Axon Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. (Gene Ontology, GO_0030424)
External Link http://amigo.geneontology.org/amigo/term/GO:0030424
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Genes

339 proteins localized to the Axon cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ERMN ermin, ERM-like protein 5.0
CABP4 calcium binding protein 4 5.0
LRRTM1 leucine rich repeat transmembrane neuronal 1 5.0
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 5.0
BASP1 brain abundant, membrane attached signal protein 1 5.0
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5.0
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 5.0
DST dystonin 5.0
SETX senataxin 5.0
NCOA3 nuclear receptor coactivator 3 5.0
SPAST spastin 5.0
C4A complement component 4A (Rodgers blood group) 5.0
GHRL ghrelin/obestatin prepropeptide 5.0
CCSAP centriole, cilia and spindle-associated protein 5.0
NEFL neurofilament, light polypeptide 5.0
OTX2 orthodenticle homeobox 2 5.0
CLASP2 cytoplasmic linker associated protein 2 5.0
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 5.0
ZC3H14 zinc finger CCCH-type containing 14 5.0
AZIN2 antizyme inhibitor 2 5.0
ZNF804A zinc finger protein 804A 5.0
KIF21A kinesin family member 21A 5.0
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 5.0
USP9X ubiquitin specific peptidase 9, X-linked 5.0
PSEN1 presenilin 1 5.0
MYO5A myosin VA (heavy chain 12, myoxin) 5.0
KIF13B kinesin family member 13B 5.0
STMN2 stathmin 2 5.0
PPT1 palmitoyl-protein thioesterase 1 5.0
GARS1 glycyl-tRNA synthetase 1 5.0
COPA coatomer protein complex, subunit alpha 5.0
OPRM1 opioid receptor, mu 1 4.0
EPHB2 EPH receptor B2 4.0
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 4.0
STAT1 signal transducer and activator of transcription 1, 91kDa 4.0
MYO9A myosin IXA 4.0
FKBP4 FK506 binding protein 4, 59kDa 4.0
TENM2 teneurin transmembrane protein 2 4.0
DSCAM Down syndrome cell adhesion molecule 4.0
ZFYVE27 zinc finger, FYVE domain containing 27 4.0
ATOH7 atonal homolog 7 (Drosophila) 4.0
DBN1 drebrin 1 4.0
MYO1D myosin ID 4.0
CLDN11 claudin 11 4.0
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 4.0
DPYSL3 dihydropyrimidinase-like 3 4.0
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 4.0
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 4.0
ERC2 ELKS/RAB6-interacting/CAST family member 2 4.0
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 4.0
ADAM22 ADAM metallopeptidase domain 22 4.0
ABITRAM actin binding transcription modulator 4.0
GRIK3 glutamate receptor, ionotropic, kainate 3 4.0
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 4.0
RTN4RL2 reticulon 4 receptor-like 2 4.0
LAMP5 lysosomal-associated membrane protein family, member 5 4.0
FGF13 fibroblast growth factor 13 4.0
IGHMBP2 immunoglobulin mu binding protein 2 4.0
THY1 Thy-1 cell surface antigen 4.0
DTNBP1 dystrobrevin binding protein 1 4.0
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 4.0
GRM7 glutamate receptor, metabotropic 7 4.0
NRSN1 neurensin 1 4.0
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 4.0
NFIB nuclear factor I/B 4.0
SEPTIN14 septin 14 4.0
SEPTIN4 septin 4 4.0
ATCAY ataxia, cerebellar, Cayman type 4.0
ANG angiogenin, ribonuclease, RNase A family, 5 4.0
RNF6 ring finger protein (C3H2C3 type) 6 4.0
PRRT2 proline-rich transmembrane protein 2 4.0
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 4.0
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 4.0
ELAVL4 ELAV like neuron-specific RNA binding protein 4 4.0
AAK1 AP2 associated kinase 1 4.0
CPNE6 copine VI (neuronal) 4.0
FRMD7 FERM domain containing 7 4.0
KIRREL3 kin of IRRE like 3 (Drosophila) 4.0
IQGAP1 IQ motif containing GTPase activating protein 1 4.0
PTPRU protein tyrosine phosphatase, receptor type, U 4.0
