| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.158848 |
| PCBP2 | poly(rC) binding protein 2 | 0.0716678 |
| GOLGA4 | golgin A4 | 0.0555055 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0545433 |
| ATP13A3 | ATPase type 13A3 | 0.0454278 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0423955 |
| OGA | O-GlcNAcase | 0.0400761 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0379264 |
| SRP54 | signal recognition particle 54kDa | 0.0361128 |
| SMAD3 | SMAD family member 3 | 0.0360387 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0359776 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0352498 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0337383 |
| FAM13A | family with sequence similarity 13, member A | 0.0332997 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0329306 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0313641 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0312204 |
| RBM39 | RNA binding motif protein 39 | 0.0307643 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0302781 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0301908 |
| USP3 | ubiquitin specific peptidase 3 | 0.0298359 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0297638 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0293263 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0286492 |
| RNF145 | ring finger protein 145 | 0.0267116 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0266884 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.026476 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0262441 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0248558 |
| COG5 | component of oligomeric golgi complex 5 | 0.0247995 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.024666 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0243861 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.023915 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0236907 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0233667 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0230599 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.022917 |
| SBF2 | SET binding factor 2 | 0.0228449 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0225602 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0224751 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0223418 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0222238 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0221675 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0216576 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.02116 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0210724 |
| XPO1 | exportin 1 | 0.0208527 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0207307 |
| ARRDC3 | arrestin domain containing 3 | 0.0204406 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0204289 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0203517 |
| SPAG9 | sperm associated antigen 9 | 0.0197886 |
| RNF149 | ring finger protein 149 | 0.0196682 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.019619 |
| COPA | coatomer protein complex, subunit alpha | 0.0195533 |
| SLMAP | sarcolemma associated protein | 0.0195105 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0192775 |
| ADM | adrenomedullin | 0.0192381 |
| FOXO3 | forkhead box O3 | 0.0191618 |
| RBM25 | RNA binding motif protein 25 | 0.0189679 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0188734 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0187303 |
| THOC2 | THO complex 2 | 0.0187071 |
| NBAS | neuroblastoma amplified sequence | 0.0185507 |
| SIK3 | SIK family kinase 3 | 0.0184593 |
| ETNK1 | ethanolamine kinase 1 | 0.0184526 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.018386 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0182623 |
| CD109 | CD109 molecule | 0.018128 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0179455 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0179064 |
| YBX3 | Y box binding protein 3 | 0.0177331 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0176338 |
| TBK1 | TANK-binding kinase 1 | 0.0175945 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0175353 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0174925 |
| FRMD5 | FERM domain containing 5 | 0.0173269 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0172609 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0172174 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0171347 |
| MT2A | metallothionein 2A | 0.0170699 |
| FOXJ3 | forkhead box J3 | 0.0168994 |
| NGLY1 | N-glycanase 1 | 0.0168019 |
| YTHDC1 | YTH domain containing 1 | 0.016687 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.01664 |
| SUCO | SUN domain containing ossification factor | 0.0164332 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0163575 |
| RNF24 | ring finger protein 24 | 0.0160426 |
| PHIP | pleckstrin homology domain interacting protein | 0.0160079 |
| AHR | aryl hydrocarbon receptor | 0.0159884 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0158939 |
| YBX1 | Y box binding protein 1 | 0.0158586 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0158497 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0157173 |
| SNX13 | sorting nexin 13 | 0.0157102 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0157041 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0156625 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0156196 |
| POM121 | POM121 transmembrane nucleoporin | 0.015571 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0155654 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.251015 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.175506 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.165875 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.152404 |
| VIM | vimentin | -0.138207 |
| CDH13 | cadherin 13 | -0.135079 |
| HMGA2 | high mobility group AT-hook 2 | -0.121728 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.111913 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.10714 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103546 |
| DPYD | dihydropyrimidine dehydrogenase | -0.100662 |
| TMSB10 | thymosin beta 10 | -0.0976356 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0962006 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0932315 |
| NRG1 | neuregulin 1 | -0.0847638 |
| DST | dystonin | -0.0788216 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0775283 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0743036 |
| LOX | lysyl oxidase | -0.0729531 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0723093 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0694401 |
| MTSS1 | metastasis suppressor 1 | -0.0687904 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0645229 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0621283 |
| FAM20C | family with sequence similarity 20, member C | -0.0620051 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0612331 |
| MEF2A | myocyte enhancer factor 2A | -0.0608763 |
| RAI14 | retinoic acid induced 14 | -0.0607874 |
| GPC6 | glypican 6 | -0.0606589 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0603342 |
| ASPH | aspartate beta-hydroxylase | -0.059979 |
| GLCCI1 | glucocorticoid induced 1 | -0.0587394 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0571947 |
| ENO1 | enolase 1, (alpha) | -0.0565469 |
| CUX1 | cut-like homeobox 1 | -0.0562847 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0554447 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0546202 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0544857 |
| FBN1 | fibrillin 1 | -0.0541478 |
| AHNAK | AHNAK nucleoprotein | -0.0539943 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0505927 |
| RAD51B | RAD51 paralog B | -0.0504705 |
| SYT1 | synaptotagmin I | -0.0501203 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0485527 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.048454 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0480069 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0471895 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0467486 |
| OXR1 | oxidation resistance 1 | -0.046529 |
| ATXN1 | ataxin 1 | -0.0459284 |
| EFNA5 | ephrin-A5 | -0.0454646 |
| GLIS3 | GLIS family zinc finger 3 | -0.0443818 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0443192 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0442677 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.044023 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0433643 |
| NAV1 | neuron navigator 1 | -0.0431322 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0423564 |
| STC1 | stanniocalcin 1 | -0.0422955 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0421283 |
| SEPTIN9 | septin 9 | -0.0420981 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0418032 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0407483 |
| AADAC | arylacetamide deacetylase | -0.0405305 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397727 |
| ZNF804A | zinc finger protein 804A | -0.0397298 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0392729 |
| MECOM | MDS1 and EVI1 complex locus | -0.0388524 |
| S100A6 | S100 calcium binding protein A6 | -0.0385366 |
| CD44 | CD44 molecule (Indian blood group) | -0.0385288 |
| CDK14 | cyclin-dependent kinase 14 | -0.0381647 |
| PRKCA | protein kinase C, alpha | -0.0380527 |
| SUMF1 | sulfatase modifying factor 1 | -0.0380469 |
| RNF213 | ring finger protein 213 | -0.0379939 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.037952 |
| VCL | vinculin | -0.0376649 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0374363 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0373401 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0372854 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.037247 |
| CLMP | CXADR-like membrane protein | -0.0369781 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0368237 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0357034 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0355695 |
| SP100 | SP100 nuclear antigen | -0.0354424 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0354199 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0354142 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0351693 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0350844 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0348911 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0342791 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0341077 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0338115 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.033581 |
| IFI44L | interferon-induced protein 44-like | -0.0329561 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0329063 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0325748 |
| PTMA | prothymosin, alpha | -0.0323588 |
| PKM | pyruvate kinase, muscle | -0.0322251 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0321139 |
