| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.13275 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.069009 |
| MACC1 | metastasis associated in colon cancer 1 | 0.055432 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0424684 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0408845 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0394035 |
| BRD2 | bromodomain containing 2 | 0.0354766 |
| EZR | ezrin | 0.0354198 |
| KRT8 | keratin 8, type II | 0.0338754 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.031867 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0308717 |
| CCNL1 | cyclin L1 | 0.0302116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298994 |
| PCBP2 | poly(rC) binding protein 2 | 0.0296882 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0279762 |
| TMF1 | TATA element modulatory factor 1 | 0.0276788 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0265856 |
| SNX9 | sorting nexin 9 | 0.0260731 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0257707 |
| MYO10 | myosin X | 0.0248975 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0247579 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0245948 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0245667 |
| XPO1 | exportin 1 | 0.0244306 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0239579 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0238881 |
| AFDN | afadin, adherens junction formation factor | 0.0238703 |
| PTK2 | protein tyrosine kinase 2 | 0.0237619 |
| ZNF292 | zinc finger protein 292 | 0.0235906 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0232649 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.023103 |
| COG5 | component of oligomeric golgi complex 5 | 0.0228753 |
| KRT18 | keratin 18, type I | 0.0220349 |
| MED13L | mediator complex subunit 13-like | 0.0214395 |
| MKRN1 | makorin ring finger protein 1 | 0.0213197 |
| UBC | ubiquitin C | 0.0211666 |
| NCKAP1 | NCK-associated protein 1 | 0.0210516 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.020883 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0207037 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.020492 |
| CLTC | clathrin, heavy chain (Hc) | 0.0201105 |
| YTHDC1 | YTH domain containing 1 | 0.0199818 |
| NPTN | neuroplastin | 0.0198938 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0198084 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.01951 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0193411 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0190459 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.019027 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0189558 |
| MYO5B | myosin VB | 0.0186383 |
| RBM25 | RNA binding motif protein 25 | 0.0186169 |
| FAT1 | FAT atypical cadherin 1 | 0.018536 |
| FNBP4 | formin binding protein 4 | 0.0182975 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0182741 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0182641 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0182117 |
| RBM5 | RNA binding motif protein 5 | 0.0182073 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0181881 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0179843 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0179634 |
| INSIG1 | insulin induced gene 1 | 0.0178306 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0177293 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0175353 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0174949 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0174236 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0174078 |
| WDR43 | WD repeat domain 43 | 0.0173573 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0172372 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0172083 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0171653 |
| GOLT1B | golgi transport 1B | 0.0171178 |
| ZFP36 | ZFP36 ring finger protein | 0.0170629 |
| ECT2 | epithelial cell transforming 2 | 0.017028 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0170036 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0169853 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0168794 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0168739 |
| NDRG1 | N-myc downstream regulated 1 | 0.016787 |
| DSPP | dentin sialophosphoprotein | 0.0167852 |
| H1-0 | H1.0 linker histone | 0.0167434 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0166853 |
| TMEM87A | transmembrane protein 87A | 0.0166808 |
| B2M | beta-2-microglobulin | 0.0166538 |
| RIOK3 | RIO kinase 3 | 0.0165898 |
| PDS5B | PDS5 cohesin associated factor B | 0.0165656 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.016562 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0164801 |
| USP6NL | USP6 N-terminal like | 0.0164538 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0164306 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0160432 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.0159729 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0159695 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0159489 |
| OXR1 | oxidation resistance 1 | 0.0158533 |
| KRT19 | keratin 19, type I | 0.015785 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0157415 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0154727 |
| EPCAM | epithelial cell adhesion molecule | 0.0154438 |
