| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A secondary amino compound having methyl and 3-(2-methylphenoxy)-3-phenylpropan-1-yl substituents. (Chemical Entities of Biological Interest Ontology, CHEBI_127342) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/54841 |
| Similar Terms | |
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199 proteins with high or low expression in Atomoxetine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 2.94 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 2.86 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 1.31 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.79 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.62 |
| TSPAN3 | tetraspanin 3 | 0.59 |
| BCL2L12 | BCL2-like 12 (proline rich) | 0.53 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.5 |
| TCF19 | transcription factor 19 | 0.49 |
| LRRC58 | leucine rich repeat containing 58 | 0.46 |
| APOB | apolipoprotein B | 0.45 |
| CDK10 | cyclin-dependent kinase 10 | 0.44 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.44 |
| CHN1 | chimerin 1 | 0.42 |
| MT1F | metallothionein 1F | 0.42 |
| VAMP4 | vesicle-associated membrane protein 4 | 0.4 |
| ZNF302 | zinc finger protein 302 | 0.39 |
| TBC1D12 | TBC1 domain family, member 12 | 0.39 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.39 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.39 |
| CEP57 | centrosomal protein 57kDa | 0.39 |
| RMDN2 | regulator of microtubule dynamics 2 | 0.39 |
| MCRIP2 | MAPK regulated corepressor interacting protein 2 | 0.37 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | 0.37 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.37 |
| UBTD1 | ubiquitin domain containing 1 | 0.37 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | 0.37 |
| ZNF740 | zinc finger protein 740 | 0.36 |
| C9ORF40 | chromosome 9 open reading frame 40 | 0.36 |
| MTSS2 | MTSS I-BAR domain containing 2 | 0.35 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.35 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | 0.34 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.33 |
| MKRN1 | makorin ring finger protein 1 | 0.33 |
| HYKK | hydroxylysine kinase | 0.33 |
| RFLNB | refilin B | 0.32 |
| SCRN3 | secernin 3 | 0.31 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 0.31 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.31 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | 0.31 |
| HSPA1L | heat shock 70kDa protein 1-like | 0.31 |
| REX1BD | required for excision 1-B domain containing | 0.3 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.3 |
| DENND3 | DENN/MADD domain containing 3 | 0.3 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.29 |
| CHRD | chordin | 0.29 |
| TBC1D30 | TBC1 domain family, member 30 | 0.29 |
| ATG4A | autophagy related 4A, cysteine peptidase | 0.29 |
| FHIT | fragile histidine triad | 0.29 |
| SLC25A39 | solute carrier family 25, member 39 | 0.29 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.28 |
| SULF2 | sulfatase 2 | 0.28 |
| RAB26 | RAB26, member RAS oncogene family | 0.28 |
| ABHD18 | abhydrolase domain containing 18 | 0.28 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.28 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | 0.27 |
| KBTBD6 | kelch repeat and BTB (POZ) domain containing 6 | 0.27 |
| MBTD1 | mbt domain containing 1 | 0.27 |
| C16ORF72 | chromosome 16 open reading frame 72 | 0.27 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.27 |
| CEP104 | centrosomal protein 104kDa | 0.27 |
| SHFL | shiftless antiviral inhibitor of ribosomal frameshifting | 0.27 |
| ZNF430 | zinc finger protein 430 | 0.27 |
| ZDHHC12 | zinc finger, DHHC-type containing 12 | 0.26 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.26 |
| ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | 0.26 |
| SEPTIN4 | septin 4 | 0.26 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.26 |
| UBE2F | ubiquitin-conjugating enzyme E2F (putative) | 0.26 |
| SYTL2 | synaptotagmin-like 2 | 0.26 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.25 |
| MYH15 | myosin, heavy chain 15 | 0.25 |
| RCOR2 | REST corepressor 2 | 0.25 |
| MKRN3 | makorin ring finger protein 3 | 0.25 |
| TMEM64 | transmembrane protein 64 | 0.25 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.25 |
| CENPI | centromere protein I | 0.25 |
| BMP4 | bone morphogenetic protein 4 | 0.25 |
| MYPOP | Myb-related transcription factor, partner of profilin | 0.25 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.25 |
| CD82 | CD82 molecule | 0.25 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.25 |
| GOLGA4 | golgin A4 | 0.25 |
| ZBTB4 | zinc finger and BTB domain containing 4 | 0.25 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.24 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.24 |
| TMEM128 | transmembrane protein 128 | 0.24 |
| CPA4 | carboxypeptidase A4 | 0.24 |
| ATP9B | ATPase, class II, type 9B | 0.24 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 | 0.24 |
| RAB29 | RAB29, member RAS oncogene family | 0.24 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.23 |
| BAIAP2 | BAI1-associated protein 2 | 0.23 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | 0.23 |
| C15ORF61 | chromosome 15 open reading frame 61 | 0.23 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.23 |