PTPRS protein tyrosine phosphatase, receptor type, S 4.0
SSNA1 Sjogren syndrome nuclear autoantigen 1 4.0
L1CAM L1 cell adhesion molecule 4.0
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 4.0
CDK5 cyclin-dependent kinase 5 4.0
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 4.0
DVL1 dishevelled segment polarity protein 1 4.0
SACS sacsin molecular chaperone 4.0
PTPRN protein tyrosine phosphatase, receptor type, N 4.0
GPM6A glycoprotein M6A 4.0
ZPR1 ZPR1 zinc finger 4.0
TPRG1L tumor protein p63 regulated 1-like 4.0
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 4.0
FSCN1 fascin actin-bundling protein 1 4.0
TOR1A torsin family 1, member A (torsin A) 4.0
ALCAM activated leukocyte cell adhesion molecule 4.0
PKN1 protein kinase N1 4.0
DAB2IP DAB2 interacting protein 4.0
RTN4R reticulon 4 receptor 4.0
LGI3 leucine-rich repeat LGI family, member 3 4.0
TGFB2 transforming growth factor, beta 2 4.0
SHTN1 shootin 1 4.0
CD200 CD200 molecule 4.0
NCMAP noncompact myelin associated protein 4.0
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 4.0
NF1 neurofibromin 1 4.0
CPT1C carnitine palmitoyltransferase 1C 4.0
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 4.0
OLFM1 olfactomedin 1 4.0
SIRT2 sirtuin 2 4.0
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 4.0
GPER1 G protein-coupled estrogen receptor 1 4.0
SRCIN1 SRC kinase signaling inhibitor 1 4.0
FLRT3 fibronectin leucine rich transmembrane protein 3 4.0
FMR1 fragile X mental retardation 1 4.0
ADCY8 adenylate cyclase 8 (brain) 4.0
APP amyloid beta (A4) precursor protein 4.0
KCNK4 potassium channel, two pore domain subfamily K, member 4 4.0
VSTM5 V-set and transmembrane domain containing 5 4.0
KCNK2 potassium channel, two pore domain subfamily K, member 2 4.0
SLC38A7 solute carrier family 38, member 7 4.0
ATP7A ATPase, Cu++ transporting, alpha polypeptide 4.0
CTNNA2 catenin (cadherin-associated protein), alpha 2 4.0
LRP2 low density lipoprotein receptor-related protein 2 4.0
FYCO1 FYVE and coiled-coil domain containing 1 4.0
RIPK2 receptor-interacting serine-threonine kinase 2 4.0
LRRK2 leucine-rich repeat kinase 2 4.0
CXADR coxsackie virus and adenovirus receptor 4.0
SYAP1 synapse associated protein 1 4.0
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 4.0
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 4.0
ADGRL3 adhesion G protein-coupled receptor L3 4.0
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 4.0
PINK1 PTEN induced putative kinase 1 4.0
HDAC6 histone deacetylase 6 4.0
TMEM108 transmembrane protein 108 4.0
KLC1 kinesin light chain 1 4.0
RORA RAR-related orphan receptor A 4.0
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 4.0
TWF2 twinfilin actin binding protein 2 4.0
AUTS2 autism susceptibility candidate 2 4.0
ADGRL1 adhesion G protein-coupled receptor L1 4.0
DOCK7 dedicator of cytokinesis 7 4.0
EPHA5 EPH receptor A5 4.0
EPHA4 EPH receptor A4 4.0
PARD3 par-3 family cell polarity regulator 4.0
CRHBP corticotropin releasing hormone binding protein 4.0
UNC5C unc-5 homolog C (C. elegans) 4.0
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 3.0
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 3.0
NEXN nexilin (F actin binding protein) 3.0
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 3.0
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 3.0
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 3.0
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3.0
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 3.0
MTMR2 myotubularin related protein 2 3.0
DCC DCC netrin 1 receptor 3.0
MUL1 mitochondrial E3 ubiquitin protein ligase 1 3.0
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.0
NRP1 neuropilin 1 3.0
CPLX2 complexin 2 3.0
