| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Auranofin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Auranofin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.078014 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0649035 |
| ETNK1 | ethanolamine kinase 1 | 0.0510103 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0465666 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0424895 |
| SFTPA2 | surfactant protein A2 | 0.0370866 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0366129 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0347217 |
| B2M | beta-2-microglobulin | 0.0335177 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0325372 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0311929 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0290485 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0285868 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0275234 |
| SMOX | spermine oxidase | 0.0274344 |
| RBM25 | RNA binding motif protein 25 | 0.0272787 |
| SMAD3 | SMAD family member 3 | 0.0254152 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0242286 |
| RPL31 | ribosomal protein L31 | 0.0236571 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0229799 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0228899 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0227184 |
| EREG | epiregulin | 0.0225962 |
| CAB39 | calcium binding protein 39 | 0.0224506 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0223619 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0220561 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0219175 |
| COG5 | component of oligomeric golgi complex 5 | 0.0214867 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0214319 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0210396 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0208704 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0203456 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0202278 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0200343 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0196936 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.0193101 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0192033 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0191785 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0189779 |
| SETD2 | SET domain containing 2 | 0.0185672 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.0184005 |
| VCL | vinculin | 0.0182404 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0180726 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0180552 |
| RPL18 | ribosomal protein L18 | 0.0178216 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0177592 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0176605 |
| SUCO | SUN domain containing ossification factor | 0.0174307 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0170134 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0170093 |
| MT2A | metallothionein 2A | 0.0169976 |
| SERINC1 | serine incorporator 1 | 0.0169732 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0167911 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0167586 |
| TMF1 | TATA element modulatory factor 1 | 0.0167074 |
| GPATCH8 | G patch domain containing 8 | 0.0166814 |
| ZNF638 | zinc finger protein 638 | 0.0165858 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0165599 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0164736 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0164086 |
| TMEM263 | transmembrane protein 263 | 0.0162141 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0161759 |
| MED6 | mediator complex subunit 6 | 0.0159305 |
| ZNF146 | zinc finger protein 146 | 0.0159279 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0159258 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0157882 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0157474 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0157152 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0156406 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0155095 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0154429 |
| IPMK | inositol polyphosphate multikinase | 0.0151468 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0151368 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0150463 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0148642 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0148208 |
| TMEM165 | transmembrane protein 165 | 0.0147534 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0146452 |
| RPL11 | ribosomal protein L11 | 0.0146452 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0146081 |
| USP53 | ubiquitin specific peptidase 53 | 0.014562 |
| RNF115 | ring finger protein 115 | 0.0145507 |
| CD63 | CD63 molecule | 0.0145374 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0144926 |
| RAB18 | RAB18, member RAS oncogene family | 0.0144659 |
| RPL38 | ribosomal protein L38 | 0.0144486 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0144455 |
| LEMD3 | LEM domain containing 3 | 0.0142919 |
| TMEM39A | transmembrane protein 39A | 0.0142202 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.0140362 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0140334 |
| ATP5MK | ATP synthase membrane subunit k | 0.0140328 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0140003 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0139761 |
| CDC73 | cell division cycle 73 | 0.0139078 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.013841 |
| RNF169 | ring finger protein 169 | 0.0136946 |
| YLPM1 | YLP motif containing 1 | 0.013661 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0136388 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0136378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.310736 |
| FN1 | fibronectin 1 | -0.207153 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.184048 |
| NDRG1 | N-myc downstream regulated 1 | -0.157575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.148611 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.125722 |
| NRG1 | neuregulin 1 | -0.113657 |
| ASPH | aspartate beta-hydroxylase | -0.0985509 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0977383 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0967885 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0921145 |
| HMGA2 | high mobility group AT-hook 2 | -0.0873996 |
| VIM | vimentin | -0.0872356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0859331 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0859185 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0756221 |
| MAP1B | microtubule-associated protein 1B | -0.0730077 |
| CANX | calnexin | -0.0720287 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0717223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0707486 |
| PTK2 | protein tyrosine kinase 2 | -0.069744 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0677824 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0667879 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0656172 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0650804 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0640157 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0630303 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0605931 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0593636 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0588697 |
| RTN4 | reticulon 4 | -0.0579048 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0571712 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0558372 |
| UBC | ubiquitin C | -0.0533313 |
| STC2 | stanniocalcin 2 | -0.0531047 |
| TXNRD1 | thioredoxin reductase 1 | -0.0526002 |
| HMGA1 | high mobility group AT-hook 1 | -0.0521893 |
| FTL | ferritin, light polypeptide | -0.0507552 |
| SYT1 | synaptotagmin I | -0.0493613 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0486892 |
| CD109 | CD109 molecule | -0.0479082 |
| S100A6 | S100 calcium binding protein A6 | -0.0478398 |
| PKM | pyruvate kinase, muscle | -0.0472352 |
| PLIN2 | perilipin 2 | -0.0465341 |
| POTEF | POTE ankyrin domain family, member F | -0.0461542 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0458183 |
| DST | dystonin | -0.0443336 |
| RPS6 | ribosomal protein S6 | -0.0432181 |
| EZR | ezrin | -0.0431489 |
| MYOF | myoferlin | -0.0430574 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0424512 |
| SPAG9 | sperm associated antigen 9 | -0.0417552 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0417522 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0415862 |
| EGR1 | early growth response 1 | -0.0409261 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0408295 |
| RNF213 | ring finger protein 213 | -0.0404769 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0401611 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0397409 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0395436 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0394428 |
| SEPTIN7 | septin 7 | -0.038952 |
| TXNIP | thioredoxin interacting protein | -0.0379165 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0377934 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0377513 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0371961 |
| LMNA | lamin A/C | -0.0369615 |
| S100A10 | S100 calcium binding protein A10 | -0.0366124 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0365629 |
| PCBP2 | poly(rC) binding protein 2 | -0.0360448 |
| ACTG1 | actin gamma 1 | -0.0359238 |
| IL6 | interleukin 6 | -0.0359195 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0359086 |
| FAM13A | family with sequence similarity 13, member A | -0.0352064 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0352005 |
| FOSL1 | FOS-like antigen 1 | -0.0348959 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0347615 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0347288 |
| TPM3 | tropomyosin 3 | -0.0345003 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0343788 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0343538 |
| ACTN4 | actinin, alpha 4 | -0.0343393 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0340724 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0338228 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0336587 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0336239 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0334298 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0333702 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0333299 |
| ANXA2 | annexin A2 | -0.0329682 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0327477 |
| PARD3 | par-3 family cell polarity regulator | -0.0327437 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0322808 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0321679 |
| IL6ST | interleukin 6 signal transducer | -0.0321094 |
| PFN1 | profilin 1 | -0.0319716 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0319682 |
| ENO1 | enolase 1, (alpha) | -0.031815 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0318105 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0316271 |
