Autoinflammatory Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3267073
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Genes

80 genes associated with the disease Autoinflammatory Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ADA2 adenosine deaminase 2
ATN1 atrophin 1
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
CAPS calcyphosine
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CGAS cyclic GMP-AMP synthase
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DICER1 dicer 1, ribonuclease type III
DNASE2 deoxyribonuclease II, lysosomal
DPP9 dipeptidyl-peptidase 9
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPHB1 EPH receptor B1
ERAP1 endoplasmic reticulum aminopeptidase 1
FOXP3 forkhead box P3
GLI3 GLI family zinc finger 3
GSDMD gasdermin D
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL36R interleukin 36 receptor
IL36RN interleukin 36 receptor antagonist
IL6 interleukin 6
IRAK4 interleukin-1 receptor-associated kinase 4
ISG15 ISG15 ubiquitin-like modifier
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
LRP1 low density lipoprotein receptor-related protein 1
MDK midkine (neurite growth-promoting factor 2)
MEFV Mediterranean fever
MVK mevalonate kinase
MYD88 myeloid differentiation primary response 88
NDFIP1 Nedd4 family interacting protein 1
NECTIN1 nectin cell adhesion molecule 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRC3 NLR family, CARD domain containing 3
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NR1I2 nuclear receptor subfamily 1, group I, member 2
OTULIN OTU deubiquitinase with linear linkage specificity
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRLR prolactin receptor
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PYCARD PYD and CARD domain containing
RAB6A RAB6A, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF31 ring finger protein 31
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLPI secretory leukocyte peptidase inhibitor
STIM1 stromal interaction molecule 1
STING1 stimulator of interferon response cGAMP interactor 1
STS steroid sulfatase (microsomal), isozyme S
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR1 WD repeat domain 1