| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.169368 |
| LMO7 | LIM domain 7 | 0.155594 |
| ANXA1 | annexin A1 | 0.142957 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.122298 |
| EZR | ezrin | 0.116368 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.106215 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0924143 |
| PTMA | prothymosin, alpha | 0.08678 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0775484 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0761923 |
| DSPP | dentin sialophosphoprotein | 0.0730309 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0647491 |
| OXR1 | oxidation resistance 1 | 0.0629317 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0619825 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0618664 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0555751 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0517528 |
| RUNX2 | runt-related transcription factor 2 | 0.0515866 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0510452 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0507603 |
| LAMC2 | laminin, gamma 2 | 0.0465981 |
| AREG | amphiregulin | 0.0463279 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0460873 |
| FAT1 | FAT atypical cadherin 1 | 0.0454627 |
| GOLGA4 | golgin A4 | 0.0451411 |
| LAMB3 | laminin, beta 3 | 0.0450056 |
| LDHA | lactate dehydrogenase A | 0.0450014 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0449248 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0448478 |
| RBM25 | RNA binding motif protein 25 | 0.0431135 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0427897 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0427021 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0421233 |
| TXNRD1 | thioredoxin reductase 1 | 0.0420432 |
| OGA | O-GlcNAcase | 0.0418286 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0414247 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0414093 |
| SERINC5 | serine incorporator 5 | 0.041339 |
| TOP1 | topoisomerase (DNA) I | 0.0412353 |
| HDAC2 | histone deacetylase 2 | 0.0412032 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0383498 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.03751 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.03731 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0366795 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.036334 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0360861 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0356837 |
| VMP1 | vacuole membrane protein 1 | 0.0355182 |
| ACTN4 | actinin, alpha 4 | 0.0353354 |
| CD9 | CD9 molecule | 0.0351394 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0348285 |
| FMNL2 | formin-like 2 | 0.0344555 |
| WDR43 | WD repeat domain 43 | 0.0340655 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0340517 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0337652 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0336667 |
| KRT18 | keratin 18, type I | 0.0335143 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0333953 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0328753 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0328691 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0327163 |
| NCKAP1 | NCK-associated protein 1 | 0.0320876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0318572 |
| FERMT1 | fermitin family member 1 | 0.031737 |
| ATL2 | atlastin GTPase 2 | 0.0316668 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0315095 |
| NEMF | nuclear export mediator factor | 0.0312423 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0311035 |
| ANLN | anillin, actin binding protein | 0.0310432 |
| RNF43 | ring finger protein 43 | 0.0310187 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0308594 |
| GTF2I | general transcription factor IIi | 0.0302648 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0299065 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0296685 |
| MED13L | mediator complex subunit 13-like | 0.0295278 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0292554 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0292111 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.029184 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0291436 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0290275 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0289618 |
| CLTC | clathrin, heavy chain (Hc) | 0.0288892 |
| ANXA11 | annexin A11 | 0.0287599 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0285599 |
| EPCAM | epithelial cell adhesion molecule | 0.0284148 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0280912 |
| BBX | bobby sox homolog (Drosophila) | 0.0280262 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0280054 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0279061 |
| RANBP2 | RAN binding protein 2 | 0.0278936 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.027603 |
| FNBP4 | formin binding protein 4 | 0.0275791 |
| NDRG1 | N-myc downstream regulated 1 | 0.0269946 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.026991 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0268415 |
| USP3 | ubiquitin specific peptidase 3 | 0.0267016 |
| TXNIP | thioredoxin interacting protein | 0.0267002 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0265537 |
