| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.193916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.126171 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.106291 |
| WTAP | Wilms tumor 1 associated protein | 0.10437 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.103966 |
| HLA-A | major histocompatibility complex, class I, A | 0.101346 |
| POTEF | POTE ankyrin domain family, member F | 0.0783762 |
| TMSB10 | thymosin beta 10 | 0.0737547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0717867 |
| HLA-B | major histocompatibility complex, class I, B | 0.0703877 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0623072 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0582538 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0534691 |
| MATR3 | matrin 3 | 0.0525613 |
| CDC73 | cell division cycle 73 | 0.0516391 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0516171 |
| SETD5 | SET domain containing 5 | 0.0497805 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0497213 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0471764 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0462997 |
| RND3 | Rho family GTPase 3 | 0.0436425 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0430005 |
| RPL11 | ribosomal protein L11 | 0.0428483 |
| QKI | QKI, KH domain containing, RNA binding | 0.0424038 |
| RPL31 | ribosomal protein L31 | 0.0414363 |
| S100A10 | S100 calcium binding protein A10 | 0.041319 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0412889 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.040497 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0402515 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0392917 |
| FTL | ferritin, light polypeptide | 0.0378185 |
| UBC | ubiquitin C | 0.037783 |
| S100A6 | S100 calcium binding protein A6 | 0.0369639 |
| RNF145 | ring finger protein 145 | 0.0369027 |
| PFN1 | profilin 1 | 0.036523 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0360169 |
| MORF4L1 | mortality factor 4 like 1 | 0.0359412 |
| NOP58 | NOP58 ribonucleoprotein | 0.0359371 |
| PTMA | prothymosin, alpha | 0.0349498 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0349042 |
| FNDC3A | fibronectin type III domain containing 3A | 0.034698 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0343565 |
| ITM2B | integral membrane protein 2B | 0.0333303 |
| NUP58 | nucleoporin 58 | 0.0331168 |
| SPAG9 | sperm associated antigen 9 | 0.0330928 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0329871 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0329871 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0329447 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0326371 |
| RBM39 | RNA binding motif protein 39 | 0.0323439 |
| RIOK3 | RIO kinase 3 | 0.0322355 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0320898 |
| SNX9 | sorting nexin 9 | 0.0316774 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.031514 |
| ANXA5 | annexin A5 | 0.0309282 |
| RHEB | Ras homolog enriched in brain | 0.0304656 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0301412 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0296014 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0294003 |
| PRRC1 | proline-rich coiled-coil 1 | 0.029288 |
| NMD3 | NMD3 ribosome export adaptor | 0.0289848 |
| TMEM165 | transmembrane protein 165 | 0.0288703 |
| RPL23 | ribosomal protein L23 | 0.0286961 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0286714 |
| TMEM123 | transmembrane protein 123 | 0.0286265 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.02827 |
| DENND4C | DENN/MADD domain containing 4C | 0.0281735 |
| RPS3 | ribosomal protein S3 | 0.0280904 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0279497 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0278171 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0277514 |
| CLU | clusterin | 0.0277095 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0276467 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0275923 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0274529 |
| SFTPA2 | surfactant protein A2 | 0.0274401 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0273085 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0272342 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0271177 |
| RPS6 | ribosomal protein S6 | 0.0271101 |
| MTF2 | metal response element binding transcription factor 2 | 0.026977 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.0269497 |
| VMP1 | vacuole membrane protein 1 | 0.0268551 |
| TFG | TRK-fused gene | 0.0267437 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0266777 |
| COG5 | component of oligomeric golgi complex 5 | 0.0266654 |
| RPL9 | ribosomal protein L9 | 0.0266164 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0262473 |
| RPL36 | ribosomal protein L36 | 0.026173 |
| SMAD4 | SMAD family member 4 | 0.0261625 |
| RPL28 | ribosomal protein L28 | 0.0259232 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0258911 |
| RPL12 | ribosomal protein L12 | 0.0258835 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0254787 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0254233 |
| GOLGA4 | golgin A4 | 0.0253913 |
| XPO1 | exportin 1 | 0.0253652 |
