| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0724504 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0534754 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0401615 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0316197 |
| FBN1 | fibrillin 1 | 0.0312973 |
| ATP13A3 | ATPase type 13A3 | 0.0302559 |
| COL3A1 | collagen, type III, alpha 1 | 0.030036 |
| SBF2 | SET binding factor 2 | 0.0269714 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0239913 |
| NAV2 | neuron navigator 2 | 0.0230961 |
| OGA | O-GlcNAcase | 0.0230595 |
| PLAT | plasminogen activator, tissue | 0.0226637 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0225944 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0214014 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.020547 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0198008 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0192471 |
| PODXL | podocalyxin-like | 0.018853 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0181618 |
| AFDN | afadin, adherens junction formation factor | 0.0172969 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0169813 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0168361 |
| HLA-A | major histocompatibility complex, class I, A | 0.0168 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0167301 |
| USP34 | ubiquitin specific peptidase 34 | 0.0166089 |
| STC1 | stanniocalcin 1 | 0.0163845 |
| FLNB | filamin B, beta | 0.0153923 |
| SEPTIN9 | septin 9 | 0.0151895 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0149077 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0146487 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0146072 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0141089 |
| FNIP1 | folliculin interacting protein 1 | 0.0140302 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0139921 |
| EGFR | epidermal growth factor receptor | 0.0139252 |
| LOX | lysyl oxidase | 0.013716 |
| CD109 | CD109 molecule | 0.0136689 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0136088 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0135709 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0135612 |
| NGLY1 | N-glycanase 1 | 0.0132812 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0129256 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0128761 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0126533 |
| C1D | C1D nuclear receptor corepressor | 0.012509 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0124804 |
| AUTS2 | autism susceptibility candidate 2 | 0.01241 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0119814 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0117756 |
| MYO9A | myosin IXA | 0.0116536 |
| ZNF654 | zinc finger protein 654 | 0.0116472 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0116157 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0115916 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0115233 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0115195 |
| MTSS1 | metastasis suppressor 1 | 0.0114437 |
| FAM219A | family with sequence similarity 219, member A | 0.0114133 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0113833 |
| HDAC9 | histone deacetylase 9 | 0.0113702 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0113265 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0112322 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0112075 |
| RASA2 | RAS p21 protein activator 2 | 0.0111199 |
| WASHC4 | WASH complex subunit 4 | 0.011114 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0109336 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0108812 |
| FRMD5 | FERM domain containing 5 | 0.0106957 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0106078 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0105416 |
| PRELID2 | PRELI domain containing 2 | 0.0104002 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.0103577 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0103375 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0103092 |
| ZNF638 | zinc finger protein 638 | 0.0100455 |
| HIP1 | huntingtin interacting protein 1 | 0.00998587 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00976756 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.00976718 |
| YEATS2 | YEATS domain containing 2 | 0.00976451 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.00948038 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.00946386 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.00945986 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.00939952 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00935624 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00917718 |
| FAR1 | fatty acyl CoA reductase 1 | 0.00908329 |
| STK10 | serine/threonine kinase 10 | 0.00903217 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.00900127 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.00886677 |
| FAM193B | family with sequence similarity 193, member B | 0.00886033 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.00881188 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00879655 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00877936 |
| ZNF148 | zinc finger protein 148 | 0.00877914 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0087619 |
| SETD5 | SET domain containing 5 | 0.00875853 |
| PTEN | phosphatase and tensin homolog | 0.00874848 |
| MYOF | myoferlin | 0.00868396 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.00867732 |
| USP47 | ubiquitin specific peptidase 47 | 0.0086314 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.00857697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204123 |
| TMSB10 | thymosin beta 10 | -0.127332 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12082 |
| VIM | vimentin | -0.100721 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0896216 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0834908 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0749484 |
| S100A10 | S100 calcium binding protein A10 | -0.0700091 |
| MAP1B | microtubule-associated protein 1B | -0.0665808 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0653733 |
| NDRG1 | N-myc downstream regulated 1 | -0.0529321 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0508044 |
| PKM | pyruvate kinase, muscle | -0.0507618 |
| UBC | ubiquitin C | -0.0502797 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0490063 |
| FN1 | fibronectin 1 | -0.0470792 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0414621 |
| CANX | calnexin | -0.0413002 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0389501 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0381771 |
| ANXA2 | annexin A2 | -0.0372001 |
| POTEF | POTE ankyrin domain family, member F | -0.037155 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0369152 |
| S100A6 | S100 calcium binding protein A6 | -0.0367128 |
| LMNA | lamin A/C | -0.035794 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0339468 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0334609 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0331079 |
| MT2A | metallothionein 2A | -0.0330806 |
| RIGI | RNA sensor RIG-I | -0.0328097 |
| COL5A1 | collagen, type V, alpha 1 | -0.0314976 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0313154 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.030975 |
| LDHA | lactate dehydrogenase A | -0.0306136 |
| MX2 | MX dynamin-like GTPase 2 | -0.0303959 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0299972 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0297027 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0294536 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0285521 |
| FTL | ferritin, light polypeptide | -0.0279514 |
| HLA-B | major histocompatibility complex, class I, B | -0.0279007 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0272095 |
| TPM4 | tropomyosin 4 | -0.027026 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266417 |
| SEPTIN7 | septin 7 | -0.0259736 |
| CALR | calreticulin | -0.0257833 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0254188 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0250449 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0247342 |
| BSG | basigin (Ok blood group) | -0.0244043 |
| AHNAK | AHNAK nucleoprotein | -0.0242988 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0238875 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0238161 |
| SP100 | SP100 nuclear antigen | -0.0237763 |
| NAV1 | neuron navigator 1 | -0.0233993 |
| CD44 | CD44 molecule (Indian blood group) | -0.0233678 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0227693 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0226084 |
| PFN1 | profilin 1 | -0.0220305 |
| PRSS23 | protease, serine, 23 | -0.0217534 |
| ENO1 | enolase 1, (alpha) | -0.0214066 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0213818 |
| RPL28 | ribosomal protein L28 | -0.0213335 |
| HLA-C | major histocompatibility complex, class I, C | -0.0212439 |
| B2M | beta-2-microglobulin | -0.0210757 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0210515 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0210327 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0208428 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0204154 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0200031 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0198907 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0197184 |
| CENPF | centromere protein F, 350/400kDa | -0.019182 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0191374 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0189985 |
| SEC61G | Sec61 gamma subunit | -0.0189675 |
| RRBP1 | ribosome binding protein 1 | -0.018661 |
| ADM | adrenomedullin | -0.018594 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0185589 |
| IL7R | interleukin 7 receptor | -0.0183676 |
| ACTG1 | actin gamma 1 | -0.0183519 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0182148 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0180695 |
| PLXNA2 | plexin A2 | -0.0179106 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0178818 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0178638 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0177544 |
| SQSTM1 | sequestosome 1 | -0.0176146 |
| CDH13 | cadherin 13 | -0.0172297 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0170617 |
| TPM1 | tropomyosin 1 (alpha) | -0.0170305 |
| RPL35A | ribosomal protein L35a | -0.0168554 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0167769 |
| SUCNR1 | succinate receptor 1 | -0.0166951 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0165928 |
| FSTL1 | follistatin-like 1 | -0.0164761 |
| PGK1 | phosphoglycerate kinase 1 | -0.0163895 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0161331 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0160546 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0160487 |