| RAB10 | RAB10, member RAS oncogene family | 0.0265491 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.026451 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.0966661 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0878339 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0800115 |
| IER3 | immediate early response 3 | -0.0688146 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0508633 |
| FHIT | fragile histidine triad | -0.0452104 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0409517 |
| RPS8 | ribosomal protein S8 | -0.0392157 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0352648 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0277258 |
| S100A10 | S100 calcium binding protein A10 | -0.02499 |
| RPL23 | ribosomal protein L23 | -0.0248943 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0233367 |
| SQSTM1 | sequestosome 1 | -0.0230348 |
| VCL | vinculin | -0.0228166 |
| RPLP1 | ribosomal protein, large, P1 | -0.0226467 |
| HMGA2 | high mobility group AT-hook 2 | -0.0222268 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0221248 |
| ABR | active BCR-related | -0.0219832 |
| GOLGB1 | golgin B1 | -0.021121 |
| EXT1 | exostosin glycosyltransferase 1 | -0.020116 |
| RPL5 | ribosomal protein L5 | -0.0200482 |
| RPS12 | ribosomal protein S12 | -0.0198434 |
| HMGA1 | high mobility group AT-hook 1 | -0.0197865 |
| RPS19 | ribosomal protein S19 | -0.0194325 |
| RPL37 | ribosomal protein L37 | -0.0188724 |
| RPS14 | ribosomal protein S14 | -0.018782 |
| POTEF | POTE ankyrin domain family, member F | -0.0183483 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0181975 |
| AK1 | adenylate kinase 1 | -0.0176832 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0176441 |
| RPL12 | ribosomal protein L12 | -0.0175323 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0173826 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0172723 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0167267 |
| RPL4 | ribosomal protein L4 | -0.0166582 |
| RPS10 | ribosomal protein S10 | -0.0165847 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.016503 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0162579 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0161967 |
| WWOX | WW domain containing oxidoreductase | -0.0158067 |
| SGMS2 | sphingomyelin synthase 2 | -0.015639 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0156334 |
| RCOR1 | REST corepressor 1 | -0.0155957 |
| RPL35A | ribosomal protein L35a | -0.0154016 |
| RPS2 | ribosomal protein S2 | -0.0153723 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0152315 |
| RRM2 | ribonucleotide reductase M2 | -0.0151539 |
| RPL35 | ribosomal protein L35 | -0.0150523 |
| LAMA4 | laminin, alpha 4 | -0.0144917 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0143093 |
| B2M | beta-2-microglobulin | -0.0139434 |
| RPS23 | ribosomal protein S23 | -0.0138829 |
| RPS6 | ribosomal protein S6 | -0.0138476 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0137524 |
| RPL27 | ribosomal protein L27 | -0.0136329 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0136277 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0134066 |
| MT2A | metallothionein 2A | -0.0133981 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0131853 |
| RPS4X | ribosomal protein S4, X-linked | -0.0128567 |
| TUBB | tubulin, beta class I | -0.0128165 |
| SERTAD2 | SERTA domain containing 2 | -0.0127536 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0126964 |
| SMYD3 | SET and MYND domain containing 3 | -0.0125301 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0124678 |
| RPS20 | ribosomal protein S20 | -0.0123144 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0123068 |
| RYBP | RING1 and YY1 binding protein | -0.0121499 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0121089 |
| RPS16 | ribosomal protein S16 | -0.0120189 |
| ZFP36 | ZFP36 ring finger protein | -0.0116449 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0116364 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0115862 |
| TUBA1B | tubulin, alpha 1b | -0.0115608 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | -0.0115362 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0115359 |
| CDK13 | cyclin-dependent kinase 13 | -0.0115043 |
| RPS27 | ribosomal protein S27 | -0.0114638 |
| BSG | basigin (Ok blood group) | -0.0114482 |
| EMP1 | epithelial membrane protein 1 | -0.0114443 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0113682 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0113395 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0112733 |
| RPS24 | ribosomal protein S24 | -0.0112323 |
| PFN1 | profilin 1 | -0.0110787 |
| RPL9 | ribosomal protein L9 | -0.0110449 |
| HMGB1 | high mobility group box 1 | -0.0109013 |
| EFNA5 | ephrin-A5 | -0.0107803 |
| RPL30 | ribosomal protein L30 | -0.010765 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0107541 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0106862 |
| MACROD2 | MACRO domain containing 2 | -0.0104925 |
| EGR3 | early growth response 3 | -0.0104871 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0103906 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0103173 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0103135 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0102894 |
| HELLS | helicase, lymphoid-specific | -0.010277 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0102584 |
