| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.136167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.135712 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.131055 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.121888 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.119979 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.110824 |
| PEG10 | paternally expressed 10 | 0.0962671 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.090193 |
| CENPF | centromere protein F, 350/400kDa | 0.0822613 |
| TMSB4X | thymosin beta 4, X-linked | 0.0806715 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0754 |
| POTEF | POTE ankyrin domain family, member F | 0.0744354 |
| TSC22D2 | TSC22 domain family, member 2 | 0.074179 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0673291 |
| MKI67 | marker of proliferation Ki-67 | 0.0649621 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0646347 |
| WDR43 | WD repeat domain 43 | 0.0601167 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.0593695 |
| ITGAV | integrin, alpha V | 0.0590989 |
| THBS1 | thrombospondin 1 | 0.0579315 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0576111 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0571 |
| TPX2 | TPX2, microtubule-associated | 0.0543507 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0529137 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0526045 |
| PTMA | prothymosin, alpha | 0.0523831 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0514224 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0495063 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0479941 |
| PCBP2 | poly(rC) binding protein 2 | 0.0477305 |
| PFN1 | profilin 1 | 0.0472664 |
| STAG2 | stromal antigen 2 | 0.0471798 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0468685 |
| ZFR | zinc finger RNA binding protein | 0.0466555 |
| HMGB2 | high mobility group box 2 | 0.0458232 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0457877 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0457445 |
| NRG1 | neuregulin 1 | 0.045379 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0450904 |
| RBM25 | RNA binding motif protein 25 | 0.0444329 |
| COL3A1 | collagen, type III, alpha 1 | 0.0442386 |
| MATR3 | matrin 3 | 0.0439698 |
| COL5A2 | collagen, type V, alpha 2 | 0.0438915 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0429382 |
| MTF2 | metal response element binding transcription factor 2 | 0.0416778 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0414385 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0414198 |
| KIF5B | kinesin family member 5B | 0.0410625 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0406543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0404674 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0404186 |
| CALR | calreticulin | 0.0394919 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0389911 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0389224 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0388297 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0386616 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0380706 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0377875 |
| ACTN4 | actinin, alpha 4 | 0.037575 |
| RTN4 | reticulon 4 | 0.036786 |
| RHEB | Ras homolog enriched in brain | 0.0366104 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0364165 |
| NOP58 | NOP58 ribonucleoprotein | 0.036261 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0361047 |
| USP3 | ubiquitin specific peptidase 3 | 0.0360401 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0359262 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0355966 |
| ANXA1 | annexin A1 | 0.0355314 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0352982 |
| METAP2 | methionyl aminopeptidase 2 | 0.0349257 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0338389 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0338122 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0337795 |
| NCKAP1 | NCK-associated protein 1 | 0.0335975 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0335621 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0335246 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0334941 |
| ECT2 | epithelial cell transforming 2 | 0.0334754 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.033403 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0332054 |
| THOC2 | THO complex 2 | 0.0331959 |
| RLF | rearranged L-myc fusion | 0.0331656 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0329236 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0328702 |
| CRY1 | cryptochrome circadian clock 1 | 0.0327685 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0327637 |
| CCN2 | cellular communication network factor 2 | 0.0326545 |
| H1-0 | H1.0 linker histone | 0.0325425 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0324807 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0319363 |
| RIOK3 | RIO kinase 3 | 0.0317893 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0316074 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0314746 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0312662 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0312208 |
| EMP1 | epithelial membrane protein 1 | 0.0310092 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0307047 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0305296 |
| ZNF292 | zinc finger protein 292 | 0.0305025 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.030387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.144432 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0932252 |
| CADM2 | cell adhesion molecule 2 | -0.0789633 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0704334 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0678506 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0656198 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0589249 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0577244 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0568117 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.056356 |
| RASAL2 | RAS protein activator like 2 | -0.0563373 |
| SCFD1 | sec1 family domain containing 1 | -0.054735 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.054057 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0538138 |
| HDAC9 | histone deacetylase 9 | -0.0520368 |
| NEBL | nebulette | -0.0519335 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.051811 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0496268 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0495225 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0486877 |
| INTS6 | integrator complex subunit 6 | -0.0477544 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0474766 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0455144 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.045057 |
| CEP350 | centrosomal protein 350kDa | -0.0426432 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0418852 |
| USP25 | ubiquitin specific peptidase 25 | -0.0409225 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0403826 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0400862 |
| LPIN2 | lipin 2 | -0.0400835 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0397265 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0395062 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0388922 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0388515 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0385181 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0384742 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0383923 |
| LYST | lysosomal trafficking regulator | -0.0382953 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0375556 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0372615 |
| PRKD1 | protein kinase D1 | -0.0363037 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0363016 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0362772 |
| SPAG9 | sperm associated antigen 9 | -0.0362427 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0361391 |
| SRP54 | signal recognition particle 54kDa | -0.0356599 |
| RCOR1 | REST corepressor 1 | -0.0351966 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0343548 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0338861 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0338574 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0338148 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.033429 |
| LDHA | lactate dehydrogenase A | -0.0332301 |
| ATXN1 | ataxin 1 | -0.0327989 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0324103 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0317599 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0308072 |
| TENM3 | teneurin transmembrane protein 3 | -0.0307696 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0305766 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0304818 |
| SYT1 | synaptotagmin I | -0.0300422 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0299711 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0299331 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0298866 |
| FGF13 | fibroblast growth factor 13 | -0.029562 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0295259 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0292696 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0292216 |
| SIK2 | salt-inducible kinase 2 | -0.0289708 |
| LRRC4C | leucine rich repeat containing 4C | -0.0289625 |
| WWC2 | WW and C2 domain containing 2 | -0.028932 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0286971 |
| UTRN | utrophin | -0.0285933 |
| NHSL1 | NHS-like 1 | -0.0284977 |
| FRYL | FRY-like | -0.0283676 |
| RBM20 | RNA binding motif protein 20 | -0.0280928 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0278611 |
| USP53 | ubiquitin specific peptidase 53 | -0.0276956 |
| TRIM2 | tripartite motif containing 2 | -0.0275738 |
| HM13 | histocompatibility (minor) 13 | -0.0275288 |
| NXN | nucleoredoxin | -0.0274522 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0272326 |
| NRXN1 | neurexin 1 | -0.0266038 |
| DENND5B | DENN/MADD domain containing 5B | -0.0264962 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.026426 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0264147 |
| SMYD3 | SET and MYND domain containing 3 | -0.0263705 |
| PCDH17 | protocadherin 17 | -0.0262907 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0260649 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0260516 |
| GOLGB1 | golgin B1 | -0.0260362 |
| UBE3C | ubiquitin protein ligase E3C | -0.0260295 |
| NBEAL1 | neurobeachin-like 1 | -0.0257874 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0256157 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0253365 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0252715 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0252658 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.025234 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0251664 |
| ERBIN | erbb2 interacting protein | -0.0250716 |
