fusion | -0.0284596 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0284494 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0282926 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0276675 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0265296 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0260928 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0258611 |
| KIAA2026 | KIAA2026 | -0.0253552 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0251844 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0250551 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.024984 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0248938 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0248616 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0246699 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0243138 |
| TFG | TRK-fused gene | -0.0242828 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0237162 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0236145 |
| RPL12 | ribosomal protein L12 | -0.0227747 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0225341 |
| HBS1L | HBS1-like translational GTPase | -0.0223535 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0221333 |
| MACROD2 | MACRO domain containing 2 | -0.0220343 |
| RPS18 | ribosomal protein S18 | -0.0215735 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0215681 |
| CDC73 | cell division cycle 73 | -0.0214864 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0211626 |
| MATR3 | matrin 3 | -0.0211554 |
| MEF2A | myocyte enhancer factor 2A | -0.0208405 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.020794 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0207658 |
| PHIP | pleckstrin homology domain interacting protein | -0.0203971 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0202043 |
| OGA | O-GlcNAcase | -0.0200851 |
| MALT1 | MALT1 paracaspase | -0.0200753 |
| RPS12 | ribosomal protein S12 | -0.0200291 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0197779 |
| RPS13 | ribosomal protein S13 | -0.0196335 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.019622 |
| MED13L | mediator complex subunit 13-like | -0.0195559 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0195533 |
| SRP54 | signal recognition particle 54kDa | -0.0195285 |
| HDAC3 | histone deacetylase 3 | -0.019514 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0194427 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0194222 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0194147 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0194026 |
| RACK1 | receptor for activated C kinase 1 | -0.0190254 |
| CORO1C | coronin, actin binding protein, 1C | -0.0190248 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0190025 |
| RNF24 | ring finger protein 24 | -0.0188943 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0187915 |
| NOP58 | NOP58 ribonucleoprotein | -0.0187044 |
| H1-4 | H1.4 linker histone, cluster member | -0.0186195 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0184968 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0184759 |
| RPL28 | ribosomal protein L28 | -0.0183343 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0180433 |
| RYBP | RING1 and YY1 binding protein | -0.0179653 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0177681 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0177229 |
| SERINC1 | serine incorporator 1 | -0.0177038 |
| GLI2 | GLI family zinc finger 2 | -0.0175944 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0173158 |
| TAOK1 | TAO kinase 1 | -0.0171299 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.0169618 |
| FBXO11 | F-box protein 11 | -0.0168548 |
| HBP1 | HMG-box transcription factor 1 | -0.0167904 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0167418 |
| TLK1 | tousled-like kinase 1 | -0.0166624 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0165327 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0163893 |
| POTEF | POTE ankyrin domain family, member F | -0.0163376 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0163358 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0162105 |
| S100A9 | S100 calcium binding protein A9 | -0.0161891 |
| HMBOX1 | homeobox containing 1 | -0.0161407 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0161316 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0161113 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -0.0160908 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0160727 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0160553 |
| RBM39 | RNA binding motif protein 39 | -0.0159381 |
| TMEM59 | transmembrane protein 59 | -0.015932 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0158458 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0157243 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0156662 |