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 3.0
DSCAML1 Down syndrome cell adhesion molecule like 1 3.0
CALCR calcitonin receptor 3.0
SCN10A sodium channel, voltage gated, type X alpha subunit 3.0
PCLO piccolo presynaptic cytomatrix protein 3.0
NEO1 neogenin 1 3.0
SYNJ1 synaptojanin 1 3.0
TAOK2 TAO kinase 2 3.0
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 3.0
SCN1B sodium channel, voltage gated, type I beta subunit 3.0
ACTL9 actin-like 9 3.0
PENK proenkephalin 3.0
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 3.0
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 3.0
HMCN2 hemicentin 2 3.0
VIM vimentin 3.0
PRPH2 peripherin 2 (retinal degeneration, slow) 3.0
EMB embigin 3.0
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 3.0
PARK7 parkinson protein 7 3.0
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 3.0
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.0
NRCAM neuronal cell adhesion molecule 3.0
ACOD1 aconitate decarboxylase 1 3.0
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 3.0
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 3.0
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 3.0
EPB41L3 erythrocyte membrane protein band 4.1-like 3 3.0
BOC BOC cell adhesion associated, oncogene regulated 3.0
SHANK2 SH3 and multiple ankyrin repeat domains 2 3.0
KIF5C kinesin family member 5C 3.0
MYPN myopalladin 3.0
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 3.0
METAP2 methionyl aminopeptidase 2 3.0
TBC1D24 TBC1 domain family, member 24 3.0
MAP1B microtubule-associated protein 1B 3.0
FKBP15 FK506 binding protein 15, 133kDa 3.0
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 3.0
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 3.0
SYT8 synaptotagmin VIII 3.0
CD2AP CD2-associated protein 3.0
SYT1 synaptotagmin I 3.0
SYT2 synaptotagmin II 3.0
SYT4 synaptotagmin IV 3.0
NTS neurotensin 3.0
SYT5 synaptotagmin V 3.0
SYT7 synaptotagmin VII 3.0
METAP1 methionyl aminopeptidase 1 3.0
SYT12 synaptotagmin XII 3.0
NPFF neuropeptide FF-amide peptide precursor 3.0
INSRR insulin receptor-related receptor 3.0
NFASC neurofascin 3.0
MYOT myotilin 3.0
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 3.0
LZTS1 leucine zipper, putative tumor suppressor 1 3.0
RIN3 Ras and Rab interactor 3 3.0
NAV1 neuron navigator 1 3.0
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.0
BRSK1 BR serine/threonine kinase 1 3.0
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 3.0
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 3.0
IGF1R insulin-like growth factor 1 receptor 3.0
UNC80 unc-80 homolog (C. elegans) 3.0
CDKL5 cyclin-dependent kinase-like 5 3.0
CNTN5 contactin 5 3.0
CNTN4 contactin 4 3.0
CNTN6 contactin 6 3.0
CNTN1 contactin 1 3.0
PTK2B protein tyrosine kinase 2 beta 3.0
PALLD palladin, cytoskeletal associated protein 3.0
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.0
CPLX3 complexin 3 3.0
BRSK2 BR serine/threonine kinase 2 3.0
NRP2 neuropilin 2 3.0
CRHR2 corticotropin releasing hormone receptor 2 3.0
CNTF ciliary neurotrophic factor 3.0
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 3.0
EXOC4 exocyst complex component 4 3.0
CNTN2 contactin 2 (axonal) 3.0
GRM3 glutamate receptor, metabotropic 3 3.0
GRM2 glutamate receptor, metabotropic 2 3.0
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 3.0
BIN1 bridging integrator 1 3.0
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.0
OPHN1 oligophrenin 1 3.0
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 3.0
CDHR3 cadherin-related family member 3 3.0
CNTNAP1 contactin associated protein 1 3.0
NMU neuromedin U 3.0
DRD2 dopamine receptor D2 3.0
CPLX4 complexin 4 3.0
CPLX1 complexin 1 3.0
CDH8 cadherin 8, type 2 3.0
NRXN1 neurexin 1 3.0
