| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0776997 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0716172 |
| LIMA1 | LIM domain and actin binding 1 | 0.0657782 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0639466 |
| PHF3 | PHD finger protein 3 | 0.0630723 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.062861 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0612048 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0611128 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0609698 |
| MYO1E | myosin IE | 0.057892 |
| TMC5 | transmembrane channel-like 5 | 0.0577077 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0528641 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0527522 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0461171 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0454574 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0447004 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0436279 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0408476 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0407974 |
| IFNGR1 | interferon gamma receptor 1 | 0.039453 |
| VMP1 | vacuole membrane protein 1 | 0.0388417 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0382834 |
| ERBIN | erbb2 interacting protein | 0.0357591 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0350922 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0342239 |
| PDZD8 | PDZ domain containing 8 | 0.0342114 |
| STK24 | serine/threonine kinase 24 | 0.0341468 |
| ADIPOR2 | adiponectin receptor 2 | 0.033453 |
| CSTB | cystatin B (stefin B) | 0.0329863 |
| KIF16B | kinesin family member 16B | 0.0328808 |
| AREG | amphiregulin | 0.0327899 |
| SLK | STE20-like kinase | 0.0325175 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0324823 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0319814 |
| COPA | coatomer protein complex, subunit alpha | 0.0316878 |
| JAK1 | Janus kinase 1 | 0.031004 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0306055 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0303271 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0296037 |
| PATJ | PATJ crumbs cell polarity complex component | 0.029354 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0293521 |
| SFTPA2 | surfactant protein A2 | 0.0288402 |
| VEGFA | vascular endothelial growth factor A | 0.0286684 |
| EPCAM | epithelial cell adhesion molecule | 0.0284868 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0284184 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0275954 |
| MUC20 | mucin 20, cell surface associated | 0.0264243 |
| PCED1B | PC-esterase domain containing 1B | 0.0263896 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0261762 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0259073 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0257947 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.025293 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0251014 |
| UBXN4 | UBX domain protein 4 | 0.0250476 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0250148 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0249706 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0249488 |
| PMM2 | phosphomannomutase 2 | 0.0246042 |
| LMO7 | LIM domain 7 | 0.024397 |
| MORF4L1 | mortality factor 4 like 1 | 0.0243385 |
| EHBP1 | EH domain binding protein 1 | 0.0242422 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0241912 |
| DIAPH1 | diaphanous-related formin 1 | 0.0241779 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0241453 |
| TSPAN3 | tetraspanin 3 | 0.0239494 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0239194 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0238355 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0237617 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0237382 |
| TOP1 | topoisomerase (DNA) I | 0.0235247 |
| GOLGB1 | golgin B1 | 0.0235229 |
| KAZN | kazrin, periplakin interacting protein | 0.0234778 |
| CEP350 | centrosomal protein 350kDa | 0.0232967 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0229742 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0229727 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0228182 |
| SPOP | speckle-type POZ protein | 0.0227781 |
| RPS6 | ribosomal protein S6 | 0.0224397 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0223778 |
| DUSP10 | dual specificity phosphatase 10 | 0.0222622 |
| RPS12 | ribosomal protein S12 | 0.0222329 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0220748 |
| FDPS | farnesyl diphosphate synthase | 0.0219924 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0219687 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0219511 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.021629 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0215308 |
| KLF6 | Kruppel-like factor 6 | 0.0209157 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0209083 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0208879 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0208782 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0206241 |
| B2M | beta-2-microglobulin | 0.0204765 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.020378 |
| EREG | epiregulin | 0.0203709 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.0201944 |
| NEK7 | NIMA-related kinase 7 | 0.0201915 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0200468 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.020022 |
| CLOCK | clock circadian regulator | 0.0199881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.144198 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.121541 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.113603 |
| RUNX1 | runt-related transcription factor 1 | -0.110369 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10724 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0938187 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0895216 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0857828 |
| LCN2 | lipocalin 2 | -0.082902 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0808671 |
| PERP | PERP, TP53 apoptosis effector | -0.0802676 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0778272 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0737255 |
| IRF1 | interferon regulatory factor 1 | -0.0717289 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0675068 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0671375 |
| PTMA | prothymosin, alpha | -0.0660404 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0652794 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0634218 |
| MSI2 | musashi RNA-binding protein 2 | -0.0626745 |
| HLA-B | major histocompatibility complex, class I, B | -0.062592 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.061943 |
| EGR1 | early growth response 1 | -0.0618954 |
| EFNB2 | ephrin-B2 | -0.0592707 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.058611 |
| EPHB2 | EPH receptor B2 | -0.0580383 |
| PRKCA | protein kinase C, alpha | -0.0579246 |
| TRERF1 | transcriptional regulating factor 1 | -0.0575435 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0567076 |
| CCNL1 | cyclin L1 | -0.0564843 |
| PKM | pyruvate kinase, muscle | -0.0562832 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0547545 |
| MX2 | MX dynamin-like GTPase 2 | -0.0539499 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0539068 |
| AGR2 | anterior gradient 2 | -0.0535134 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.052906 |
| ITGA6 | integrin, alpha 6 | -0.0511539 |
| H1-0 | H1.0 linker histone | -0.0505821 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.050431 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0498463 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.049464 |
| S100A10 | S100 calcium binding protein A10 | -0.0491857 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0489157 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0485251 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0468253 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0462222 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0461307 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0451336 |
| ABLIM1 | actin binding LIM protein 1 | -0.045083 |
| EHF | ets homologous factor | -0.0450617 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0450048 |
| ABHD2 | abhydrolase domain containing 2 | -0.0446711 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0446105 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.044414 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0435981 |
| ZNRF3 | zinc and ring finger 3 | -0.043534 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0435299 |
| MT2A | metallothionein 2A | -0.0435052 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0426544 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0423433 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0423422 |
| EZR | ezrin | -0.0421404 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0419009 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0418996 |
| PGK1 | phosphoglycerate kinase 1 | -0.0399781 |
| ATP11A | ATPase, class VI, type 11A | -0.0391125 |
| LYZ | lysozyme | -0.0384479 |
| UBC | ubiquitin C | -0.0377527 |
| FTL | ferritin, light polypeptide | -0.03747 |
| TFG | TRK-fused gene | -0.0374646 |
| XAF1 | XIAP associated factor 1 | -0.0373355 |
| CANX | calnexin | -0.0369138 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.036644 |
| TPM4 | tropomyosin 4 | -0.0358874 |
| FRYL | FRY-like | -0.0356599 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0356423 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0352146 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0348626 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0348543 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0342231 |
| NEBL | nebulette | -0.0339745 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0339718 |
| XPO1 | exportin 1 | -0.0334554 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0332728 |
| ANXA2 | annexin A2 | -0.032944 |
| ATXN1 | ataxin 1 | -0.0326196 |
| KRT19 | keratin 19, type I | -0.032514 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0324132 |
| FMN1 | formin 1 | -0.0322585 |
| HM13 | histocompatibility (minor) 13 | -0.0321807 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0319081 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0317636 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0316754 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313139 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0308723 |
| TMSB10 | thymosin beta 10 | -0.0307708 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0307681 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0305451 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0303802 |
| POTEF | POTE ankyrin domain family, member F | -0.0302371 |