| TOB1 | transducer of ERBB2, 1 | 0.015408 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0154071 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.203355 |
| TMSB10 | thymosin beta 10 | -0.116004 |
| RPL35A | ribosomal protein L35a | -0.111191 |
| FTL | ferritin, light polypeptide | -0.10546 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0973336 |
| RPS21 | ribosomal protein S21 | -0.0591813 |
| RPLP1 | ribosomal protein, large, P1 | -0.0581981 |
| GNAS | GNAS complex locus | -0.0581606 |
| RPS6 | ribosomal protein S6 | -0.0508901 |
| RPLP2 | ribosomal protein, large, P2 | -0.0506636 |
| RPL31 | ribosomal protein L31 | -0.0473736 |
| RPS25 | ribosomal protein S25 | -0.0465093 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0460778 |
| IER3 | immediate early response 3 | -0.044703 |
| ACTG1 | actin gamma 1 | -0.0446016 |
| RPL34 | ribosomal protein L34 | -0.0442791 |
| RPS13 | ribosomal protein S13 | -0.0434638 |
| RPS24 | ribosomal protein S24 | -0.0434431 |
| RPL37A | ribosomal protein L37a | -0.0433566 |
| RPS12 | ribosomal protein S12 | -0.0414405 |
| RPS29 | ribosomal protein S29 | -0.0398191 |
| RPS27A | ribosomal protein S27a | -0.0373001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0360407 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0358399 |
| EGR1 | early growth response 1 | -0.0355801 |
| FRMD5 | FERM domain containing 5 | -0.0332852 |
| HLA-A | major histocompatibility complex, class I, A | -0.0329931 |
| RPS19 | ribosomal protein S19 | -0.0326104 |
| RPL28 | ribosomal protein L28 | -0.0323831 |
| RPS8 | ribosomal protein S8 | -0.0321949 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0318046 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0312175 |
| RPL38 | ribosomal protein L38 | -0.0297 |
| RPS23 | ribosomal protein S23 | -0.0295741 |
| EHBP1 | EH domain binding protein 1 | -0.0291887 |
| RPL23 | ribosomal protein L23 | -0.0289633 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0287882 |
| SDC4 | syndecan 4 | -0.0285915 |
| INTS6 | integrator complex subunit 6 | -0.0284514 |
| RPL36A | ribosomal protein L36a | -0.0284084 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0272263 |
| RPL37 | ribosomal protein L37 | -0.0271507 |
| HLA-B | major histocompatibility complex, class I, B | -0.026149 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0259301 |
| RPL36 | ribosomal protein L36 | -0.025726 |
| RPL9 | ribosomal protein L9 | -0.0254113 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0254057 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0252968 |
| VCL | vinculin | -0.0247891 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0245725 |
| RPS11 | ribosomal protein S11 | -0.024232 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0239553 |
| ETV6 | ets variant 6 | -0.0237597 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0234628 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0234138 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0232706 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0228429 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0228068 |
| RPL12 | ribosomal protein L12 | -0.0227982 |
| CUX1 | cut-like homeobox 1 | -0.0226333 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0226293 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0221421 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0213564 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0208236 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0208013 |
| RPS14 | ribosomal protein S14 | -0.0206803 |
| RIGI | RNA sensor RIG-I | -0.0204899 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0200521 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0200218 |
| CDK12 | cyclin-dependent kinase 12 | -0.0199001 |
| CDK13 | cyclin-dependent kinase 13 | -0.0198905 |
| RRBP1 | ribosome binding protein 1 | -0.0196884 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0195001 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0192412 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0188274 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.018727 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0186587 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0185779 |
| PRPF6 | pre-mRNA processing factor 6 | -0.0184061 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0182458 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.018231 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0181397 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0181261 |
| SELENOK | selenoprotein K | -0.0180734 |
| CADPS | Ca++-dependent secretion activator | -0.0180223 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0179158 |
| HDAC8 | histone deacetylase 8 | -0.0178345 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0178126 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0176722 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0175924 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.017583 |
| FBXO34 | F-box protein 34 | -0.0174495 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.017432 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.017428 |
| RPL27 | ribosomal protein L27 | -0.0174169 |
| MYO1E | myosin IE | -0.017344 |
| BCL2L1 | BCL2-like 1 | -0.0173084 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0172782 |
| RPL7A | ribosomal protein L7a | -0.0172378 |
| TPM4 | tropomyosin 4 | -0.017153 |