SCN11A sodium channel, voltage gated, type XI alpha subunit 3.0
BDNF brain-derived neurotrophic factor 3.0
CALB2 calbindin 2 3.0
SCN8A sodium channel, voltage gated, type VIII alpha subunit 3.0
GHRH growth hormone releasing hormone 3.0
LLGL1 lethal giant larvae homolog 1 (Drosophila) 3.0
SPG11 spastic paraplegia 11 (autosomal recessive) 3.0
OMP olfactory marker protein 3.0
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 3.0
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 3.0
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 3.0
BAG2 BCL2-associated athanogene 2 3.0
GSK3B glycogen synthase kinase 3 beta 3.0
GSK3A glycogen synthase kinase 3 alpha 3.0
POTEE POTE ankyrin domain family, member E 3.0
POTEF POTE ankyrin domain family, member F 3.0
POTEI POTE ankyrin domain family, member I 3.0
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 3.0
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.0
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 3.0
NEFH neurofilament, heavy polypeptide 3.0
NEFM neurofilament, medium polypeptide 3.0
KIF1C kinesin family member 1C 3.0
KIF1B kinesin family member 1B 3.0
KIF1A kinesin family member 1A 3.0
INSR insulin receptor 3.0
SPTBN4 spectrin, beta, non-erythrocytic 4 3.0
MMP12 matrix metallopeptidase 12 3.0
SPTBN1 spectrin, beta, non-erythrocytic 1 3.0
NGF nerve growth factor (beta polypeptide) 3.0
POTEJ POTE ankyrin domain family, member J 3.0
RAB5A RAB5A, member RAS oncogene family 3.0
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.0
CNTNAP2 contactin associated protein-like 2 3.0
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 3.0
UNC13C unc-13 homolog C (C. elegans) 3.0
UNC13B unc-13 homolog B (C. elegans) 3.0
IGSF9 immunoglobulin superfamily, member 9 3.0
SCN9A sodium channel, voltage gated, type IX alpha subunit 3.0
CIB1 calcium and integrin binding 1 (calmyrin) 3.0
UNC13A unc-13 homolog A (C. elegans) 3.0
AP3D1 adaptor-related protein complex 3, delta 1 subunit 3.0
RAB3A RAB3A, member RAS oncogene family 3.0
DCTN1 dynactin 1 3.0
PDYN prodynorphin 3.0
TH tyrosine hydroxylase 3.0
UHMK1 U2AF homology motif (UHM) kinase 1 3.0
MAP9 microtubule-associated protein 9 3.0
SCGN secretagogin, EF-hand calcium binding protein 3.0
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 3.0
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 3.0
ACTG1 actin gamma 1 3.0
SCN2A sodium channel, voltage gated, type II alpha subunit 3.0
LRRC7 leucine rich repeat containing 7 3.0
COBL cordon-bleu WH2 repeat protein 3.0
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 3.0
TUBB3 tubulin, beta 3 class III 3.0
LDLRAP1 low density lipoprotein receptor adaptor protein 1 3.0
SNAP25 synaptosomal-associated protein, 25kDa 3.0
SNCB synuclein, beta 3.0
TRIM46 tripartite motif containing 46 3.0
CALB1 calbindin 1, 28kDa 3.0
STX3 syntaxin 3 3.0
PNOC prepronociceptin 3.0
COMT catechol-O-methyltransferase 3.0
GPRIN1 G protein regulated inducer of neurite outgrowth 1 3.0
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 3.0
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 3.0
PTK7 protein tyrosine kinase 7 (inactive) 3.0
SNCG synuclein, gamma (breast cancer-specific protein 1) 3.0
NTF4 neurotrophin 4 3.0
FSCN3 fascin actin-bundling protein 3, testicular 3.0
MAP6 microtubule-associated protein 6 3.0
MAP7 microtubule-associated protein 7 3.0
MAP4 microtubule-associated protein 4 3.0
ACTBL2 actin, beta-like 2 3.0
RET ret proto-oncogene 3.0
TRPV4 transient receptor potential cation channel, subfamily V, member 4 3.0
MAPT microtubule-associated protein tau 3.0
BSN bassoon presynaptic cytomatrix protein 3.0
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 3.0
NTF3 neurotrophin 3 3.0
MAPK8 mitogen-activated protein kinase 8 3.0