| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.134987 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0895703 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0874163 |
| GOLGA4 | golgin A4 | 0.0874002 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0806913 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0760545 |
| MCL1 | myeloid cell leukemia 1 | 0.0760307 |
| FMNL2 | formin-like 2 | 0.0695844 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0659396 |
| OSMR | oncostatin M receptor | 0.0659367 |
| MED13 | mediator complex subunit 13 | 0.0636747 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0615437 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0566956 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0566617 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0552599 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0551618 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0549566 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0537833 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0503177 |
| HDAC9 | histone deacetylase 9 | 0.0498079 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0492089 |
| SEPTIN2 | septin 2 | 0.0481249 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0467563 |
| CEP250 | centrosomal protein 250kDa | 0.046317 |
| SMYD3 | SET and MYND domain containing 3 | 0.0453575 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.044935 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0445777 |
| CALR | calreticulin | 0.0444414 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0437985 |
| MSN | moesin | 0.0434066 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0430919 |
| PTMA | prothymosin, alpha | 0.0429236 |
| ATXN2 | ataxin 2 | 0.0424549 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0416655 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0414338 |
| RAB5A | RAB5A, member RAS oncogene family | 0.040942 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0400466 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0398619 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0397924 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0396828 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0395064 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0394492 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.038757 |
| CAPRIN2 | caprin family member 2 | 0.0383982 |
| CDCP1 | CUB domain containing protein 1 | 0.0382607 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0380572 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0376538 |
| PRKCE | protein kinase C, epsilon | 0.0376423 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0371061 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0364114 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0361288 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0361223 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.036122 |
| ATM | ATM serine/threonine kinase | 0.0354987 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0353628 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0351597 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0350101 |
| CLTC | clathrin, heavy chain (Hc) | 0.0345614 |
| HJURP | Holliday junction recognition protein | 0.0343374 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0343269 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0340989 |
| RBM39 | RNA binding motif protein 39 | 0.0340074 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0339508 |
| VMP1 | vacuole membrane protein 1 | 0.0338015 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0334842 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326425 |
| ADM | adrenomedullin | 0.0325949 |
| VIM | vimentin | 0.032161 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.031784 |
| ATP13A3 | ATPase type 13A3 | 0.0317405 |
| CD2AP | CD2-associated protein | 0.0316082 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0314669 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0311602 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0308983 |
| LDHA | lactate dehydrogenase A | 0.0303911 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0302932 |
| GOLT1B | golgi transport 1B | 0.0299624 |
| SCFD1 | sec1 family domain containing 1 | 0.0297311 |
| MATR3 | matrin 3 | 0.0294402 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0291209 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0290756 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0289573 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0287617 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0287033 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0281927 |
| RBMX | RNA binding motif protein, X-linked | 0.0279972 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0278763 |
| SETD5 | SET domain containing 5 | 0.0276965 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0276559 |
| HM13 | histocompatibility (minor) 13 | 0.0274275 |
| FAM193A | family with sequence similarity 193, member A | 0.0273383 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0272318 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0272272 |
| ATG7 | autophagy related 7 | 0.0269357 |
| PHF20 | PHD finger protein 20 | 0.0268938 |
| ARFGEF3 | ARFGEF family member 3 | 0.0268152 |
| RPL9 | ribosomal protein L9 | 0.026814 |
| CEP290 | centrosomal protein 290kDa | 0.026808 |
| EPN2 | epsin 2 | 0.0267968 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.0267871 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.110177 |
| TPI1 | triosephosphate isomerase 1 | -0.0531907 |
| ANXA2 | annexin A2 | -0.0488483 |
| POTEF | POTE ankyrin domain family, member F | -0.047469 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0426388 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0412697 |
| IER3 | immediate early response 3 | -0.0354464 |
| AHNAK | AHNAK nucleoprotein | -0.0325135 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312578 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0311247 |
| DEK | DEK proto-oncogene | -0.0308825 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0301789 |
| SYCP2 | synaptonemal complex protein 2 | -0.0301625 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0296315 |
| CENPF | centromere protein F, 350/400kDa | -0.0292824 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0291295 |
| MT2A | metallothionein 2A | -0.0286561 |
| TMEM123 | transmembrane protein 123 | -0.0272318 |
| CDK6 | cyclin-dependent kinase 6 | -0.0271499 |
| FMR1 | fragile X mental retardation 1 | -0.0269886 |
| NUP54 | nucleoporin 54kDa | -0.0267414 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0266415 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0264249 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0263311 |
| KIF23 | kinesin family member 23 | -0.0261041 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.02576 |
| SBF2 | SET binding factor 2 | -0.0256001 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0253214 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0247343 |
| KNTC1 | kinetochore associated 1 | -0.0247237 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit | -0.0244675 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0243252 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0241323 |
| RPL35A | ribosomal protein L35a | -0.0241215 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0239939 |
| MT1X | metallothionein 1X | -0.0239312 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0237069 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0233737 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0232061 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0231806 |
| TUBA1B | tubulin, alpha 1b | -0.0230721 |
| PFN1 | profilin 1 | -0.0230347 |
| RAD21 | RAD21 homolog (S. pombe) | -0.022737 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0227307 |
| ANLN | anillin, actin binding protein | -0.0224122 |
| RNF145 | ring finger protein 145 | -0.0222804 |
| H3-3B | H3.3 histone B | -0.0222232 |
| RSBN1 | round spermatid basic protein 1 | -0.0220357 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0219304 |
| TXNRD1 | thioredoxin reductase 1 | -0.0218774 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0215555 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0215325 |
| GPC6 | glypican 6 | -0.0212595 |
| PER1 | period circadian clock 1 | -0.0211496 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0210619 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.02094 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0208596 |
| PAPOLA | poly(A) polymerase alpha | -0.0206637 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | -0.0205435 |
| NHLRC2 | NHL repeat containing 2 | -0.0203614 |
| FAM3C | family with sequence similarity 3, member C | -0.02015 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.0200526 |
| ZFR | zinc finger RNA binding protein | -0.0198457 |
| PANX1 | pannexin 1 | -0.019791 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0197519 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0197182 |
| INVS | inversin | -0.0196677 |
| CANX | calnexin | -0.0196386 |
| RPS19 | ribosomal protein S19 | -0.0195995 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0194067 |
| NAV2 | neuron navigator 2 | -0.0193917 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0192123 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0192078 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0189854 |
| ABHD17B | abhydrolase domain containing 17B | -0.018945 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0188699 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0188527 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | -0.0187148 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0186594 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.018624 |
| CD164 | CD164 molecule, sialomucin | -0.0186001 |
| UBQLN1 | ubiquilin 1 | -0.0185532 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0184504 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0182964 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.018289 |
| PDE8A | phosphodiesterase 8A | -0.0181874 |
| ARF1 | ADP-ribosylation factor 1 | -0.0181641 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0181319 |
| PCED1B | PC-esterase domain containing 1B | -0.0181138 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | -0.0180844 |
| RPS11 | ribosomal protein S11 | -0.0180096 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0180052 |
| TCF12 | transcription factor 12 | -0.0179855 |
| UBB | ubiquitin B | -0.017985 |
| RPL18 | ribosomal protein L18 | -0.0179717 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0179458 |
| MKI67 | marker of proliferation Ki-67 | -0.0178713 |
| MORF4L1 | mortality factor 4 like 1 | -0.0178366 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.017778 |
| ZFP64 | ZFP64 zinc finger protein | -0.0177448 |
