| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.226189 |
| HLA-A | major histocompatibility complex, class I, A | 0.0521527 |
| PCBP2 | poly(rC) binding protein 2 | 0.0487717 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.045143 |
| CPOX | coproporphyrinogen oxidase | 0.0343486 |
| HDGF | hepatoma-derived growth factor | 0.0306859 |
| TXNRD1 | thioredoxin reductase 1 | 0.0300173 |
| CCNL1 | cyclin L1 | 0.0292716 |
| TMEM41B | transmembrane protein 41B | 0.0290649 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0269273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0256157 |
| RPS12 | ribosomal protein S12 | 0.025593 |
| CLDND1 | claudin domain containing 1 | 0.0246969 |
| VMP1 | vacuole membrane protein 1 | 0.0245445 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0240608 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0236969 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0235646 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0233311 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0228156 |
| NEBL | nebulette | 0.0225378 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0215254 |
| CCN2 | cellular communication network factor 2 | 0.0206058 |
| MED13L | mediator complex subunit 13-like | 0.0205269 |
| WDR43 | WD repeat domain 43 | 0.0204006 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0203369 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0202792 |
| JMJD1C | jumonji domain containing 1C | 0.0198184 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0195482 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.019301 |
| SSRP1 | structure specific recognition protein 1 | 0.0188681 |
| PREPL | prolyl endopeptidase-like | 0.0188373 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0185095 |
| PNN | pinin, desmosome associated protein | 0.0182828 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0181344 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0180782 |
| MEMO1 | mediator of cell motility 1 | 0.0180276 |
| BCHE | butyrylcholinesterase | 0.0179927 |
| ANKRD12 | ankyrin repeat domain 12 | 0.017043 |
| SESN2 | sestrin 2 | 0.0167466 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0163213 |
| RSF1 | remodeling and spacing factor 1 | 0.0163095 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0162083 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0158743 |
| RPS7 | ribosomal protein S7 | 0.0156902 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0156695 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0153378 |
| MSN | moesin | 0.0150797 |
| NKTR | natural killer cell triggering receptor | 0.0150348 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0149978 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0148552 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.014769 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0146728 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0145061 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.014506 |
| PTEN | phosphatase and tensin homolog | 0.0144437 |
| ANXA1 | annexin A1 | 0.0144316 |
| LEMD3 | LEM domain containing 3 | 0.0144164 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0142748 |
| NUP58 | nucleoporin 58 | 0.0141134 |
| KLHL24 | kelch-like family member 24 | 0.0140946 |
| SERINC1 | serine incorporator 1 | 0.0138836 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0137335 |
| AHR | aryl hydrocarbon receptor | 0.0137218 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0136949 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0135344 |
| CRY1 | cryptochrome circadian clock 1 | 0.0135294 |
| ARRDC3 | arrestin domain containing 3 | 0.0134169 |
| RNF145 | ring finger protein 145 | 0.0134118 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0133262 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0132573 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0132159 |
| POTEF | POTE ankyrin domain family, member F | 0.0131471 |
| ZNF292 | zinc finger protein 292 | 0.0130945 |
| MGAT4C | MGAT4 family, member C | 0.0128809 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0128639 |
| ETNK1 | ethanolamine kinase 1 | 0.0127724 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0126783 |
| CISD1 | CDGSH iron sulfur domain 1 | 0.0126423 |
| TBK1 | TANK-binding kinase 1 | 0.0126331 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.012619 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0125842 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0125292 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0124892 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0123989 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0123135 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0122854 |
| RHOA | ras homolog family member A | 0.0122147 |
| THOC2 | THO complex 2 | 0.0121964 |
| CDK17 | cyclin-dependent kinase 17 | 0.0121304 |
| RBM25 | RNA binding motif protein 25 | 0.0119496 |
| TFG | TRK-fused gene | 0.0119068 |
| VCL | vinculin | 0.0118659 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0118426 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0117879 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0117484 |
| ZNF146 | zinc finger protein 146 | 0.0117074 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.011678 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0116484 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0114831 |
| CLDN1 | claudin 1 | 0.011458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.230787 |
| NLGN1 | neuroligin 1 | -0.166625 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.150644 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.121645 |
| VIM | vimentin | -0.12067 |
| TMSB10 | thymosin beta 10 | -0.103211 |
| ACTG1 | actin gamma 1 | -0.0838476 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0757254 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0690641 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0676672 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0675869 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0661102 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0650442 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0630147 |
| AHNAK | AHNAK nucleoprotein | -0.0597113 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0591073 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0570907 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0568998 |
| CCND1 | cyclin D1 | -0.0551813 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0550555 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0542587 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0496624 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0480266 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0459666 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0457587 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.045629 |
| PTMA | prothymosin, alpha | -0.0432825 |
| HMGA2 | high mobility group AT-hook 2 | -0.0417441 |
| RPLP1 | ribosomal protein, large, P1 | -0.041383 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.040195 |
| PCDH7 | protocadherin 7 | -0.0401433 |
| H1-0 | H1.0 linker histone | -0.0382344 |
| RPS24 | ribosomal protein S24 | -0.0377653 |
| RPL35A | ribosomal protein L35a | -0.0376387 |
| CANX | calnexin | -0.0373993 |
| UBC | ubiquitin C | -0.0367737 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0364509 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0359278 |
| FUS | FUS RNA binding protein | -0.0347522 |
| RPL19 | ribosomal protein L19 | -0.034622 |
| GNAS | GNAS complex locus | -0.0341239 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0338784 |
| RPL34 | ribosomal protein L34 | -0.0331914 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0331737 |
| RRM2 | ribonucleotide reductase M2 | -0.033046 |
| FTL | ferritin, light polypeptide | -0.0325463 |
| LMO7 | LIM domain 7 | -0.0325114 |
| CALR | calreticulin | -0.0306311 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0298059 |
| HDLBP | high density lipoprotein binding protein | -0.0290664 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0288037 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.028398 |
| RPS8 | ribosomal protein S8 | -0.0277271 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0273531 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0272702 |
| ZNF804A | zinc finger protein 804A | -0.0270141 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0268022 |
| TUBB | tubulin, beta class I | -0.0266505 |
| HMGB1 | high mobility group box 1 | -0.0264004 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0261934 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0260526 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0257048 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0253884 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0252951 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0250631 |
| RPL8 | ribosomal protein L8 | -0.0250248 |
| YBX3 | Y box binding protein 3 | -0.0249678 |
| RPL38 | ribosomal protein L38 | -0.0247861 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0243584 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0242684 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.024257 |
| MKI67 | marker of proliferation Ki-67 | -0.023462 |
| UBB | ubiquitin B | -0.0233568 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0231709 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0231614 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0230418 |
| CDK6 | cyclin-dependent kinase 6 | -0.022801 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.022615 |
| DEK | DEK proto-oncogene | -0.0225442 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0223408 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0223034 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0222463 |
| TMEM123 | transmembrane protein 123 | -0.0221421 |
| S100A10 | S100 calcium binding protein A10 | -0.0220698 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0219722 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0218896 |
| YAP1 | Yes-associated protein 1 | -0.0217519 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0217414 |
| BRCA1 | breast cancer 1, early onset | -0.0214361 |
| RPS21 | ribosomal protein S21 | -0.0212228 |
| TUBA1B | tubulin, alpha 1b | -0.0211751 |
| PGK1 | phosphoglycerate kinase 1 | -0.0209392 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.0204394 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0202837 |
| ABI2 | abl-interactor 2 | -0.0202703 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0201804 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0200088 |
| HSPA1B | heat shock 70kDa protein 1B | -0.0200073 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0200032 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0199117 |
