| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.272021 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.106332 |
| VIM | vimentin | 0.100091 |
| PTMA | prothymosin, alpha | 0.0866071 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0791991 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0702452 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0649467 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0586854 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0582995 |
| FTL | ferritin, light polypeptide | 0.0573039 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0560709 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0508642 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0472916 |
| POTEF | POTE ankyrin domain family, member F | 0.046246 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0449638 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0446029 |
| RPS3 | ribosomal protein S3 | 0.0438743 |
| TPX2 | TPX2, microtubule-associated | 0.0436592 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0428004 |
| DTNA | dystrobrevin, alpha | 0.042498 |
| TXNRD1 | thioredoxin reductase 1 | 0.0415521 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0413942 |
| ANXA1 | annexin A1 | 0.0397414 |
| YBX3 | Y box binding protein 3 | 0.0385371 |
| NUP58 | nucleoporin 58 | 0.0385183 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0379725 |
| RPL23 | ribosomal protein L23 | 0.0378624 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0376026 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.03706 |
| CBX3 | chromobox homolog 3 | 0.0359241 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.035605 |
| USP3 | ubiquitin specific peptidase 3 | 0.0352812 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0351779 |
| NGLY1 | N-glycanase 1 | 0.0349898 |
| RPLP2 | ribosomal protein, large, P2 | 0.0344092 |
| TMEM41B | transmembrane protein 41B | 0.0343036 |
| TPI1 | triosephosphate isomerase 1 | 0.0338307 |
| TOP1 | topoisomerase (DNA) I | 0.033284 |
| RACK1 | receptor for activated C kinase 1 | 0.0332704 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0324292 |
| CALR | calreticulin | 0.0319517 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0317061 |
| NPTN | neuroplastin | 0.0315668 |
| RTN4 | reticulon 4 | 0.0315401 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0312082 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0311601 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0309437 |
| HJURP | Holliday junction recognition protein | 0.0302016 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0300745 |
| TAGLN2 | transgelin 2 | 0.0299829 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0297829 |
| SETD5 | SET domain containing 5 | 0.0296711 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.029645 |
| SQSTM1 | sequestosome 1 | 0.0295864 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0295542 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0295165 |
| RPL32 | ribosomal protein L32 | 0.0292995 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0291268 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0288823 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0287747 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0287666 |
| B2M | beta-2-microglobulin | 0.0285059 |
| RPLP1 | ribosomal protein, large, P1 | 0.0282781 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0280608 |
| ADM | adrenomedullin | 0.0278046 |
| RPS21 | ribosomal protein S21 | 0.0277239 |
| MORF4L2 | mortality factor 4 like 2 | 0.0277163 |
| NOP58 | NOP58 ribonucleoprotein | 0.0276836 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0271836 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0270207 |
| MYLIP | myosin regulatory light chain interacting protein | 0.0266951 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0266388 |
| WDR43 | WD repeat domain 43 | 0.0265614 |
| RCOR1 | REST corepressor 1 | 0.026519 |
| KIF5B | kinesin family member 5B | 0.0264128 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0263696 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0263324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0262528 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0261758 |
| GOLGA4 | golgin A4 | 0.0261435 |
| QKI | QKI, KH domain containing, RNA binding | 0.0259376 |
| TUBA1B | tubulin, alpha 1b | 0.0258814 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0257585 |
| RPL12 | ribosomal protein L12 | 0.0257248 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0256946 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0255271 |
| RAB10 | RAB10, member RAS oncogene family | 0.0255112 |
| CRY1 | cryptochrome circadian clock 1 | 0.0254418 |
| FOXO3 | forkhead box O3 | 0.0253219 |
| RPS17 | ribosomal protein S17 | 0.0252477 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0252139 |
| SPAG9 | sperm associated antigen 9 | 0.0250112 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.024885 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0248532 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0244994 |
| INSIG1 | insulin induced gene 1 | 0.024499 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0243408 |
| RPL15 | ribosomal protein L15 | 0.0243273 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0243195 |
| MKI67 | marker of proliferation Ki-67 | 0.0243173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | -0.103471 |
| RORA | RAR-related orphan receptor A | -0.0637399 |
| RAD51B | RAD51 paralog B | -0.0628067 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0606807 |
| OSMR | oncostatin M receptor | -0.0582867 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0481728 |
| HMGA2 | high mobility group AT-hook 2 | -0.0473176 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0460849 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0459557 |
| AHNAK | AHNAK nucleoprotein | -0.0429545 |
| FMNL2 | formin-like 2 | -0.0421701 |
| ANO6 | anoctamin 6 | -0.0417219 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0415119 |
| ATM | ATM serine/threonine kinase | -0.041491 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0410655 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0409584 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0408892 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0404269 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0403178 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0396231 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0392459 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.037884 |
| HDAC9 | histone deacetylase 9 | -0.0373965 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0368921 |
| CD44 | CD44 molecule (Indian blood group) | -0.0366654 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0363813 |
| LRRC49 | leucine rich repeat containing 49 | -0.0359796 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0350839 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0350501 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0348695 |
| USP34 | ubiquitin specific peptidase 34 | -0.0344312 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0343805 |
| SVIL | supervillin | -0.0342956 |
| BPTF | bromodomain PHD finger transcription factor | -0.0337751 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0336057 |
| SMAD3 | SMAD family member 3 | -0.0328981 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0327122 |
| PTK2 | protein tyrosine kinase 2 | -0.0325214 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0320075 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0314938 |
| CENPP | centromere protein P | -0.0314773 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0313881 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0313099 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.03087 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0303823 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.030359 |
| RANBP17 | RAN binding protein 17 | -0.0303464 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0292645 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.028831 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0287769 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0286935 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0286826 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0286485 |
| FMN1 | formin 1 | -0.0282748 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0280113 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0275835 |
| EFNA5 | ephrin-A5 | -0.0275143 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0275046 |
| EXOC4 | exocyst complex component 4 | -0.0273801 |
| GPATCH8 | G patch domain containing 8 | -0.0273367 |
| MYO9A | myosin IXA | -0.0273132 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0270765 |
| SDC4 | syndecan 4 | -0.0270225 |
| PRELID2 | PRELI domain containing 2 | -0.0269151 |
| TLK1 | tousled-like kinase 1 | -0.0268998 |
| VCL | vinculin | -0.0263688 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0262911 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0262357 |
| AEBP2 | AE binding protein 2 | -0.0258421 |
| HLA-C | major histocompatibility complex, class I, C | -0.0255962 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0251846 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0251691 |
| PHF3 | PHD finger protein 3 | -0.0251336 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0250857 |
| COMMD10 | COMM domain containing 10 | -0.0247201 |
| RNF213 | ring finger protein 213 | -0.0243236 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.024285 |
| ATG7 | autophagy related 7 | -0.0242569 |
| SYCP2 | synaptonemal complex protein 2 | -0.0241718 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0240953 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0240291 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0239502 |
| RAI14 | retinoic acid induced 14 | -0.0238958 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0238751 |
| FAF2 | Fas associated factor family member 2 | -0.0237151 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0236291 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0235342 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0234618 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0232775 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0231872 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.023098 |
| DIDO1 | death inducer-obliterator 1 | -0.0228662 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0226164 |
| ZNF721 | zinc finger protein 721 | -0.0225664 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0225626 |
| UTRN | utrophin | -0.0225623 |
| KIAA1328 | KIAA1328 | -0.0224855 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0224009 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0223178 |
| PCNX2 | pecanex 2 | -0.0221404 |
