| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.248558 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.150522 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0967859 |
| PCBP2 | poly(rC) binding protein 2 | 0.0949086 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0928781 |
| VEGFA | vascular endothelial growth factor A | 0.0827324 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0821981 |
| MSN | moesin | 0.0743318 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0734496 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.072769 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0703068 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0702655 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0687234 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0669448 |
| LDHA | lactate dehydrogenase A | 0.0596491 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0585081 |
| MYO6 | myosin VI | 0.0563432 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0544694 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0544091 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0540392 |
| RACK1 | receptor for activated C kinase 1 | 0.052508 |
| RBM25 | RNA binding motif protein 25 | 0.0522375 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0511311 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0506008 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0501578 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.04794 |
| HDGF | hepatoma-derived growth factor | 0.0451637 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0450716 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0448284 |
| RNF145 | ring finger protein 145 | 0.0437075 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0432627 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0423407 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0417126 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0415622 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0412805 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0402222 |
| CALR | calreticulin | 0.0398711 |
| RHOA | ras homolog family member A | 0.0395406 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0380205 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0374469 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0367129 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0354537 |
| RPS3 | ribosomal protein S3 | 0.0351684 |
| CCNL1 | cyclin L1 | 0.0347757 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0343801 |
| SFTPA2 | surfactant protein A2 | 0.0342246 |
| TMF1 | TATA element modulatory factor 1 | 0.034015 |
| TMEM165 | transmembrane protein 165 | 0.0339248 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0335927 |
| HLA-A | major histocompatibility complex, class I, A | 0.0335177 |
| DSTN | destrin (actin depolymerizing factor) | 0.0334502 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0323829 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0323733 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.032187 |
| WDR43 | WD repeat domain 43 | 0.031838 |
| PEG10 | paternally expressed 10 | 0.0316093 |
| PAPOLA | poly(A) polymerase alpha | 0.0315468 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0315306 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0312343 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0307273 |
| ZNF148 | zinc finger protein 148 | 0.0304976 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0304073 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0303166 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0302743 |
| MATR3 | matrin 3 | 0.030026 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0297804 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0297021 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0296734 |
| RPS12 | ribosomal protein S12 | 0.0295569 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0295402 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0294018 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.029147 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0290733 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0289387 |
| CLDN4 | claudin 4 | 0.0287956 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0287587 |
| AREG | amphiregulin | 0.0285687 |
| TPM3 | tropomyosin 3 | 0.0285403 |
| RCOR1 | REST corepressor 1 | 0.0285002 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0284189 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0283484 |
| ANXA1 | annexin A1 | 0.0282483 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0276189 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0274218 |
| TAGLN2 | transgelin 2 | 0.0270829 |
| EZR | ezrin | 0.0270699 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0270678 |
| SET | SET nuclear proto-oncogene | 0.0264094 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0262908 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0262346 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0258648 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0258615 |
| CD109 | CD109 molecule | 0.025735 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0255025 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.025358 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.025127 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0250921 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0248703 |
| MED13 | mediator complex subunit 13 | 0.0248397 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0245513 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.385996 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.238962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.178459 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.152356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.100625 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0955093 |
| RPL35A | ribosomal protein L35a | -0.0870829 |
| PTMA | prothymosin, alpha | -0.0785955 |
| AHNAK | AHNAK nucleoprotein | -0.0775884 |
| LMO7 | LIM domain 7 | -0.076331 |
| LAMC2 | laminin, gamma 2 | -0.0717906 |
| CANX | calnexin | -0.0687908 |
| S100A10 | S100 calcium binding protein A10 | -0.0679853 |
| RPL34 | ribosomal protein L34 | -0.0675352 |
| TMSB10 | thymosin beta 10 | -0.0667344 |
| ACTG1 | actin gamma 1 | -0.0645164 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0625918 |
| H1-0 | H1.0 linker histone | -0.0583985 |
| NDRG1 | N-myc downstream regulated 1 | -0.0558275 |
| CD2AP | CD2-associated protein | -0.0551727 |
| RPLP1 | ribosomal protein, large, P1 | -0.0500165 |
| NAV2 | neuron navigator 2 | -0.0497676 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0494365 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0488073 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0470647 |
| TMEM123 | transmembrane protein 123 | -0.0458222 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0455851 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0455115 |
| PGK1 | phosphoglycerate kinase 1 | -0.0418303 |
| LAMB3 | laminin, beta 3 | -0.0416238 |
| FHIT | fragile histidine triad | -0.0415729 |
| RPS24 | ribosomal protein S24 | -0.0395557 |
| RPS23 | ribosomal protein S23 | -0.0385427 |
| RPL32 | ribosomal protein L32 | -0.0348202 |
| ASPH | aspartate beta-hydroxylase | -0.0346454 |
| RPL8 | ribosomal protein L8 | -0.0338936 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0337605 |
| MX2 | MX dynamin-like GTPase 2 | -0.0335921 |
| RNF213 | ring finger protein 213 | -0.0334345 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0332423 |
| DSG2 | desmoglein 2 | -0.0331685 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0329912 |
| RPS13 | ribosomal protein S13 | -0.0324702 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0314377 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0309712 |
| RPS8 | ribosomal protein S8 | -0.0309634 |
| FAM162A | family with sequence similarity 162, member A | -0.0308911 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0300712 |
| RPL28 | ribosomal protein L28 | -0.0297256 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0295311 |
| S100A6 | S100 calcium binding protein A6 | -0.0291692 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0290036 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0288152 |
| STEAP4 | STEAP family member 4 | -0.0283435 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0280302 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0278893 |
| ANXA2 | annexin A2 | -0.027837 |
| UPP1 | uridine phosphorylase 1 | -0.0275833 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0268855 |
| SP100 | SP100 nuclear antigen | -0.0266127 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0265284 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0264653 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0263927 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0262686 |
| RPLP0 | ribosomal protein, large, P0 | -0.0255021 |
| RPLP2 | ribosomal protein, large, P2 | -0.0252264 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0251394 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0249621 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0249409 |
| KRT8 | keratin 8, type II | -0.0248536 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0248296 |
| HDLBP | high density lipoprotein binding protein | -0.0248075 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0247152 |
| SDC4 | syndecan 4 | -0.0246982 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0246662 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.024519 |
| G0S2 | G0/G1 switch 2 | -0.0243083 |
| RPL12 | ribosomal protein L12 | -0.024262 |
| HMGB1 | high mobility group box 1 | -0.023852 |
| RPS27A | ribosomal protein S27a | -0.0235985 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0234518 |
| RPL19 | ribosomal protein L19 | -0.0231181 |
| IER3 | immediate early response 3 | -0.0227634 |
| ARF1 | ADP-ribosylation factor 1 | -0.0221179 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0218099 |
| HMGA1 | high mobility group AT-hook 1 | -0.0217918 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0217844 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0217324 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0214562 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0213261 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0211344 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0211246 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0210756 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0209697 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0206404 |
| RPS25 | ribosomal protein S25 | -0.0205913 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0205416 |
| RPS10 | ribosomal protein S10 | -0.0203441 |
| TXNRD1 | thioredoxin reductase 1 | -0.0203269 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0202752 |