| CTSD | cathepsin D | 0.0253565 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.025336 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0253013 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.240345 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.182781 |
| NRXN3 | neurexin 3 | -0.0991095 |
| CALD1 | caldesmon 1 | -0.0841879 |
| AHNAK | AHNAK nucleoprotein | -0.07875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0764105 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0729554 |
| CDK6 | cyclin-dependent kinase 6 | -0.071046 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0697671 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.069455 |
| LOX | lysyl oxidase | -0.0690933 |
| GLIS3 | GLIS family zinc finger 3 | -0.0685801 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0685469 |
| ANKRD17 | ankyrin repeat domain 17 | -0.067528 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0658229 |
| ATXN1 | ataxin 1 | -0.0642357 |
| ENO1 | enolase 1, (alpha) | -0.0633563 |
| EFNA5 | ephrin-A5 | -0.0629942 |
| FAM13A | family with sequence similarity 13, member A | -0.0626268 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0620829 |
| RAD51B | RAD51 paralog B | -0.0604453 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0587021 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0579913 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0577155 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0572766 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0567839 |
| CALU | calumenin | -0.0557335 |
| COL1A1 | collagen, type I, alpha 1 | -0.0555015 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0549744 |
| NDRG1 | N-myc downstream regulated 1 | -0.0534093 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.052909 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0520835 |
| EXOC4 | exocyst complex component 4 | -0.050735 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0505829 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.048164 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0473035 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0464394 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0462806 |
| CADM1 | cell adhesion molecule 1 | -0.0459215 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.04587 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.045806 |
| CDH13 | cadherin 13 | -0.0442526 |
| TNS3 | tensin 3 | -0.0441762 |
| VCL | vinculin | -0.0436685 |
| DST | dystonin | -0.0436605 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0431219 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0426246 |
| KAZN | kazrin, periplakin interacting protein | -0.0417936 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0415739 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0413493 |
| COL5A1 | collagen, type V, alpha 1 | -0.0408174 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0405943 |
| TPM4 | tropomyosin 4 | -0.039229 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0386499 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0382583 |
| CD44 | CD44 molecule (Indian blood group) | -0.0380976 |
| FRMD4A | FERM domain containing 4A | -0.037988 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0373164 |
| HIP1 | huntingtin interacting protein 1 | -0.0372036 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0371218 |
| NAV1 | neuron navigator 1 | -0.0368331 |
| STC1 | stanniocalcin 1 | -0.0368179 |
| GSE1 | Gse1 coiled-coil protein | -0.0364406 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0359848 |
| CD99 | CD99 molecule | -0.03561 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0347728 |
| PDE10A | phosphodiesterase 10A | -0.0343874 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0341044 |
| SMYD3 | SET and MYND domain containing 3 | -0.0338955 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0335997 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0333357 |
| RUNX1 | runt-related transcription factor 1 | -0.0330194 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0328072 |
| ARF4 | ADP-ribosylation factor 4 | -0.0327791 |
| SMAD3 | SMAD family member 3 | -0.0323281 |
| MYO9A | myosin IXA | -0.0321566 |
| LMNA | lamin A/C | -0.0318983 |
| STC2 | stanniocalcin 2 | -0.0318845 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0313225 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0311438 |
| ANO6 | anoctamin 6 | -0.0307364 |
| SNX29 | sorting nexin 29 | -0.0305804 |
| TXNIP | thioredoxin interacting protein | -0.0305213 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0304961 |
| FHIT | fragile histidine triad | -0.030407 |
| ANXA2 | annexin A2 | -0.0299752 |
| RRBP1 | ribosome binding protein 1 | -0.0296929 |
| MT2A | metallothionein 2A | -0.0296825 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0296138 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0295993 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0290982 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0290873 |
| EGFR | epidermal growth factor receptor | -0.0287516 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0285141 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0282372 |
| CUX1 | cut-like homeobox 1 | -0.0282023 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0278708 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0278389 |
| ACTG1 | actin gamma 1 | -0.0277603 |
| COG6 | component of oligomeric golgi complex 6 | -0.0276143 |
