| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.135101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.113143 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0965018 |
| VIM | vimentin | 0.0803915 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0723835 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0669912 |
| STC1 | stanniocalcin 1 | 0.0588701 |
| ATP13A3 | ATPase type 13A3 | 0.0582431 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0459861 |
| MT1X | metallothionein 1X | 0.0449028 |
| CALR | calreticulin | 0.0442614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0442506 |
| CAVIN1 | caveolae associated protein 1 | 0.0442035 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0406324 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.03962 |
| LOX | lysyl oxidase | 0.0367383 |
| SQLE | squalene epoxidase | 0.0363886 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.035233 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0347311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0343513 |
| PTMA | prothymosin, alpha | 0.0338731 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0335341 |
| B2M | beta-2-microglobulin | 0.033428 |
| ANXA2 | annexin A2 | 0.033309 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0330143 |
| LDHA | lactate dehydrogenase A | 0.0327354 |
| KLF6 | Kruppel-like factor 6 | 0.0272765 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0271463 |
| RASA2 | RAS p21 protein activator 2 | 0.0271022 |
| POSTN | periostin, osteoblast specific factor | 0.0263898 |
| ARRDC3 | arrestin domain containing 3 | 0.0258223 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0256433 |
| TMSB4X | thymosin beta 4, X-linked | 0.0247055 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0246233 |
| TAGLN2 | transgelin 2 | 0.0237871 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.023672 |
| SMAD3 | SMAD family member 3 | 0.0231325 |
| USP3 | ubiquitin specific peptidase 3 | 0.0227785 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0210888 |
| SPAG9 | sperm associated antigen 9 | 0.0208687 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0205265 |
| MATR3 | matrin 3 | 0.0200662 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0197987 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0194054 |
| SRGN | serglycin | 0.0193317 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0191068 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0189781 |
| COL3A1 | collagen, type III, alpha 1 | 0.0188489 |
| SERINC1 | serine incorporator 1 | 0.0186282 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0185692 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0184569 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0181687 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.018126 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0180557 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0179814 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0178617 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0177955 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0173536 |
| DUSP6 | dual specificity phosphatase 6 | 0.0170364 |
| FNBP1L | formin binding protein 1-like | 0.0169417 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0165616 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0163718 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.016366 |
| ZNF292 | zinc finger protein 292 | 0.016308 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0160572 |
| HMGB2 | high mobility group box 2 | 0.0157527 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0157462 |
| RPLP0 | ribosomal protein, large, P0 | 0.015608 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0154622 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0153818 |
| GNAS | GNAS complex locus | 0.0150022 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0147199 |
| SERINC3 | serine incorporator 3 | 0.0146972 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0146363 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0146291 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0143718 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0139863 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0138861 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0138576 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0137909 |
| RACK1 | receptor for activated C kinase 1 | 0.0136878 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0136717 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0136573 |
| HAS2 | hyaluronan synthase 2 | 0.013591 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0135591 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0135489 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0130233 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0129155 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0128162 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0125894 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0124571 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0120996 |
| RPS3 | ribosomal protein S3 | 0.012079 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0118987 |
| RRBP1 | ribosome binding protein 1 | 0.0118775 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0118774 |
| TKT | transketolase | 0.0117496 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0117412 |
| MLF1 | myeloid leukemia factor 1 | 0.0116247 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0116059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.206696 |
| NDRG1 | N-myc downstream regulated 1 | -0.151913 |
| CDH13 | cadherin 13 | -0.145773 |
| COL6A3 | collagen, type VI, alpha 3 | -0.119719 |
| FNDC3B | fibronectin type III domain containing 3B | -0.110482 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0926193 |
| COL5A1 | collagen, type V, alpha 1 | -0.088724 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0803663 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0768287 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0695609 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0681006 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0669184 |
| CADM1 | cell adhesion molecule 1 | -0.0665139 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0637291 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0612382 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0611427 |
| COL1A1 | collagen, type I, alpha 1 | -0.060999 |
| FBN1 | fibrillin 1 | -0.0559139 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0521867 |
| GOLGB1 | golgin B1 | -0.0512566 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0509709 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.050494 |
| PRELID2 | PRELI domain containing 2 | -0.0497944 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0483735 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0468209 |
| GLIS3 | GLIS family zinc finger 3 | -0.0465369 |
| EGFR | epidermal growth factor receptor | -0.0463497 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0445174 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0444547 |
| ATXN1 | ataxin 1 | -0.0435932 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0435717 |
| CALD1 | caldesmon 1 | -0.0424994 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0416713 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0414703 |
| FN1 | fibronectin 1 | -0.0410396 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0406107 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.039864 |
| PDE10A | phosphodiesterase 10A | -0.0380195 |
| RUNX1 | runt-related transcription factor 1 | -0.0368848 |
| ASPH | aspartate beta-hydroxylase | -0.0368827 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0368556 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0367649 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.036449 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0362383 |
| CNTN5 | contactin 5 | -0.0361415 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0357622 |
| NAV1 | neuron navigator 1 | -0.0347719 |
| SMYD3 | SET and MYND domain containing 3 | -0.0345066 |
| FNIP1 | folliculin interacting protein 1 | -0.0340113 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0338864 |
| ACTG1 | actin gamma 1 | -0.0334059 |
| STC2 | stanniocalcin 2 | -0.0330351 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0323637 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0319341 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0315434 |
| DST | dystonin | -0.0309902 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0299877 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0299356 |
| AHNAK | AHNAK nucleoprotein | -0.0297468 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0294755 |
| VEGFA | vascular endothelial growth factor A | -0.029457 |
| HDAC9 | histone deacetylase 9 | -0.0294401 |
| CMIP | c-Maf inducing protein | -0.029118 |
| RPL35A | ribosomal protein L35a | -0.0289189 |
| CUX1 | cut-like homeobox 1 | -0.0288907 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0287932 |
| PLEC | plectin | -0.0286353 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0280634 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280186 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0277626 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0274718 |
| FTL | ferritin, light polypeptide | -0.0269626 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0265928 |
| VMP1 | vacuole membrane protein 1 | -0.0263559 |
| EXOC4 | exocyst complex component 4 | -0.025971 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0258472 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0256608 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.025103 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0245559 |
| TENM3 | teneurin transmembrane protein 3 | -0.0243949 |
| VCL | vinculin | -0.0243396 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0243161 |
| NABP1 | nucleic acid binding protein 1 | -0.0242975 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0240155 |
| MAP4 | microtubule-associated protein 4 | -0.0239818 |
| DGKI | diacylglycerol kinase, iota | -0.0238847 |
| RPS6 | ribosomal protein S6 | -0.0235018 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.023475 |
| EPHB1 | EPH receptor B1 | -0.0234624 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0234205 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0233717 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0233452 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0229201 |
| ZNF644 | zinc finger protein 644 | -0.0228278 |
| SQSTM1 | sequestosome 1 | -0.0228236 |
| VCAN | versican | -0.0228105 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0223048 |
| RAD51B | RAD51 paralog B | -0.0221625 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0219802 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.021633 |