| TRAF3 | TNF receptor-associated factor 3 | 0.23 |
| ALG14 | ALG14, UDP-N-acetylglucosaminyltransferase subunit | 0.23 |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 | 0.23 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRAME | preferentially expressed antigen in melanoma | -3.77 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -1.73 |
| SETD9 | SET domain containing 9 | -1.46 |
| MEX3A | mex-3 RNA binding family member A | -1.12 |
| ZNF397 | zinc finger protein 397 | -0.9 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.83 |
| TSPAN33 | tetraspanin 33 | -0.81 |
| NPHP3 | nephronophthisis 3 (adolescent) | -0.73 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.65 |
| LIPH | lipase, member H | -0.59 |
| WWC3 | WWC family member 3 | -0.57 |
| TDRD9 | tudor domain containing 9 | -0.57 |
| ZNF691 | zinc finger protein 691 | -0.53 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.53 |
| CCPG1 | cell cycle progression 1 | -0.51 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.51 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.5 |
| OSCP1 | organic solute carrier partner 1 | -0.49 |
| SARDH | sarcosine dehydrogenase | -0.49 |
| HPCAL4 | hippocalcin like 4 | -0.48 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | -0.47 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | -0.43 |
| C6ORF141 | chromosome 6 open reading frame 141 | -0.41 |
| RUBCN | rubicon autophagy regulator | -0.4 |
| ZNF777 | zinc finger protein 777 | -0.4 |
| RCOR1 | REST corepressor 1 | -0.39 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.39 |
| MAP2 | microtubule-associated protein 2 | -0.38 |
| PIAS3 | protein inhibitor of activated STAT, 3 | -0.38 |
| GON7 | GON7 subunit of KEOPS complex | -0.38 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -0.36 |
| TMEM132A | transmembrane protein 132A | -0.35 |
| NOTCH3 | notch 3 | -0.35 |
| ZFHX4 | zinc finger homeobox 4 | -0.35 |
| CMC4 | C-x(9)-C motif containing 4 | -0.34 |
| ENO1 | enolase 1, (alpha) | -0.34 |
| IFT43 | intraflagellar transport 43 | -0.33 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 | -0.33 |
| OGG1 | 8-oxoguanine DNA glycosylase | -0.33 |
| DEPDC5 | DEP domain containing 5 | -0.33 |
| PDIK1L | PDLIM1 interacting kinase 1 like | -0.33 |
| GIGYF1 | GRB10 interacting GYF protein 1 | -0.33 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.32 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.32 |
| RNF139 | ring finger protein 139 | -0.31 |
| CLEC16A | C-type lectin domain family 16, member A | -0.31 |
| KIAA1109 | KIAA1109 | -0.31 |
| CBR1 | carbonyl reductase 1 | -0.31 |
| EED | embryonic ectoderm development | -0.31 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.31 |
| CRY2 | cryptochrome circadian clock 2 | -0.3 |
| ZNF14 | zinc finger protein 14 | -0.3 |
| FKBPL | FK506 binding protein like | -0.3 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | -0.3 |
| MT-CO2 | cytochrome c oxidase subunit II | -0.29 |
| MYBPC2 | myosin binding protein C, fast type | -0.29 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.29 |
| TMEM41B | transmembrane protein 41B | -0.29 |
| TMSB10 | thymosin beta 10 | -0.29 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.29 |
| HYPK | huntingtin interacting protein K | -0.29 |
| RUNX3 | runt-related transcription factor 3 | -0.28 |
| NAAA | N-acylethanolamine acid amidase | -0.28 |
| IER2 | immediate early response 2 | -0.28 |
| TMEM101 | transmembrane protein 101 | -0.28 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -0.28 |
| PRG4 | proteoglycan 4 | -0.28 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.28 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | -0.27 |
| TROAP | trophinin associated protein | -0.27 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | -0.27 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.27 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | -0.27 |
| RETREG2 | reticulophagy regulator family member 2 | -0.26 |
| SPNS1 | spinster homolog 1 (Drosophila) | -0.26 |
| TMEM208 | transmembrane protein 208 | -0.26 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -0.26 |
| TET3 | tet methylcytosine dioxygenase 3 | -0.26 |
| TMEM63B | transmembrane protein 63B | -0.25 |
| MKS1 | Meckel syndrome, type 1 | -0.25 |
| GPN2 | GPN-loop GTPase 2 | -0.25 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.25 |
| MEST | mesoderm specific transcript | -0.25 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | -0.24 |
| PWWP2B | PWWP domain containing 2B | -0.24 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | -0.24 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 | -0.24 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.24 |
| HSPA12B | heat shock 70kD protein 12B | -0.24 |
| ONECUT3 | one cut homeobox 3 | -0.24 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -0.24 |
| PTMA | prothymosin, alpha | -0.24 |
| CRELD1 | cysteine-rich with EGF-like domains 1 | -0.24 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.24 |
| TYRO3 | TYRO3 protein tyrosine kinase | -0.24 |
| FAM185A | family with sequence similarity 185, member A | -0.23 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.23 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 | -0.23 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.23 |
